In vitro to in vivo extrapolation of biotransformation rates for assessing bioaccumulation of hydrophobic organic chemicals in mammals

Somatic and gastrointestinal in vivo biotransformation rates of hydrophobic chemicals in fish

(2015) Justin C. Lo et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Concentration dependence of biotransformation in fish liver S9: Optimizing substrate concentrations to estimate hepatic clearance for bioaccumulation assessment

(2015) Justin C. Lo et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Intra- and Interlaboratory Reliability of a Cryopreserved Trout Hepatocyte Assay for the Prediction of Chemical Bioaccumulation Potential

(2014) Kellie A. Fay et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Predicting the Bioconcentration of Fragrance Ingredients by Rainbow Trout Using Measured Rates of in Vitro Intrinsic Clearance

(2014) Heike Laue et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In vitro biotransformation rates in fish liver S9: Effect of dosing techniques

(2014) Yung-Shan Lee et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparison of the kinetics of various biomarkers of benzo[a]pyrene exposure following different routes of entry in rats

(2014) Marjory Moreau et al.   JOURNAL OF APPLIED TOXICOLOGY

Metabolic biotransformation half-lives in fish: QSAR modeling and consensus analysis

(2013) Ester Papa et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Hepatic Clearance of 6 Polycyclic Aromatic Hydrocarbons by Isolated Perfused Trout Livers: Prediction From In Vitro Clearance by Liver S9 Fractions

(2013) John W. Nichols et al.   TOXICOLOGICAL SCIENCES

Protein and Lipid Binding Parameters in Rainbow Trout (Oncorhynchus mykiss) Blood and Liver Fractions to Extrapolate from anin VitroMetabolic Degradation Assay toin VivoBioaccumulation Potential of Hydrophobic Organic Chemicals

(2011) Beate I. Escher et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Measuring In Vitro Biotransformation Rates of Super Hydrophobic Chemicals in Rat Liver S9 Fractions Using Thin-Film Sorbent-Phase Dosing

(2011) Yung-Shan Lee et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarin

(2009) John W. Nichols et al.   AQUATIC TOXICOLOGY

A QUANTITATIVE STRUCTURE–ACTIVITY RELATIONSHIP FOR PREDICTING METABOLIC BIOTRANSFORMATION RATES FOR ORGANIC CHEMICALS IN FISH

(2009) Jon A. Arnot et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Revisiting Bioaccumulation Criteria for POPs and PBT Assessments

(2009) Frank A.P.C. Gobas et al.   Integrated Environmental Assessment and Management

In vitro biotransformation of surfactants in fish. Part I: Linear alkylbenzene sulfonate (C12-LAS) and alcohol ethoxylate (C13EO8)

(2008) Scott D. Dyer et al.   CHEMOSPHERE

LIVER MICROSOMES AND S9 FROM RAINBOW TROUT (ONCORHYNCHUS MYKISS): COMPARISON OF BASAL-LEVEL ENZYME ACTIVITIES WITH RAT AND DETERMINATION OF XENOBIOTIC INTRINSIC CLEARANCE IN SUPPORT OF BIOACCUMULATION ASSESSMENT

(2008) Xing Han et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

THE STATE OF IN VITRO SCIENCE FOR USE IN BIOACCUMULATION ASSESSMENTS FOR FISH

(2008) Anne V. Weisbrod et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Approach for extrapolating in vitro metabolism data to refine bioconcentration factor estimates

(2007) Christina E. Cowan-Ellsberry et al.   CHEMOSPHERE