Marked changes in dendritic structure and spine density precede significant neuronal death in vulnerable cortical pyramidal neuron populations in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Glycinergic Neurotransmission: A Potent Regulator of Embryonic Motor Neuron Dendritic Morphology and Synaptic Plasticity

(2016) M. J. Fogarty et al.   JOURNAL OF NEUROSCIENCE

Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia

(2016) Ann Van der Jeugd et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Prolonged Consumption of Sucrose in a Binge-Like Manner, Alters the Morphology of Medium Spiny Neurons in the Nucleus Accumbens Shell

(2016) Paul M. Klenowski et al.   Frontiers in Behavioral Neuroscience

Developmental changes in the morphology of mouse hypoglossal motor neurons

(2015) Refik Kanjhan et al.   Brain Structure & Function

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function

(2015) Javier H. Jara et al.   CEREBRAL CORTEX

Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis

(2015) L. Saba et al.   CEREBRAL CORTEX

Increased anxiety-like behavior and selective learning impairments are concomitant to loss of hippocampal interneurons in the presymptomatic SOD1(G93A) ALS mouse model

(2015) Eros Quarta et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The cognitive profile of ALS: a systematic review and meta-analysis update

(2015) Emma Beeldman et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Structural and functional characterization of dendritic arbors and GABAergic synaptic inputs on interneurons and principal cells in the rat basolateral amygdala

(2015) Paul M. Klenowski et al.   JOURNAL OF NEUROPHYSIOLOGY

Motor Cortex Layer V Pyramidal Neurons Exhibit Dendritic Regression, Spine Loss, and Increased Synaptic Excitation in the Presymptomatic hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

(2015) M. J. Fogarty et al.   JOURNAL OF NEUROSCIENCE

End-of-life management in patients with amyotrophic lateral sclerosis

(2015) Sheelah Connolly et al.   LANCET NEUROLOGY

Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron

(2015) Srikanth Ramaswamy et al.   Frontiers in Cellular Neuroscience

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

(2015) Anna-Claire Devlin et al.   Nature Communications

Cortical Function in Asymptomatic Carriers and Patients WithC9orf72Amyotrophic Lateral Sclerosis

(2015) Nimeshan Geevasinga et al.   JAMA Neurology

Connectome and Maturation Profiles of the Developing Mouse Brain Using Diffusion Tensor Imaging

(2014) Madhura Ingalhalikar et al.   CEREBRAL CORTEX

Longitudinal course of cortical thickness decline in amyotrophic lateral sclerosis

(2014) Christina Schuster et al.   JOURNAL OF NEUROLOGY

Regional alterations in cortical thickness and white matter integrity in amyotrophic lateral sclerosis

(2014) Jiuquan Zhang et al.   JOURNAL OF NEUROLOGY

Cortical thickness in ALS: towards a marker for upper motor neuron involvement

(2014) R. Walhout et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Amyotrophic lateral sclerosis: a long preclinical period?

(2014) A. Eisen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis

(2014) Félix Leroy et al.   eLife

Extent of cortical involvement in amyotrophic lateral sclerosis – an analysis based on cortical thickness

(2013) Johannes Thorns et al.   BMC Neurology

Growth Hormone Secretion Is Correlated With Neuromuscular Innervation Rather Than Motor Neuron Number in Early-Symptomatic Male Amyotrophic Lateral Sclerosis Mice

(2013) F. J. Steyn et al.   ENDOCRINOLOGY

Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis

(2013) John D Lee et al.   Journal of Neuroinflammation

Focal thinning of the motor cortex mirrors clinical features of amyotrophic lateral sclerosis and their phenotypes: a neuroimaging study

(2013) Christina Schuster et al.   JOURNAL OF NEUROLOGY

eGFP Expression under UCHL1 Promoter Genetically Labels Corticospinal Motor Neurons and a Subpopulation of Degeneration-Resistant Spinal Motor Neurons in an ALS Mouse Model

(2013) M. V. Yasvoina et al.   JOURNAL OF NEUROSCIENCE

Controversies and priorities in amyotrophic lateral sclerosis

(2013) Martin R Turner et al.   LANCET NEUROLOGY

Embryonic alteration of motoneuronal morphology induces hyperexcitability in the mouse model of amyotrophic lateral sclerosis

(2013) Elodie Martin et al.   NEUROBIOLOGY OF DISEASE

Motor cortex microcircuits

(2013) Michael Brecht et al.   Frontiers in Neural Circuits

Different scaling of white matter volume, cortical connectivity, and gyrification across rodent and primate brains

(2013) Lissa Ventura-Antunes et al.   Frontiers in Neuroanatomy

Amyotrophic Lateral Sclerosis and Excitotoxicity: From Pathological Mechanism to Therapeutic Target

(2012) E. Bogaert et al.   CNS & Neurological Disorders-Drug Targets

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

(2012) Brigitte van Zundert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS

(2012) Javier H. Jara et al.   NEUROBIOLOGY OF DISEASE

Postnatal dendritic development in lumbar motoneurons in mutant superoxide dismutase 1 mouse model of amyotrophic lateral sclerosis

(2012) A.A. Filipchuk et al.   NEUROSCIENCE

The Cortical Signature of Amyotrophic Lateral Sclerosis

(2012) Federica Agosta et al.   PLoS One

Structural MRI reveals cortical thinning in amyotrophic lateral sclerosis

(2011) Esther Verstraete et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

(2011) Julie Phukan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Corticospinal Motor Neurons and Related Subcerebral Projection Neurons Undergo Early and Specific Neurodegeneration in hSOD1G93A Transgenic ALS Mice

(2011) P. H. Ozdinler et al.   JOURNAL OF NEUROSCIENCE

Clinical diagnosis and management of amyotrophic lateral sclerosis

(2011) Orla Hardiman et al.   Nature Reviews Neurology

Proportional neuronal loss between the primary motor and sensory cortex in amyotrophic lateral sclerosis

(2011) Yoko Mochizuki et al.   NEUROSCIENCE LETTERS

Local Connections of Layer 5 GABAergic Interneurons to Corticospinal Neurons

(2011) Yasuyo H. Tanaka et al.   Frontiers in Neural Circuits

Morphological Development of Thick-Tufted Layer V Pyramidal Cells in the Rat Somatosensory Cortex

(2011) Sandrine Romand et al.   Frontiers in Neuroanatomy

Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models

(2010) Jennifer I. Luebke et al.   Brain Structure & Function

Postsynaptic Alteration of NR2A Subunit and Defective Autophosphorylation of alphaCaMKII at Threonine-286 Contribute to Abnormal Plasticity and Morphology of Upper Motor Neurons in Presymptomatic SOD1G93A Mice, a Murine Model for Amyotrophic Lateral Sclerosis

(2010) A. Spalloni et al.   CEREBRAL CORTEX

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice

(2009) Arnaud Pambo-Pambo et al.   JOURNAL OF NEUROPHYSIOLOGY

Detection of motor cortex thinning and corticospinal tract involvement by quantitative MRI in amyotrophic lateral sclerosis

(2008) Luca Roccatagliata et al.   Amyotrophic Lateral Sclerosis

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

(2008) Steve Vucic et al.   BRAIN

Abnormal medial prefrontal cortex connectivity and defective fear extinction in the presymptomatic G93A SOD1 mouse model of ALS

(2008) C. Sgobio et al.   GENES BRAIN AND BEHAVIOR

Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice

(2008) Julien Amendola et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

(2008) B. van Zundert et al.   JOURNAL OF NEUROSCIENCE

Top-down laminar organization of the excitatory network in motor cortex

(2008) Nicholas Weiler et al.   NATURE NEUROSCIENCE

Pyramidal neurons: dendritic structure and synaptic integration

(2008) Nelson Spruston   NATURE REVIEWS NEUROSCIENCE