Non-linear patterns in age-related DNA methylation may reflect CD4+ T cell differentiation

Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

(2016) L. Kananen et al.   BMC GENOMICS

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

(2016) Karl Bacos et al.   Nature Communications

DNA methylation and healthy human aging

(2015) Meaghan J. Jones et al.   AGING CELL

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression

(2015) Saara Marttila et al.   BMC GENOMICS

Krüppel-like factor 14 increases insulin sensitivity through activation of PI3K/Akt signal pathway

(2015) Min Yang et al.   CELLULAR SIGNALLING

Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease

(2015) Jingzhong Ding et al.   DIABETES

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

(2015) T. Ronn et al.   HUMAN MOLECULAR GENETICS

Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex

(2015) Andrew E Jaffe et al.   NATURE NEUROSCIENCE

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

(2015) Liina Tserel et al.   Scientific Reports

An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndrome

(2015) Omar Ali et al.   Clinical Epigenetics

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study

(2014) Marguerite R. Irvin et al.   CIRCULATION

Accounting for Population Stratification in DNA Methylation Studies

(2014) Richard T. Barfield et al.   GENETIC EPIDEMIOLOGY

Regulatory T Cells and the Immune Aging Process: A Mini-Review

(2014) Ann Jagger et al.   GERONTOLOGY

Epigenetics and Evolution

(2014) I. Mendizabal et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Age-related variations in the methylome associated with gene expression in human monocytes and T cells

(2014) Lindsay M. Reynolds et al.   Nature Communications

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

(2013) Elin Grundberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Adipose tissue macrophages in the development of obesity-induced inflammation, insulin resistance and type 2 Diabetes

(2013) Jongsoon Lee   ARCHIVES OF PHARMACAL RESEARCH

Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

(2013) Wei Xie et al.   CELL

A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression

(2013) Jerry Guintivano et al.   Epigenetics

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

(2013) Kenneth Day et al.   GENOME BIOLOGY

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

CpGassoc: an R function for analysis of DNA methylation microarray data

(2012) Richard T. Barfield et al.   BIOINFORMATICS

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

Age-associated DNA methylation in pediatric populations

(2012) R. S. Alisch et al.   GENOME RESEARCH

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice

(2012) L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(2012) Jordana T. Bell et al.   PLoS Genetics

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

(2011) Kerrin S Small et al.   NATURE GENETICS

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

An Association between Immunosenescence and CD4+CD25+ Regulatory T cells: A Systematic Review

(2010) Ling WANG et al.   BIOMEDICAL AND ENVIRONMENTAL SCIENCES

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection

(2010) Michael J. Cannon et al.   REVIEWS IN MEDICAL VIROLOGY

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

(2010) Graham Pawelec et al.   Immunity & Ageing

Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia

(2009) Dario A. Gutierrez et al.   Current Diabetes Reports

Trauma exposure and stress-related disorders in inner city primary care patients

(2009) Charles F. Gillespie et al.   GENERAL HOSPITAL PSYCHIATRY

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

(2009) Brock C. Christensen et al.   PLoS Genetics

Intra-individual Change Over Time in DNA Methylation With Familial Clustering

(2008) Hans T. Bjornsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

(2008) Valentina Bollati et al.   MECHANISMS OF AGEING AND DEVELOPMENT