Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis

ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation

(2014) R. Seijffers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis

(2013) Steve Vucic et al.   BRAIN

Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

(2013) Lydie Morel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organization of Cortical and Thalamic Input to Pyramidal Neurons in Mouse Motor Cortex

(2013) B. M. Hooks et al.   JOURNAL OF NEUROSCIENCE

Corticostriatal connectivity and its role in disease

(2013) Gordon M. G. Shepherd   NATURE REVIEWS NEUROSCIENCE

Synaptic Computation and Sensory Processing in Neocortical Layer 2/3

(2013) Carl C.H. Petersen et al.   NEURON

Structural and Functional Analysis of Human SOD1 in Amyotrophic Lateral Sclerosis

(2013) Lorenna Giannini Alves Moreira et al.   PLoS One

The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments

(2013) Karina D. Thielsen et al.   PLoS One

Diversity of layer 5 projection neurons in the mouse motor cortex

(2013) Manfred J. Oswald et al.   Frontiers in Cellular Neuroscience

Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis

(2012) Alida Spalloni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fluoxetine suppresses synaptically induced [Ca2+]i spikes and excitotoxicity in cultured rat hippocampal neurons

(2012) Hee Jung Kim et al.   BRAIN RESEARCH

Intrinsic Electrophysiology of Mouse Corticospinal Neurons: a Class-Specific Triad of Spike-Related Properties

(2012) B. A. Suter et al.   CEREBRAL CORTEX

Amyotrophic Lateral Sclerosis and Excitotoxicity: From Pathological Mechanism to Therapeutic Target

(2012) E. Bogaert et al.   CNS & Neurological Disorders-Drug Targets

Over-expression of N-type calcium channels in cortical neurons from a mouse model of Amyotrophic Lateral Sclerosis

(2012) Massimo Pieri et al.   EXPERIMENTAL NEUROLOGY

Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights

(2012) Steve Vucic et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cortical excitability distinguishes ALS from mimic disorders

(2011) Steve Vucic et al.   CLINICAL NEUROPHYSIOLOGY

Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2

(2011) Emily Foran et al.   GLIA

The BH4 domain of Bcl-XL rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals

(2011) Francesca Martorana et al.   HUMAN MOLECULAR GENETICS

Effect of prolonged riluzole exposure on cultured motoneurons in a mouse model of ALS

(2011) J. E. Schuster et al.   JOURNAL OF NEUROPHYSIOLOGY

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

(2011) Thomas Philips et al.   LANCET NEUROLOGY

Respiration and ROS production in brain and spinal cord mitochondria of transgenic rats with mutant G93a Cu/Zn-superoxide dismutase gene

(2011) Alexander Panov et al.   NEUROBIOLOGY OF DISEASE

A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis

(2010) Mamede de Carvalho et al.   Amyotrophic Lateral Sclerosis

Reduced GABAergic Inhibition Explains Cortical Hyperexcitability in the Wobbler Mouse Model of ALS

(2010) Jose Luis Nieto-Gonzalez et al.   CEREBRAL CORTEX

Postsynaptic Alteration of NR2A Subunit and Defective Autophosphorylation of alphaCaMKII at Threonine-286 Contribute to Abnormal Plasticity and Morphology of Upper Motor Neurons in Presymptomatic SOD1G93A Mice, a Murine Model for Amyotrophic Lateral Sclerosis

(2010) A. Spalloni et al.   CEREBRAL CORTEX

Amyotrophic Lateral Sclerosis

(2010) Paul H. Gordon   CNS DRUGS

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

(2010) B.C. Cheah et al.   CURRENT MEDICINAL CHEMISTRY

Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture

(2010) Irene Carunchio et al.   EXPERIMENTAL NEUROLOGY

Glutamate Transporters and the Excitotoxic Path to Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis

(2009) Emily Foran et al.   ANTIOXIDANTS & REDOX SIGNALING

Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia

(2009) Akihito Uezato et al.   BIPOLAR DISORDERS

Reduced VGLUT2 expression increases motor neuron viability in Sod1G93A mice

(2009) Hanna Wootz et al.   NEUROBIOLOGY OF DISEASE

Amyotrophic lateral sclerosis

(2009) Lokesh C Wijesekera et al.   Orphanet Journal of Rare Diseases

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

(2008) Steve Vucic et al.   BRAIN

Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis

(2008) Massimo Pieri et al.   EXPERIMENTAL NEUROLOGY

Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice

(2008) Julien Amendola et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse

(2008) Alessandro Graziano et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

(2008) B. van Zundert et al.   JOURNAL OF NEUROSCIENCE

Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

(2008) Rebecca P. Seal et al.   NEURON

Structural Homeostasis: Compensatory Adjustments of Dendritic Arbor Geometry in Response to Variations of Synaptic Input

(2008) Marco Tripodi et al.   PLOS BIOLOGY

Antipsychotics increase vesicular glutamate transporter 2 (VGLUT2) expression in thalamolimbic pathways

(2007) Larissa Moutsimilli et al.   NEUROPHARMACOLOGY