Clinical risks of St John’s Wort (Hypericum perforatum) co-administration

Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone

(2015) Tore Bjerregaard Stage et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Clinical Pharmacokinetics and Pharmacodynamics of the Endothelin Receptor Antagonist Macitentan

(2015) P. N. Sidharta et al.   CLINICAL PHARMACOKINETICS

Concomitant administration of rifampicin and oxcarbazepine results in a significant decrease of the active MHD metabolite of oxcarbazepine

(2015) Ali Sigaroudi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Phytochemical constituents as future antidepressants: a comprehensive review

(2015) Roodabeh Bahramsoltani et al.   REVIEWS IN THE NEUROSCIENCES

Plant-derived natural medicines for the management of depression: an overview of mechanisms of action

(2015) Marzieh Sarbandi Farahani et al.   REVIEWS IN THE NEUROSCIENCES

The Influence of Herbal Medicine on Platelet Function and Coagulation: A Narrative Review

(2015) Bradley McEwen   SEMINARS IN THROMBOSIS AND HEMOSTASIS

The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of knownCYP2C19Genotype

(2014) Christoph Markert et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Influence of St. John’s wort on the steadystate pharmacokinetics and metabolism of bosentan

(2014) Christoph Markert et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers

(2014) A. Jackson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Bioactivation of Sitaxentan in Liver Microsomes, Hepatocytes, and Expressed Human P450s with Characterization of the Glutathione Conjugate by Liquid Chromatography Tandem Mass Spectrometry

(2013) John C. L. Erve et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Effect of St John’s Wort on the Pharmacokinetics of Docetaxel

(2013) Andrew K. L. Goey et al.   CLINICAL PHARMACOKINETICS

Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships

(2013) Jiawang Liu et al.   MOLECULES

Pharmacogenetics of olanzapine metabolism

(2013) Mao Mao Söderberg et al.   PHARMACOGENOMICS

St. John’s Wort in Patients Non-responders to Clopidogrel Undergoing Percutaneous Coronary Intervention: a Single-Center Randomized Open-Label Trial (St. John’s Trial)

(2013) Catalina Trana et al.   Journal of Cardiovascular Translational Research

Pharmacokinetics and Pharmacodynamics of the Proton Pump Inhibitors

(2013) Jai Moo Shin et al.   Journal of Neurogastroenterology and Motility

Telaprevir: pharmacokinetics and drug interactions

(2012) Varun Garg et al.   ANTIVIRAL THERAPY

Overview of P-glycoprotein inhibitors: a rational outlook

(2012) Kale Mohana Raghava Srivalli et al.   Brazilian Journal of Pharmaceutical Sciences

An update on the ability of St. John's wort to affect the metabolism of other drugs

(2012) Roja Rahimi et al.   Expert Opinion on Drug Metabolism & Toxicology

Opioid Metabolism

(2012) Howard S. Smith   MAYO CLINIC PROCEEDINGS

Evaluation of the in vitro Inhibitory Impact of Hypericin on Placental Glutathione S-Transferase pi

(2012) Ozlem Dalmizrak et al.   PROTEIN JOURNAL

Interaction of St John’s wort (Hypericum perforatum) with clozapine

(2011) Annelies C.P. Van Strater et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

(2010) E. T. Ogburn et al.   DRUG METABOLISM AND DISPOSITION

St John's wort greatly reduces the concentrations of oral oxycodone

(2010) Tuija H. Nieminen et al.   EUROPEAN JOURNAL OF PAIN

Pharmacological studies in an herbal drug combination of St. John's Wort (Hypericum perforatum) and passion flower (Passiflora incarnata): In vitro and in vivo evidence of synergy between Hypericum and Passiflora in antidepressant pharmacological models

(2010) Bernd L. Fiebich et al.   FITOTERAPIA

The Effect of St Johnʼs Wort on the Pharmacodynamic Response of Clopidogrel in Hyporesponsive Volunteers and Patients: Increased Platelet Inhibition by Enhancement of CYP3A4 Metabolic Activity

(2010) Wei C Lau et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Drug interaction between St John’s wort and zolpidem in healthy subjects

(2010) Y. Hojo et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

A review of the antibacterial activity of Hypericum perforatum L.

(2010) Zeb Saddiqe et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of bupropion on simulated demand for cigarettes and the subjective effects of smoking

(2010) G. J. Madden et al.   NICOTINE & TOBACCO RESEARCH

Effect of St. John’s wort supplementation on the pharmacokinetics of bupropion in healthy male Chinese volunteers

(2010) H.-P. Lei et al.   XENOBIOTICA

Herb–Drug Interactions with St John’s Wort (Hypericum perforatum): an Update on Clinical Observations

(2009) Francesca Borrelli et al.   AAPS Journal

Reduced Efficacy of Rosuvastatin by St. John's Wort

(2009) Ram Y. Gordon et al.   AMERICAN JOURNAL OF MEDICINE

Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents

(2009) Roger J. M. Brüggemann et al.   CLINICAL INFECTIOUS DISEASES

Comparison of Human Cytochrome P450 Inhibition by the Thienopyridines Prasugrel, Clopidogrel, and Ticlopidine

(2009) Katsunobu Hagihara et al.   Drug Metabolism and Pharmacokinetics

Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

(2009) Nagy A. Farid et al.   JOURNAL OF CLINICAL PHARMACOLOGY

The inhibitory effect ofHypericum perforatumextract on morphine withdrawal syndrome in rat and comparison with clonidine

(2009) Amir Feily et al.   PHYTOTHERAPY RESEARCH

Protective effects of a flavonoid-rich extract of Hypericum perforatum L. against hydrogen peroxide-induced apoptosis in PC12 cells

(2009) Yan-Ping Zou et al.   PHYTOTHERAPY RESEARCH

Stereoselective Oxidation and Glucuronidation of Carvedilol in Human Liver and Intestinal Microsomes

(2008) Kazuya Ishida et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Molecular Mechanisms Underlying St. Johns Wort Drug Interactions

(2008) Maike Kober et al.   CURRENT DRUG METABOLISM

Metabolism of Atypical Antipsychotics: Involvement of Cytochrome P450 Enzymes and Relevance for Drug-Drug Interactions

(2008) Liana Urichuk et al.   CURRENT DRUG METABOLISM

The Effect of Hypericum perforatum (St. John’s Wort) on Experimental Colitis in Rat

(2008) Turhan Dost et al.   DIGESTIVE DISEASES AND SCIENCES

Metabolism of Quetiapine by CYP3A4 and CYP3A5 in Presence or Absence of Cytochrome B5

(2008) G. V. Bakken et al.   DRUG METABOLISM AND DISPOSITION

Metabolic Activation of Benzodiazepines by CYP3A4

(2008) K. Mizuno et al.   DRUG METABOLISM AND DISPOSITION

St John’s wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive

(2008) Liane Will-Shahab et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

(2008) Anna Lundahl et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome

(2008) David P Macfarlane et al.   JOURNAL OF ENDOCRINOLOGY

Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells

(2008) Lester M. Davids et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Gauging the clinical significance of P‐glycoprotein‐mediated herb‐drug interactions: Comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics

(2008) Bill J. Gurley et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties

(2007) Miguel Hattesohl et al.   PHYTOMEDICINE