Canakinumab for the treatment of familial Mediterranean fever

Association of hidradenitis suppurativa and familial Mediterranean fever: A case series of 6 patients

(2017) Salam Abbara et al.   JOINT BONE SPINE

Anakinra for Colchicine-Resistant Familial Mediterranean Fever: A Randomized, Double-Blind, Placebo-Controlled Trial

(2017) Ilan Ben-Zvi et al.   Arthritis & Rheumatology

Development and initial validation of international severity scoring system for familial Mediterranean fever (ISSF)

(2016) Erkan Demirkaya et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR recommendations for the management of familial Mediterranean fever: Table 1

(2016) Seza Ozen et al.   ANNALS OF THE RHEUMATIC DISEASES

Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study

(2016) Marco Gattorno et al.   ANNALS OF THE RHEUMATIC DISEASES

Preclinical characterization and clinical development of ILARIS® (canakinumab) for the treatment of autoinflammatory diseases

(2016) Hermann Gram   CURRENT OPINION IN CHEMICAL BIOLOGY

Canakinumab investigated for treating familial Mediterranean fever

(2016) Ruby Haviv et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis

(2016) Haiying Sun et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Anti-interleukin-1 treatment in 26 patients with refractory familial mediterranean fever

(2016) Orhan Kucuksahin et al.   Modern Rheumatology

Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS

(2016) Yong Hwan Park et al.   NATURE IMMUNOLOGY

Spondyloarthritis associated with familial Mediterranean fever: successful treatment with anakinra

(2016) Sophie Georgin-Lavialle et al.   RHEUMATOLOGY

Colchicine: Old and New

(2015) Anastasia Slobodnick et al.   AMERICAN JOURNAL OF MEDICINE

Tocilizumab is effective in a familial Mediterranean fever patient complicated with histologically proven recurrent fasciitis and myositis

(2015) Masataka Umeda et al.   International Journal of Rheumatic Diseases

Tolerance and efficacy of off-label anti-interleukin-1 treatments in France: a nationwide survey

(2015) Linda Rossi-Semerano et al.   Orphanet Journal of Rare Diseases

Early detection of sensorineural hearing loss in Muckle-Wells-syndrome

(2015) Jasmin B. Kuemmerle-Deschner et al.   Pediatric Rheumatology

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature

(2015) Direkrit Chiewchengchol et al.   Pediatric Rheumatology

Treatment of colchicine-resistant Familial Mediterranean fever in children and adolescents

(2015) Fehime Kara Eroglu et al.   RHEUMATOLOGY INTERNATIONAL

Efficacy and safety of canakinumab in adolescents and adults with colchicine-resistant familial Mediterranean fever

(2015) Ahmet Gül et al.   ARTHRITIS RESEARCH & THERAPY

FMF50: a score for assessing outcome in familial Mediterranean fever

(2014) Seza Ozen et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-IL-1 treatment in familial Mediterranean fever and related amyloidosis

(2014) Z. Birsin Özçakar et al.   CLINICAL RHEUMATOLOGY

Efficacy of Interleukin-1 Targeting Treatments in Patients with Familial Mediterranean Fever

(2014) Pinar Cetin et al.   INFLAMMATION

Interleukin-1 targeting treatment in familial Mediterranean fever: an experience of pediatric patients

(2014) Özge Başaran et al.   Modern Rheumatology

Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

(2014) Hao Xu et al.   NATURE

The immunological function of familial Mediterranean fever disease protein Pyrin

(2014) JieLing Yang et al.   Science China-Life Sciences

Canakinumab for the Treatment of Children With Colchicine-Resistant Familial Mediterranean Fever: A 6-Month Open-Label, Single-Arm Pilot Study

(2014) Riva Brik et al.   Arthritis & Rheumatology

A76: Long-Term Efficacy of Canakinumab in Childhood Colchicine Resistant Familial Mediterranean Fever

(2014) Philip Hashkes et al.   Arthritis & Rheumatology

Rilonacept for Colchicine-Resistant or -Intolerant Familial Mediterranean Fever

(2013) Philip J. Hashkes et al.   ANNALS OF INTERNAL MEDICINE

Long-Term Safety and Efficacy of Rilonacept in Patients With Systemic Juvenile Idiopathic Arthritis

(2013) Daniel J. Lovell et al.   ARTHRITIS AND RHEUMATISM

Anakinra for cryopyrin-associated periodic syndrome

(2013) Isabelle Koné-Paut et al.   Expert Review of Clinical Immunology

Pharmacokinetic and pharmacodynamic properties of canakinumab in patients with gouty arthritis

(2013) Abhijit Chakraborty et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Rilonacept for gout flare prevention during initiation of uric acid-lowering therapy: results from the PRESURGE-2 international, phase 3, randomized, placebo-controlled trial

(2013) Essack Mitha et al.   RHEUMATOLOGY

Evidence-based recommendations for the practical management of Familial Mediterranean Fever

(2013) Véronique Hentgen et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions

(2012) Naomi Schlesinger et al.   ANNALS OF THE RHEUMATIC DISEASES

Pharmacokinetic and Pharmacodynamic Properties of Canakinumab, a Human Anti-Interleukin-1β Monoclonal Antibody

(2012) Abhijit Chakraborty et al.   CLINICAL PHARMACOKINETICS

Colchicine is a Safe Drug in Children with Familial Mediterranean Fever

(2012) Shai Padeh et al.   JOURNAL OF PEDIATRICS

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis

(2012) Nicolino Ruperto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Canakinumab induces remission in a patient with resistant familial Mediterranean fever

(2012) D. O. Hacihamdioglu et al.   RHEUMATOLOGY

The efficacy of canakinumab in the treatment of a patient with familial Mediterranean fever and longstanding destructive arthritis

(2011) I. Mitroulis et al.   ANNALS OF THE RHEUMATIC DISEASES

Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes

(2011) J. B. Kuemmerle-Deschner et al.   ANNALS OF THE RHEUMATIC DISEASES

A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features

(2011) Nicolino Ruperto et al.   ARTHRITIS AND RHEUMATISM

The regulation of MEFV expression and its role in health and familial Mediterranean fever

(2011) S Grandemange et al.   GENES AND IMMUNITY

Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

(2011) Jae Jin Chae et al.   IMMUNITY

Interleukin-1 Targeting Drugs in Familial Mediterranean Fever: A Case Series and a Review of the Literature

(2011) Ulrich Meinzer et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France

(2010) L. Cuisset et al.   ANNALS OF THE RHEUMATIC DISEASES

Decrease in the rate of secondary amyloidosis in Turkish children with FMF: are we doing better?

(2010) Victoria Akse-Önal et al.   EUROPEAN JOURNAL OF PEDIATRICS

Familial Mediterranean Fever in the World

(2009) Eldad Ben-Chetrit et al.   ARTHRITIS AND RHEUMATISM

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

(2009) Helen J. Lachmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

(2009) Helen J. Lachmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Population Genetics of Familial Mediterranean Fever: A Meta-Analysis Study

(2008) V. P. Papadopoulos et al.   ANNALS OF HUMAN GENETICS

Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies

(2008) Hal M. Hoffman et al.   ARTHRITIS AND RHEUMATISM

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY