Engineering bi-functional enzyme complex of formate dehydrogenase and leucine dehydrogenase by peptide linker mediated fusion for accelerating cofactor regeneration

SynLinker: an integrated system for designing linkers and synthetic fusion proteins: Fig. 1.

(2015) Chengcheng Liu et al.   BIOINFORMATICS

Synthetic fusion protein design and applications

(2015) Kai Yu et al.   BIOTECHNOLOGY ADVANCES

Artificial Multienzyme Supramolecular Device: Highly Ordered Self-Assembly of Oligomeric Enzymes In Vitro and In Vivo

(2014) Xin Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bringing functions together with fusion enzymes—from nature’s inventions to biotechnological applications

(2014) Skander Elleuche   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Efficient preparation of enantiopure l-tert-leucine through immobilized penicillin G acylase catalyzed kinetic resolution in aqueous medium

(2014) Weiming Liu et al.   BIOCHEMICAL ENGINEERING JOURNAL

Stereoselective synthesis of l-tert-leucine by a newly cloned leucine dehydrogenase from Exiguobacterium sibiricum

(2014) Jing Li et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Enzyme clustering accelerates processing of intermediates through metabolic channeling

(2014) Michele Castellana et al.   NATURE BIOTECHNOLOGY

Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm

(2014) Jinglin Fu et al.   Nature Nanotechnology

Asymmetric synthesis of a fluoxetine precursor with an artificial fusion protein of a ketoreductase and a formate dehydrogenase

(2014) Ilka Sührer et al.   PROCESS BIOCHEMISTRY

New Constitutive Vectors: Useful Genetic Engineering Tools for Biocatalysis

(2013) Youqiang Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cellulosome-based, Clostridium-derived multi-functional enzyme complexes for advanced biotechnology tool development: Advances and applications

(2013) Jeong Eun Hyeon et al.   BIOTECHNOLOGY ADVANCES

Construction of a chimeric thermoacidophilic beta-endoglucanase

(2013) Kristina Kufner et al.   BMC BIOCHEMISTRY

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Artificial Protein Complexes for Biocatalysis

(2012) Hidehiko Hirakawa et al.   TOPICS IN CATALYSIS

Substrate channeling and enzyme complexes for biotechnological applications

(2011) Y.-H. Percival Zhang   BIOTECHNOLOGY ADVANCES

Biocatalysis: Synthesis of Key Intermediates for Development of Pharmaceuticals

(2011) Ramesh N. Patel   ACS Catalysis

Enantioselective reduction of prochiral ketones by engineered bifunctional fusion proteins

(2010) Kathrin Hölsch et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Asymmetric synthesis of l-tert-leucine and l-3-hydroxyadamantylglycine using branched chain aminotransferase

(2010) Eun young Hong et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Self-renaturing enzymes: Design of an enzyme-chaperone chimera as a new approach to enzyme stabilization

(2009) Lisa M. Bergeron et al.   BIOTECHNOLOGY AND BIOENGINEERING

Construction, expression and characterization of fusion enzyme from Arthrobacter oxydans dextranase and Klebsiella pneumoniae amylase

(2009) Young-Min Kim et al.   BIOTECHNOLOGY LETTERS

Substrate channelling in an engineered bifunctional aldolase/kinase enzyme confers catalytic advantage for C–C bond formation

(2009) Laura Iturrate et al.   CHEMICAL COMMUNICATIONS

Stabilization of multimeric enzymes: Strategies to prevent subunit dissociation

(2009) Roberto Fernandez-Lafuente   ENZYME AND MICROBIAL TECHNOLOGY

Bifunctional enhancement of a β-glucanase-xylanase fusion enzyme by optimization of peptide linkers

(2008) Ping Lu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering the spatial organization of metabolic enzymes: mimicking nature's synergy

(2008) Robert J Conrado et al.   CURRENT OPINION IN BIOTECHNOLOGY

Tryptophan synthase: the workings of a channeling nanomachine

(2008) Michael F. Dunn et al.   TRENDS IN BIOCHEMICAL SCIENCES