Menin mediates epigenetic regulation via histone H3 lysine 9 methylation

The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

(2012) Jing Huang et al.   NATURE

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

(2011) Marina Lesina et al.   CANCER CELL

SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver

(2011) Atsushi Takahashi et al.   MOLECULAR CELL

The Menin Tumor Suppressor Protein Is Phosphorylated in Response to DNA Damage

(2011) Joshua Francis et al.   PLoS One

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors

(2010) Jinmi Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Paf1 complex: Platform or player in RNA polymerase II transcription?

(2010) Judith A. Jaehning   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Menin dynamics and functional insight: Take your partners

(2010) Katalin Balogh et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression

(2009) Yong-Jin Yang et al.   NUCLEIC ACIDS RESEARCH

Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin

(2009) S-B Gao et al.   ONCOGENE

The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene

(2008) L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

(2007) Manuel C. Lemos et al.   HUMAN MUTATION