Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice

Pathogenesis of nonalcoholic steatohepatitis

(2016) Wensheng Liu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Metabolic flexibility and oxidative capacity independently associate with insulin sensitivity in individuals with newly diagnosed type 2 diabetes

(2016) Maria Apostolopoulou et al.   DIABETOLOGIA

Developmental origins of NAFLD: a womb with a clue

(2016) Stephanie R. Wesolowski et al.   Nature Reviews Gastroenterology & Hepatology

Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?

(2016) Kelli A. Lytle et al.   PLoS One

Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations

(2016) Jessica L. Saben et al.   Cell Reports

Identification of lactate dehydrogenase as a mammalian pyrroloquinoline quinone (PQQ)-binding protein

(2016) Mitsugu Akagawa et al.   Scientific Reports

Pyrroloquinoline quinone (PQQ) has potential to ameliorate streptozotocin-induced diabetes mellitus and oxidative stress in mice: A histopathological and biochemical study

(2015) Narendra Kumar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Pyrroloquinoline Quinone Decelerates Rheumatoid Arthritis Progression by Inhibiting Inflammatory Responses and Joint Destruction via Modulating NF-κB and MAPK Pathways

(2015) Zhongbing Liu et al.   INFLAMMATION

Pyrroloquinoline Quinone Slows Down the Progression of Osteoarthritis by Inhibiting Nitric Oxide Production and Metalloproteinase Synthesis

(2015) Ran Tao et al.   INFLAMMATION

Effects of Pyrroloquinoline Quinone Disodium Salt Intake on the Serum Cholesterol Levels of Healthy Japanese Adults

(2015) Masahiko NAKANO et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Effects of Orally Administered Pyrroloquinoline Quinone Disodium Salt on Dry Skin Conditions in Mice and Healthy Female Subjects

(2015) Masahiko NAKANO et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Peri-conception parental obesity, reproductive health, and transgenerational impacts

(2015) Michelle Lane et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Pyrroloquinoline-Quinone Suppresses Liver Fibrogenesis in Mice

(2015) Dongwei Jia et al.   PLoS One

Effects of dietary pyrroloquinoline quinone disodium on growth performance, carcass yield and antioxidant status of broiler chicks

(2014) K. G. Samuel et al.   Animal

Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates

(2014) Victoria H. J. Roberts et al.   FASEB JOURNAL

Triolein and Trilinolein Ameliorate Oxidized Low-Density Lipoprotein-Induced Oxidative Stress in Endothelial Cells

(2014) Ting Luo et al.   LIPIDS

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014) Gerald I. Shulman   NEW ENGLAND JOURNAL OF MEDICINE

Heparin modulation on hepatic nitric oxide synthase in experimental steatohepatitis

(2014) AMAL HASSANIN et al.   Experimental and Therapeutic Medicine

Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring

(2013) M. G. M. Pruis et al.   Acta Physiologica

Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice

(2013) Angelina Mouralidarane et al.   HEPATOLOGY

Extrahepatic complications of nonalcoholic fatty liver disease

(2013) Matthew J. Armstrong et al.   HEPATOLOGY

Ceramides and Glucosylceramides Are Independent Antagonists of Insulin Signaling

(2013) Jose A. Chavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects

(2013) Calliandra B. Harris et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

LipidBlast in silico tandem mass spectrometry database for lipid identification

(2013) Tobias Kind et al.   NATURE METHODS

Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus

(2013) Tineke van de Weijer et al.   PLoS One

Transgenic Increase in N-3/N-6 Fatty Acid Ratio Reduces Maternal Obesity-Associated Inflammation and Limits Adverse Developmental Programming in Mice

(2013) Margaret J. R. Heerwagen et al.   PLoS One

Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™)

(2013) Masahiko Nakano et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A role for sphingolipids in the pathophysiology of obesity-induced inflammation

(2012) Benjamin T. Bikman   CELLULAR AND MOLECULAR LIFE SCIENCES

Intrahepatic Fat Is Increased in the Neonatal Offspring of Obese Women with Gestational Diabetes

(2012) David E. Brumbaugh et al.   JOURNAL OF PEDIATRICS

Role of ceramides in nonalcoholic fatty liver disease

(2012) Mangesh Pagadala et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Exercise reduces appetite and traffics excess nutrients away from energetically efficient pathways of lipid deposition during the early stages of weight regain

(2011) Amy J. Steig et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ)

(2011) Erdenezaya Odkhuu et al.   IMMUNOLOGY LETTERS

Altering Pyrroloquinoline Quinone Nutritional Status Modulates Mitochondrial, Lipid, and Energy Metabolism in Rats

(2011) Kathryn Bauerly et al.   PLoS One

Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats

(2010) Erin D. Giles et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways

(2010) Eskouhie Tchaparian et al.   BIOCHEMICAL JOURNAL

Maternal Antioxidant Supplementation Prevents Adiposity in the Offspring of Western Diet-Fed Rats

(2010) S. Sen et al.   DIABETES

High-Fat Diet Causes Lipotoxicity Responses in Cumulus–Oocyte Complexes and Decreased Fertilization Rates

(2010) Linda Lin-Yan Wu et al.   ENDOCRINOLOGY

Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice

(2010) Jude A. Oben et al.   JOURNAL OF HEPATOLOGY

Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice

(2010) Ryan S. Lim et al.   JOURNAL OF LIPID RESEARCH

Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes

(2010) Natalia Igosheva et al.   PLoS One

Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression

(2009) Kimberley D. Bruce et al.   HEPATOLOGY

Pyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression

(2009) Winyoo Chowanadisai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPAR control: it's SIRTainly as easy as PGC

(2009) Mary C Sugden et al.   JOURNAL OF ENDOCRINOLOGY

Weight regain after sustained weight reduction is accompanied by suppressed oxidation of dietary fat and adipocyte hyperplasia

(2008) Matthew R. Jackman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

(2008) Vitali Matyash et al.   JOURNAL OF LIPID RESEARCH

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION