Using zebrafish as a model to study the role of epigenetics in hearing loss

Inhibition of H3K27me3 Histone Demethylase Activity Prevents the Proliferative Regeneration of Zebrafish Lateral Line Neuromasts

(2017) Beier Bao et al.   Frontiers in Molecular Neuroscience

Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea

(2016) Wenli Ni et al.   JOURNAL OF NEUROSCIENCE

ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates

(2016) David T White et al.   Nature Protocols

Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae

(2016) Yingzi He et al.   Oncotarget

Histone deacetylase 1 is required for the development of the zebrafish inner ear

(2016) Yingzi He et al.   Scientific Reports

Inhibition of H3K9me2 Reduces Hair Cell Regeneration after Hair Cell Loss in the Zebrafish Lateral Line by Down-Regulating the Wnt and Fgf Signaling Pathways

(2016) Dongmei Tang et al.   Frontiers in Molecular Neuroscience

15 years of zebrafish chemical screening

(2015) Andrew J Rennekamp et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish

(2015) Yingzi He et al.   MOLECULAR NEUROBIOLOGY

LSD1 is Required for Hair Cell Regeneration in Zebrafish

(2015) Yingzi He et al.   MOLECULAR NEUROBIOLOGY

The Combination of Tet1 with Oct4 Generates High-Quality Mouse-Induced Pluripotent Stem Cells

(2015) Jiayu Chen et al.   STEM CELLS

Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis

(2014) Yingzi He et al.   MOLECULAR NEUROBIOLOGY

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

(2014) Wenyan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts

(2014) Yingzi He et al.   Frontiers in Cellular Neuroscience

Histone deacetylase activity is required for embryonic posterior lateral line development

(2013) Y. He et al.   CELL PROLIFERATION

DNA Demethylation in Pluripotency and Reprogramming: The Role of Tet Proteins and Cell Division

(2013) Hakan Bagci et al.   Cell Stem Cell

Global and gene specific DNA methylation changes during zebrafish development

(2013) Xiefan Fang et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Trans-2-phenylcyclopropylamine regulates zebrafish lateral line neuromast development mediated by depression of LSD1 activity

(2013) Yingzi He et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Perspectives for identification of mutations in the zebrafish: Making use of next-generation sequencing technologies for forward genetic approaches

(2013) Katrin Henke et al.   METHODS

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death

(2013) H Yu et al.   Cell Death & Disease

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

(2012) Arie B. Brinkman et al.   GENOME RESEARCH

Epigenetics, development, and cancer: Zebrafish make their mark

(2011) Raksha Mudbhary et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis

(2011) Ozren Bogdanović et al.   GENOME RESEARCH

Population genomics of wild and laboratory zebrafish (Danio rerio)

(2011) ANDREW R. WHITELEY et al.   MOLECULAR ECOLOGY

Heritable gene targeting in zebrafish using customized TALENs

(2011) Peng Huang et al.   NATURE BIOTECHNOLOGY

Structurally Designedtrans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1,,§

(2010) Shinya Mimasu et al.   BIOCHEMISTRY

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

(2010) Shayesta Seenundun et al.   EMBO JOURNAL

Histone arginine methylation

(2010) Alessandra Di Lorenzo et al.   FEBS LETTERS

Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos

(2010) Leif C. Lindeman et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

(2010) Claudia Binda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

(2010) R Alan Harris et al.   NATURE BIOTECHNOLOGY

Tiling Histone H3 Lysine 4 and 27 Methylation in Zebrafish Using High-Density Microarrays

(2010) Leif C. Lindeman et al.   PLoS One

Conservation and divergence of methylation patterning in plants and animals

(2010) S. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation

(2010) A. Zemach et al.   SCIENCE

Histone demethylases in development and disease

(2010) Marianne Terndrup Pedersen et al.   TRENDS IN CELL BIOLOGY

Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line

(2010) Allison B. Coffin et al.   Zebrafish

Developmental roles of the histone lysine demethylases

(2009) A. Nottke et al.   DEVELOPMENT

Postembryonic development of the posterior lateral line in the zebrafish

(2009) Viviana A. Nuñez et al.   EVOLUTION & DEVELOPMENT

Notch Signaling Regulates the Extent of Hair Cell Regeneration in the Zebrafish Lateral Line

(2008) E. Y. Ma et al.   JOURNAL OF NEUROSCIENCE

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

(2008) Yannick Doyon et al.   NATURE BIOTECHNOLOGY

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

The lagena (the third otolith endorgan in vertebrates)

(2008) V. I. Khorevin   NEUROPHYSIOLOGY