Behavioral and transcriptomic profiling of mice null forLphn3, a gene implicated in ADHD and addiction

Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD)

(2014) Ike dela Peña et al.   Behavioral and Brain Functions

Association of Genes Involved in Calcium and Potassium Pathways with Opioid Dependence

(2014) Jen-Chyong Wang et al.   BIOLOGICAL PSYCHIATRY

LPHN3, a presynaptic adhesion-GPCR implicated in ADHD, regulates the strength of neocortical layer 2/3 synaptic input to layer 5

(2014) Matthew L O’Sullivan et al.   Neural Development

Lipocalin-2 is involved in emotional behaviors and cognitive function

(2014) Ana Ferreira   Frontiers in Cellular Neuroscience

A gene variant in the Atp10d gene associates with atherosclerotic indices in Japanese elderly population

(2013) James Tumaini Kengia et al.   ATHEROSCLEROSIS

Cell adhesion and intracellular calcium signaling in neurons

(2013) Lifu Sheng et al.   Cell Communication and Signaling

Distinct manifestations of executive dysfunction in aged rats

(2013) B. Sofia Beas et al.   NEUROBIOLOGY OF AGING

Individual variation in resisting temptation: Implications for addiction

(2013) Benjamin T. Saunders et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Ventral–striatal responsiveness during reward anticipation in ADHD and its relation to trait impulsivity in the healthy population: A meta-analytic review of the fMRI literature

(2013) Michael M. Plichta et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mechanisms of dopamine transporter regulation in normal and disease states

(2013) Roxanne A. Vaughan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Refining psychiatric phenotypes for response to treatment: Contribution of LPHN3 in ADHD

(2012) Aurelie Labbe et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Initial characterization of mice null for Lphn3 , a gene implicated in ADHD and addiction

(2012) Deeann Wallis et al.   BRAIN RESEARCH

Impact of the ADHD-susceptibility gene CDH13 on development and function of brain networks

(2012) Olga Rivero et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dances with black widow spiders: Dysregulation of glutamate signalling enters centre stage in ADHD

(2012) K.P. Lesch et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Genetics of dopamine receptors and drug addiction

(2012) Philip Gorwood et al.   HUMAN GENETICS

A common genetic network underlies substance use disorders and disruptive or externalizing disorders

(2012) Mauricio Arcos-Burgos et al.   HUMAN GENETICS

Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence

(2012) Joanna M. Biernacka et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancy

(2012) Zia Choudhry et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Striatal Sensitivity During Reward Processing in Attention-Deficit/Hyperactivity Disorder

(2012) Yannis Paloyelis et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

The ADHD-susceptibility gene lphn3.1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development

(2012) M Lange et al.   MOLECULAR PSYCHIATRY

FLRT Proteins Are Endogenous Latrophilin Ligands and Regulate Excitatory Synapse Development

(2012) Matthew L. O'Sullivan et al.   NEURON

The Mysterious Motivational Functions of Mesolimbic Dopamine

(2012) John D. Salamone et al.   NEURON

Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13)

(2012) Amy B. Hart et al.   PLoS One

Vitamin D and Calcium Status in South African Adolescents with Alcohol Use Disorders

(2012) Celeste E. Naude et al.   Nutrients

Integrated Genome-Wide Association Study Findings: Identification of a Neurodevelopmental Network for Attention Deficit Hyperactivity Disorder

(2011) Geert Poelmans et al.   AMERICAN JOURNAL OF PSYCHIATRY

Addiction Circuitry in the Human Brain

(2011) Nora D. Volkow et al.   Annual Review of Pharmacology and Toxicology

Atypical Prefrontal Connectivity in Attention-Deficit/Hyperactivity Disorder: Pathway to Disease or Pathological End Point?

(2011) Conor Liston et al.   BIOLOGICAL PSYCHIATRY

Homeostatic Synaptic Plasticity through Changes in Presynaptic Calcium Influx

(2011) C. Zhao et al.   JOURNAL OF NEUROSCIENCE

Runx1 promotes neuronal differentiation in dorsal root ganglion

(2011) Azusa Kobayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD

(2011) M Jain et al.   MOLECULAR PSYCHIATRY

SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism

(2011) C M Durand et al.   MOLECULAR PSYCHIATRY

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Expression and localization of the iron–siderophore binding protein lipocalin 2 in the normal rat brain and after kainate-induced excitotoxicity

(2011) Wan-Jie Chia et al.   NEUROCHEMISTRY INTERNATIONAL

Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation

(2011) M. Mucha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Association Studies of Alcohol Dependence and Substance Use Disorders

(2011) Jens Treutlein et al.   Current Psychiatry Reports

A two-locus genetic interaction between LPHN3 and 11q predicts ADHD severity and long-term outcome

(2011) M T Acosta et al.   Translational Psychiatry

Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility

(2010) Sabina Domené et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

From the black widow spider to human behavior: Latrophilins, a relatively unknown class of G protein-coupled receptors, are implicated in psychiatric disorders

(2010) Ariel F. Martinez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Dissociable regulation of instrumental action within mouse prefrontal cortex

(2010) Shannon L. Gourley et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Contribution of LPHN3 to the genetic susceptibility to ADHD in adulthood: a replication study

(2010) M. Ribasés et al.   GENES BRAIN AND BEHAVIOR

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

(2010) M Arcos-Burgos et al.   MOLECULAR PSYCHIATRY

Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway

(2010) N D Volkow et al.   MOLECULAR PSYCHIATRY

Long-lasting sensitization of reward-directed behavior by amphetamine

(2009) Ian A. Mendez et al.   BEHAVIOURAL BRAIN RESEARCH

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Use of latency to immobility improves detection of antidepressant-like activity in the behavioral despair test in the mouse

(2009) Vincent Castagné et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Primary support cultures of hippocampal and substantia nigra neurons

(2009) Thomas Fath et al.   Nature Protocols

New insights into the genetics of addiction

(2009) Ming D. Li et al.   NATURE REVIEWS GENETICS

New insights into attention-deficit/hyperactivity disorder using structural neuroimaging

(2009) Philip Shaw et al.   Current Psychiatry Reports

Genome-Wide Association for Methamphetamine Dependence

(2008) George R. Uhl et al.   ARCHIVES OF GENERAL PSYCHIATRY

Neurodevelopmental Trajectories of the Human Cerebral Cortex

(2008) P. Shaw et al.   JOURNAL OF NEUROSCIENCE

Proteomics- and Transcriptomics-Based Screening of Differentially Expressed Proteins and Genes in Brain of Wig Rat: A Model for Attention Deficit Hyperactivity Disorder (ADHD) Research

(2008) Misato Hirano et al.   JOURNAL OF PROTEOME RESEARCH

“Higher order” addiction molecular genetics: Convergent data from genome-wide association in humans and mice

(2007) George R. Uhl et al.   BIOCHEMICAL PHARMACOLOGY

Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?

(2007) Joyce C. McCann et al.   FASEB JOURNAL