NK cell immunesenescence is increased by psychological but not physical stress in older adults associated with raised cortisol and reduced perforin expression

Depressive symptoms are associated with reduced neutrophil function in hip fracture patients

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Depression following hip fracture is associated with increased physical frailty in older adults: the role of the cortisol: dehydroepiandrosterone sulphate ratio

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Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity

(2012) Jon Hazeldine et al.   AGING CELL

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(2012) Kristin A. Bush et al.   CELLULAR IMMUNOLOGY

NK Cells in Healthy Aging and Age-Associated Diseases

(2012) Xavier Camous et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly

(2011) Feng Qian et al.   AGING CELL

Epigenetic mechanisms in stress and adaptation

(2011) Karen R. Mifsud et al.   BRAIN BEHAVIOR AND IMMUNITY

Age-related changes in natural killer cell receptors from childhood through old age

(2011) Aline Almeida-Oliveira et al.   HUMAN IMMUNOLOGY

Immunosenescence of Human Natural Killer Cells

(2011) Inmaculada Gayoso et al.   Journal of Innate Immunity

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset

(2010) S. Lopez-Verges et al.   BLOOD

Glucocorticoid dysregulation of natural killer cell function through epigenetic modification☆

(2010) Karen Krukowski et al.   BRAIN BEHAVIOR AND IMMUNITY

Dehydroepiandrosterone as a regulator of immune cell function

(2010) Jon Hazeldine et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

Human innate immunosenescence: causes and consequences for immunity in old age

(2009) Alexander Panda et al.   TRENDS IN IMMUNOLOGY

Blood natural killer activity is reduced in men with occupational stress and job insecurity working in a university

(2008) Paolo Boscolo et al.   INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH