Protein palmitoylation: Palmitoyltransferases and their specificity

Identification of PSD-95 Depalmitoylating Enzymes

(2016) Norihiko Yokoi et al.   JOURNAL OF NEUROSCIENCE

The zDHHC family of S-acyltransferases

(2015) Kimon Lemonidis et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc

(2015) Colin D. Gottlieb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Canonical DHHC Motif Is Not Absolutely Required for the Activity of the YeastS-acyltransferases Swf1 and Pfa4

(2015) Ayelén González Montoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13S-Acyltransferases

(2015) Kimon Lemonidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5

(2015) G. Stefano Brigidi et al.   Nature Communications

ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization

(2015) David Tse Shen Lin et al.   eLife

A Mechanism Regulating G Protein-coupled Receptor Signaling That Requires Cycles of Protein Palmitoylation and Depalmitoylation

(2014) Lixia Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity

(2014) Kimon Lemonidis et al.   MOLECULAR BIOLOGY OF THE CELL

Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex

(2014) Gregory J. Fredericks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc co-ordination by the DHHC cysteine-rich domain of the palmitoyltransferase Swf1

(2013) Ayelén González Montoro et al.   BIOCHEMICAL JOURNAL

Dynamic Palmitoylation Links Cytosol-Membrane Shuttling of Acyl-protein Thioesterase-1 and Acyl-protein Thioesterase-2 with That of Proto-oncogene H-Ras Product and Growth-associated Protein-43

(2013) Eryan Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DHHC17 Palmitoylates ClipR-59 and Modulates ClipR-59 Association with the Plasma Membrane

(2013) W. Ren et al.   MOLECULAR AND CELLULAR BIOLOGY

Memory and synaptic deficits in Hip14/DHHC17 knockout mice

(2013) A. J. Milnerwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of peptide dipoles and hydrogen bonds on reactive cysteine pKavalues in fission yeast DJ-1

(2012) Peter Madzelan et al.   FEBS Journal

Palmitoylation of MPP1 (Membrane-palmitoylated Protein 1)/p55 Is Crucial for Lateral Membrane Organization in Erythroid Cells

(2012) Agnieszka Łach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DHHC ProteinS-Acyltransferases Use Similar Ping-Pong Kinetic Mechanisms but Display Different Acyl-CoA Specificities

(2012) Benjamin C. Jennings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Acyl Protein Transferases and Thioesterases Control Surface Expression of Calcium-activated Potassium Channels

(2012) Lijun Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation by DHHC5/8 Targets GRIP1 to Dendritic Endosomes to Regulate AMPA-R Trafficking

(2012) Gareth M. Thomas et al.   NEURON

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

(2011) Marion Rusch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Human DHHC proteins: A spotlight on the hidden player of palmitoylation

(2011) Justyna Korycka et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14

(2011) Kun Huang et al.   HUMAN MOLECULAR GENETICS

Endoplasmic Reticulum Localization of DHHC Palmitoyltransferases Mediated by Lysine-based Sorting Signals

(2011) Oforiwa A. Gorleku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases

(2011) Marco Bürger et al.   JOURNAL OF LIPID RESEARCH

The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain

(2011) Jennifer Greaves et al.   MOLECULAR BIOLOGY OF THE CELL

Global profiling of dynamic protein palmitoylation

(2011) Brent R Martin et al.   NATURE METHODS

The Ankyrin Repeats and DHHC S-acyl Transferase Domain of AKR1 Act Independently to Regulate Switching from Vegetative to Mating States in Yeast

(2011) Piers A. Hemsley et al.   PLoS One

Greasing Their Way: Lipid Modifications Determine Protein Association with Membrane Rafts

(2010) Ilya Levental et al.   BIOCHEMISTRY

The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

(2010) Oliver Rocks et al.   CELL

DHHC5 Interacts with PDZ Domain 3 of Post-synaptic Density-95 (PSD-95) Protein and Plays a Role in Learning and Memory

(2010) Yi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitoylation of the SNAP25 Protein Family

(2010) Jennifer Greaves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutational Analysis ofSaccharomyces cerevisiaeErf2 Reveals a Two-step Reaction Mechanism for Protein Palmitoylation by DHHC Enzymes

(2010) David A. Mitchell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Acyl-Protein Thioesterase 2 Catalizes the Deacylation of Peripheral Membrane-Associated GAP-43

(2010) Vanesa M. Tomatis et al.   PLoS One

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

(2010) D. A. Bachovchin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel motif at the C-terminus of palmitoyltransferases is essential for Swf1 and Pfa3 functionin vivo

(2009) Ayelén González Montoro et al.   BIOCHEMICAL JOURNAL

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity

(2009) Kun Huang et al.   FASEB JOURNAL

Proteome Scale Characterization of HumanS-Acylated Proteins in Lipid Raft-enriched and Non-raft Membranes

(2009) Wei Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Dynamic protein palmitoylation in cellular signaling

(2009) Tsuyoshi Iwanaga et al.   PROGRESS IN LIPID RESEARCH

Analysis of DHHC Acyltransferases Implies Overlapping Substrate Specificity and a Two-Step Reaction Mechanism

(2009) Haitong Hou et al.   TRAFFIC

Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation

(2009) Pleasantine Mill et al.   PLoS Genetics