Hypo-methylation mediates chromosomal instability in pancreatic NET

Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase

(2016) Zijie Feng et al.   CANCER RESEARCH

Stalled replication forks within heterochromatin require ATRX for protection

(2016) M S Huh et al.   Cell Death & Disease

Reading between the Lines: “ADD”-ing Histone and DNA Methylation Marks toward a New Epigenetic “Sum”

(2015) Kyung-Min Noh et al.   ACS Chemical Biology

Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours

(2015) C. P. Pipinikas et al.   ENDOCRINE-RELATED CANCER

Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1

(2015) T. Vandamme et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

ATRX represses alternative lengthening of telomeres

(2015) Christine E. Napier et al.   Oncotarget

Loss of ATRX, associated with DNA methylation pattern of chromosome end, impacted biological behaviors of astrocytic tumors

(2015) Jinquan Cai et al.   Oncotarget

Lack of Major Genome Instability in Tumors of p53 Null Rats

(2015) Roel Hermsen et al.   PLoS One

Prognostic Relevance of Aberrant DNA Methylation in G1 and G2 Pancreatic Neuroendocrine Tumors

(2014) Michele Stefanoli et al.   NEUROENDOCRINOLOGY

Prognostic and Predictive Roles of MGMT Protein Expression and Promoter Methylation in Sporadic Pancreatic Neuroendocrine Neoplasms

(2014) Anja Maria Schmitt et al.   NEUROENDOCRINOLOGY

Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors

(2013) Ilaria Marinoni et al.   GASTROENTEROLOGY

Menin mediates epigenetic regulation via histone H3 lysine 9 methylation

(2013) Y-J Yang et al.   Cell Death & Disease

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

Compromised genomic integrity impedes muscle growth after Atrx inactivation

(2012) Michael S. Huh et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a Specific Role for Menin in the Regulation of Genes Implicated in MEN1-Like Tumors

(2012) Sunita K. Agarwal et al.   PLoS One

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

(2012) Courtney A. Lovejoy et al.   PLoS Genetics

Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1Cin pancreatic endocrine tumors

(2011) Giorgio Malpeli et al.   BMC CANCER

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

Primer extension based quantitative polymerase chain reaction reveals consistent differences in the methylation status of the MGMT promoter in diffusely infiltrating gliomas (WHO grade II–IV) of adults

(2010) Erik Vassella et al.   JOURNAL OF NEURO-ONCOLOGY

VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors

(2009) A M Schmitt et al.   ENDOCRINE-RELATED CANCER

Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation

(2008) L. A. Puto et al.   GENES & DEVELOPMENT