Aminoglycosides against carbapenem-resistant Enterobacteriaceae in the critically ill: the pitfalls of aminoglycoside susceptibility

Aminoglycosides for Treatment of Bacteremia Due to Carbapenem-Resistant Klebsiella pneumoniae

(2016) Ryan K. Shields et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Association between the Presence of Aminoglycoside-Modifying Enzymes andIn VitroActivity of Gentamicin, Tobramycin, Amikacin, and Plazomicin against Klebsiella pneumoniae Carbapenemase- and Extended-Spectrum-β-Lactamase-Producing Enterobacter Species

(2016) Ghady Haidar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The antibiotic pipeline for multi-drug resistant gram negative bacteria: what can we expect?

(2016) Matthew E. Falagas et al.   Expert Review of Anti-Infective Therapy

Resistance suppression by high-intensity, short-duration aminoglycoside exposure against hypermutable and non-hypermutablePseudomonas aeruginosa

(2016) Vanessa E. Rees et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A high-dose aminoglycoside regimen combined with renal replacement therapy for the treatment of MDR pathogens: a proof-of-concept study

(2016) Alexandre Brasseur et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Urinary Tract Infections and Surgical Site Infections due to Carbapenem-Resistant Enterobacteriaceae in Renal Transplant

(2016) B.G. Rodrigues dos Santos et al.   TRANSPLANTATION PROCEEDINGS

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(2016)   INTERNAL MEDICINE JOURNAL

Novel Approach To Optimize Synergistic Carbapenem-Aminoglycoside Combinations against Carbapenem-Resistant Acinetobacter baumannii

(2015) Rajbharan Yadav et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Optimizing the Initial Amikacin Dosage in Adults

(2015) Bryan P. White et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Two Mechanisms of Killing of Pseudomonas aeruginosa by Tobramycin Assessed at Multiple Inocula via Mechanism-Based Modeling

(2015) Jürgen B. Bulitta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First-dose pharmacokinetics of aminoglycosides in critically ill haematological malignancy patients

(2015) Laura M. Blackburn et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In vitro activity of the next-generation aminoglycoside plazomicin alone and in combination with colistin, meropenem, fosfomycin or tigecycline against carbapenemase-producing Enterobacteriaceae strains

(2015) Iciar Rodríguez-Avial et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations

(2015) Claire Roger et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis

(2015) Claire Roger et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

KPC-Producing Klebsiella pneumoniae Strains That Harbor AAC(6′)-Ib Exhibit Intermediate Resistance to Amikacin

(2014) Derek N. Bremmer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenem-Resistant Klebsiella pneumoniae Strains Exhibit Diversity in Aminoglycoside-Modifying Enzymes, Which Exert Differing Effects on Plazomicin and Other Agents

(2014) Reem Almaghrabi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia

(2014) C. Burdet et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Colistin resistance superimposed to endemic carbapenem-resistant Klebsiella pneumoniae: a rapidly evolving problem in Italy, November 2013 to April 2014

(2014) M. Monaco et al.   Eurosurveillance

Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen

(2014) Etienne de Montmollin et al.   INTENSIVE CARE MEDICINE

Combination therapy for carbapenem-resistant Gram-negative bacteria

(2014) M. Paul et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Gentamicin therapy for sepsis due to carbapenem-resistant and colistin-resistant Klebsiella pneumoniae

(2014) M. Gonzalez-Padilla et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Infections caused by carbapenem-resistant Klebsiella pneumoniae among patients in intensive care units in Greece: a multi-centre study on clinical outcome and therapeutic options

(2013) F. Kontopidou et al.   CLINICAL MICROBIOLOGY AND INFECTION

Combination therapy for carbapenem-resistant Gram-negative bacteria

(2013) Alexandre P Zavascki et al.   Expert Review of Anti-Infective Therapy

Genomic analysis of the emergence and evolution of multidrug resistance during a Klebsiella pneumoniae outbreak including carbapenem and colistin resistance

(2013) E. Lopez-Camacho et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

(2013) L Silvia Munoz-Price et al.   LANCET INFECTIOUS DISEASES

Treatment and Clinical Outcomes of Urinary Tract Infections Caused by KPC-Producing Enterobacteriaceae in a Retrospective Cohort

(2012) Bryan T. Alexander et al.   CLINICAL THERAPEUTICS

Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin

(2012) George G Zhanel et al.   Expert Review of Anti-Infective Therapy

Assessment of Antimicrobial Combinations for Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae

(2012) Elizabeth B. Hirsch et al.   JOURNAL OF INFECTIOUS DISEASES

Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

(2011) G. L. Drusano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Effectiveness of Aminoglycosides, Polymyxin B, and Tigecycline for Clearance of Carbapenem-Resistant Klebsiella pneumoniae from Urine

(2011) Michael J. Satlin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Higher than recommended amikacin loading doses achieve pharmacokinetic targets without associated toxicity

(2011) Ricardo Gálvez et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In Vitro Activity of NXL104 in Combination with  -Lactams against Klebsiella pneumoniae Isolates Producing KPC Carbapenemases

(2009) A. Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA

(2009) Andrea Endimiani et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Suboptimal Aminoglycoside Dosing in Critically Ill Patients

(2008) Rhonda S Rea et al.   THERAPEUTIC DRUG MONITORING

Aminoglycoside induced ototoxicity

(2008) O’neil W. Guthrie   TOXICOLOGY