Vibration-Induced-Emission (VIE) for imaging amyloid β fibrils

Targeted Intracellular Production of Reactive Oxygen Species by a 2D Molybdenum Disulfide Glycosheet

(2016) Ding-Kun Ji et al.   ADVANCED MATERIALS

Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues

(2016) Yun-Han Ma et al.   ADVANCED MATERIALS

Rapid Identification of the Receptor-Binding Specificity of Influenza A Viruses by Fluorogenic Glycofoldamers

(2016) Xiao-Peng He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu-catalyzed C–H amination/Ullmann N-arylation domino reaction: a straightforward synthesis of 9,14-diaryl-9,14-dihydrodibenzo[a,c]phenazine

(2016) Huan Wang et al.   CHEMICAL COMMUNICATIONS

Amyloid β-Protein Assembly and Alzheimer’s Disease: Dodecamers of Aβ42, but Not of Aβ40, Seed Fibril Formation

(2016) Nicholas J. Economou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phenazine-Based Ratiometric Hg2+Probes with Well-Resolved Dual Emissions: A New Sensing Mechanism by Vibration-Induced Emission (VIE)

(2016) Haitao Zhou et al.   Small

Foldable glycoprobes capable of fluorogenic crosslinking of biomacromolecules

(2016) Kai-Bin Li et al.   Chemical Science

In Vivo Detection of Cerebral Amyloid Fibrils with Smart Dicynomethylene-4H-Pyran-Based Fluorescence Probe

(2015) Yan Cheng et al.   ANALYTICAL CHEMISTRY

Colour-tunable fluorescence of single molecules based on the vibration induced emission of phenazine

(2015) Wei Huang et al.   CHEMICAL COMMUNICATIONS

In vivo fluorescence imaging of β-amyloid plaques with push–pull dimethylaminothiophene derivatives

(2015) Hiroyuki Watanabe et al.   CHEMICAL COMMUNICATIONS

Diarylethene based fluorescent switchable probes for the detection of amyloid-β pathology in Alzheimer's disease

(2015) Guanglei Lv et al.   CHEMICAL COMMUNICATIONS

Probing disease-related proteins with fluorogenic composite materials

(2015) Xiao-Peng He et al.   CHEMICAL SOCIETY REVIEWS

Structure–Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents That Selectively Detect Neurofibrillary Tangles in Alzheimer’s Disease Brains

(2015) Kenji Matsumura et al.   JOURNAL OF MEDICINAL CHEMISTRY

Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-β Plaques in Alzheimer’s Disease

(2015) Hualong Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Excited-State Conformational/Electronic Responses of Saddle-Shaped N,N′-Disubstituted-Dihydrodibenzo[a,c]phenazines: Wide-Tuning Emission from Red to Deep Blue and White Light Combination

(2015) Zhiyun Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background Signal

(2015) Dokyoung Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Fluorescent Probe for Detection of Aβ Oligomers

(2015) Chai Lean Teoh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting protein aggregation for the treatment of degenerative diseases

(2015) Yvonne S. Eisele et al.   NATURE REVIEWS DRUG DISCOVERY

Photoluminescence Architectures for Disease Diagnosis: From Graphene to Thin-Layer Transition Metal Dichalcogenides and Oxides

(2015) Xiao-Peng He et al.   Small

Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer׳s disease

(2015) Hongjuan Tong et al.   Acta Pharmaceutica Sinica B

Detection of Aβ plaques in mouse brain by using a disaggregation-induced fluorescence-enhancing probe

(2014) Yeon Ok Lee et al.   CHEMICAL COMMUNICATIONS

Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models

(2013) Bing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Bivalent Ligand Containing Curcumin and Cholesterol as a Fluorescence Probe for Aβ Plaques in Alzheimer’s Disease

(2011) Kai Liu et al.   ACS Chemical Neuroscience

Intra-membrane Oligomerization and Extra-membrane Oligomerization of Amyloid-β Peptide Are Competing Processes as a Result of Distinct Patterns of Motif Interplay

(2011) Yi-Jiong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology