Cancer Cells with Alternative Lengthening of Telomeres Do Not Display a General Hypersensitivity to ATR Inhibition

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

(2016) Carl Koschmann et al.   Science Translational Medicine

Role of Telomeres and Telomerase in Aging and Cancer

(2016) J. W. Shay   Cancer Discovery

PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening

(2015) S. Osterwald et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms of activity and derepression of alternative lengthening of telomeres

(2015) Hilda A Pickett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors

(2015) R. L. Flynn et al.   SCIENCE

Emerging roles of ATRX in cancer

(2015) L Ashley Watson et al.   Epigenomics

Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX

(2015) David Clynes et al.   Nature Communications

Molecular mechanisms of activity and derepression of alternative lengthening of telomeres

(2015) Hilda A Pickett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATRX represses alternative lengthening of telomeres

(2015) Christine E. Napier et al.   Oncotarget

Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1

(2014) Roderick J O'Sullivan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative lengthening of telomeres: remodeling the telomere architecture

(2013) Dimitri Conomos et al.   Frontiers in Oncology

Functional significance of mutations in the Snf2 domain of ATRX

(2011) Matthew Mitson et al.   HUMAN MOLECULAR GENETICS

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

(2011) Philip M Reaper et al.   Nature Chemical Biology

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

A Mutant Allele of MRE11 Found in Mismatch Repair-deficient Tumor Cells Suppresses the Cellular Response to DNA Replication Fork Stress in a Dominant Negative Manner

(2008) Qin Wen et al.   MOLECULAR BIOLOGY OF THE CELL