PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans

Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders

(2016) Hans O. Kalkman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Positive modulators of the α7 nicotinic receptor against neuroinflammation and cognitive impairment in Alzheimer's disease

(2016) Valentina Echeverria et al.   PROGRESS IN NEUROBIOLOGY

Development of [ 18 F]ASEM, a specific radiotracer for quantification of the α7-nAChR with positron-emission tomography

(2015) Andrew G. Horti   BIOCHEMICAL PHARMACOLOGY

The Therapeutic Potential of α7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonists for the Treatment of the Cognitive Deficits Associated with Schizophrenia

(2015) Corinne Beinat et al.   CNS DRUGS

PET imaging evaluation of [18F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates

(2015) Ansel T. Hillmer et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

A Promising PET Tracer for Imaging of α7 Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand

(2015) Rodrigo Teodoro et al.   MOLECULES

Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation

(2014) Darlene H. Brunzell et al.   Annals of the New York Academy of Sciences

A Graphical Method to Compare the in vivo Binding Potential of PET Radioligands in the Absence of a Reference Region: Application to [11C]PBR28 and [18F]PBR111 for TSPO Imaging

(2014) Qi Guo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

18F-ASEM, a Radiolabeled Antagonist for Imaging the  7-Nicotinic Acetylcholine Receptor with PET

(2014) A. G. Horti et al.   JOURNAL OF NUCLEAR MEDICINE

Human Brain Imaging of α7 nAChR with [18F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy

(2014) Dean F. Wong et al.   MOLECULAR IMAGING AND BIOLOGY

Development of Radioligands for the Imaging of ?7 Nicotinic Acetylcholine Receptors with Positron Emission Tomography

(2013) Peter Brust et al.   CURRENT DRUG TARGETS

Derivatives of Dibenzothiophene for Positron Emission Tomography Imaging of α7-Nicotinic Acetylcholine Receptors

(2013) Yongjun Gao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of motion correction methods in human brain PET imaging-A simulation study based on human motion data

(2013) Xiao Jin et al.   MEDICAL PHYSICS

Optimization of PET–MR registrations for nonhuman primates using mutual information measures: A Multi-Transform Method (MTM)

(2012) Christine M. Sandiego et al.   NEUROIMAGE

Nicotinic acetylcholine receptors: From basic science to therapeutics

(2012) Raymond Hurst et al.   PHARMACOLOGY & THERAPEUTICS

The INIA19 Template and NeuroMaps Atlas for Primate Brain Image Parcellation and Spatial Normalization

(2012) Torsten Rohlfing et al.   Frontiers in Neuroinformatics

Assessment of α7 nicotinic acetylcholine receptor availability in juvenile pig brain with [18F]NS10743

(2011) Winnie Deuther-Conrad et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

11C-NS14492 as a Novel PET Radioligand for Imaging Cerebral  7 Nicotinic Acetylcholine Receptors: In Vivo Evaluation and Drug Occupancy Measurements

(2011) A. Ettrup et al.   JOURNAL OF NUCLEAR MEDICINE

Pre-clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

(2010) H Rollema et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structural differences determine the relative selectivity of nicotinic compounds for native α4β2*-, α6β2*-, α3β4*- and α7-nicotine acetylcholine receptors

(2010) Sharon R. Grady et al.   NEUROPHARMACOLOGY

Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature

(2010) Noah S. Philip et al.   PSYCHOPHARMACOLOGY

Rat neuronal nicotinic acetylcholine receptors containing α7 subunit: pharmacological properties of ligand binding and function

(2009) Yingxian Xiao et al.   ACTA PHARMACOLOGICA SINICA

Preclinical and the first clinical studies on [11C]CHIBA-1001 for mapping α7 nicotinic receptors by positron emission tomography

(2009) Jun Toyohara et al.   ANNALS OF NUCLEAR MEDICINE

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM