Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis

First-dose pharmacokinetics of aminoglycosides in critically ill haematological malignancy patients

(2015) Laura M. Blackburn et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations

(2015) Claire Roger et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen

(2014) Etienne de Montmollin et al.   INTENSIVE CARE MEDICINE

Surviving Sepsis Campaign

(2013) R. Phillip Dellinger et al.   CRITICAL CARE MEDICINE

Effect of Empirical Treatment With Moxifloxacin and Meropenem vs Meropenem on Sepsis-Related Organ Dysfunction in Patients With Severe Sepsis

(2012) Frank M. Brunkhorst   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Optimization of Aminoglycoside Therapy

(2011) G. L. Drusano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Higher than recommended amikacin loading doses achieve pharmacokinetic targets without associated toxicity

(2011) Ricardo Gálvez et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Reduction of the severe sepsis or septic shock associated mortality by reinforcement of the recommendations bundle: A multicenter study

(2010) J.-Y. Lefrant et al.   ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION

A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: A meta-analytic/meta-regression study

(2010) Anand Kumar et al.   CRITICAL CARE MEDICINE

Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis*

(2010) Anand Kumar et al.   CRITICAL CARE MEDICINE

Pharmacokinetic issues for antibiotics in the critically ill patient

(2009) Jason A. Roberts et al.   CRITICAL CARE MEDICINE