Synthesis of Celecoxib, Mavacoxib, SC-560, Fluxapyroxad, and Bixafen Enabled by Continuous Flow Reaction Modules

Synthesis, nematocidal activity and SAR study of novel difluoromethylpyrazole carboxamide derivatives containing flexible alkyl chain moieties

(2017) Xing-Hai Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Discovery of Potential Fungicides as Succinate Ubiquinone Oxidoreductase Inhibitors

(2017) Li Xiong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A sensitivity analysis of a numbered-up photomicroreactor system

(2017) Koen P. L. Kuijpers et al.   Reaction Chemistry & Engineering

Taming hazardous chemistry by continuous flow technology

(2016) M. Movsisyan et al.   CHEMICAL SOCIETY REVIEWS

Harnessing Thin-Film Continuous-Flow Assembly Lines

(2016) Joshua Britton et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fluoroalkyl-Substituted Diazomethanes and Their Application in a General Synthesis of Pyrazoles and Pyrazolines

(2016) Lucas Mertens et al.   CHEMISTRY-A EUROPEAN JOURNAL

Aryl Nitriles from Alkynes Using tert-Butyl Nitrite: Metal-Free Approach to C≡C Bond Cleavage

(2016) Uttam Dutta et al.   ORGANIC LETTERS

A convenient numbering-up strategy for the scale-up of gas–liquid photoredox catalysis in flow

(2016) Yuanhai Su et al.   Reaction Chemistry & Engineering

Organic Synthesis: March of the Machines

(2015) Steven V. Ley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Machine-Assisted Organic Synthesis

(2015) Steven V. Ley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

(2015) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

(2015) Benjamin Pelcman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine

(2015) Joshua Britton et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent advances in bioactive pyrazoles

(2015) Ş.Güniz Küçükgüzel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effective Nitration of Anilides and Acrylamides bytert-Butyl Nitrite

(2015) Yi-fei Ji et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Regioselective synthesis of nitrosoimidazoheterocycles using tert-butyl nitrite

(2015) Kamarul Monir et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An efficient route to 3-trifluoromethylpyrazole via cyclization/1,5-H shift and its applications in the synthesis of bioactive compounds

(2015) Yongdong Wang et al.   TETRAHEDRON

Practical preparation of challenging amides from non-nucleophilic amines and esters under flow conditions

(2014) Johannes L. Vrijdag et al.   CHEMICAL COMMUNICATIONS

Taming Hazardous Chemistry in Flow: The Continuous Processing of Diazo and Diazonium Compounds

(2014) Benjamin J. Deadman et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diazo Compounds in Continuous-Flow Technology

(2014) Simon T. R. Müller et al.   ChemSusChem

Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles

(2013) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Nitration of Olefins with tBuONO and TEMPO: Direct Access to Nitroolefins under Metal-free Conditions

(2013) Soham Maity et al.   ORGANIC LETTERS

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of diversely fluorinated pyrazoles as novel active agrochemical ingredients

(2012) Florence Giornal et al.   JOURNAL OF FLUORINE CHEMISTRY

Regioselective Radical Arylation of Anilines with Arylhydrazines

(2012) Hannelore Jasch et al.   JOURNAL OF ORGANIC CHEMISTRY

The Microwave-to-Flow Paradigm: Translating High-Temperature Batch Microwave Chemistry to Scalable Continuous-Flow Processes

(2011) Toma N. Glasnov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tert-butyl nitrite: a metal-free radical initiator for aerobic cleavage of benzylic CC bonds in compressed carbon dioxide

(2011) Cheng-Xia Miao et al.   GREEN CHEMISTRY

Continuous flow reactors: a perspective

(2011) Charlotte Wiles et al.   GREEN CHEMISTRY

Population pharmacokinetics of mavacoxib in osteoarthritic dogs

(2010) S. R. COX et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Microchemical systems for continuous-flow synthesis

(2009) Ryan L. Hartman et al.   LAB ON A CHIP