Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

(2016) Hansen Lui et al.   CELL

Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer’s Disease: Comparison and Contrast with Microtubule-Associated Protein Tau

(2016) Kenneth Hensley et al.   JOURNAL OF ALZHEIMERS DISEASE

Frontotemporal Lobar Degeneration and MicroRNAs

(2016) Paola Piscopo et al.   Frontiers in Aging Neuroscience

Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy

(2016) Roya Behrouzi et al.   Acta Neuropathologica Communications

miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregationin vivo

(2015) Pascal Y. Smith et al.   HUMAN MOLECULAR GENETICS

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

(2015) Ismael Santa-Maria et al.   JOURNAL OF CLINICAL INVESTIGATION

The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels

(2015) D. A. Salazar et al.   JOURNAL OF NEUROSCIENCE

Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

(2015) Maxime Derisbourg et al.   Scientific Reports

New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications

(2014) L. Chare et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Motor and cognitive deficits in aged tau knockout mice in two background strains

(2014) Peng Lei et al.   Molecular Neurodegeneration

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

(2014) Tariq Ahmed et al.   NEUROBIOLOGY OF AGING

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

(2014) Simon Dujardin et al.   PLoS One

Progranulin in neurodegenerative disease

(2014) Terri L. Petkau et al.   TRENDS IN NEUROSCIENCES

A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

(2014) Marie Violet et al.   Frontiers in Cellular Neuroscience

Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, But Not in Glutamate Transporter-1, in the Prefrontal Cortex

(2013) Magdalena Kulijewicz-Nawrot et al.   ASN Neuro

Hyposmolality differentially and spatiotemporally modulates levels of glutamine synthetase and serine racemase in rat supraoptic nucleus

(2013) Yu-Feng Wang et al.   GLIA

Glutamate Metabolism is Impaired in Transgenic Mice with Tau Hyperphosphorylation

(2013) Linn Hege Nilsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

(2012) Katherine R. Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fyn Kinases Play a Critical Role in Neuronal Apoptosis Induced by Oxygen and Glucose Deprivation or Amyloid-β Peptide Treatment

(2012) Cai-Ping Du et al.   CNS Neuroscience & Therapeutics

Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated byN-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation

(2012) Siddhartha Mondragón-Rodríguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration

(2012) Basar Cenik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progranulin regulates neuronal outgrowth independent of Sortilin

(2012) Jennifer Gass et al.   Molecular Neurodegeneration

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

(2012) Peng Lei et al.   NATURE MEDICINE

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

(2012) Y. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced Pluripotent Stem Cell Models of Progranulin-Deficient Frontotemporal Dementia Uncover Specific Reversible Neuronal Defects

(2012) Sandra Almeida et al.   Cell Reports

Motor Neuron dysfunction in frontotemporal dementia

(2011) James R. Burrell et al.   BRAIN

Progranulin Deficiency Decreases Gross Neural Connectivity But Enhances Transmission at Individual Synapses

(2011) L. Tapia et al.   JOURNAL OF NEUROSCIENCE

Classification of primary progressive aphasia and its variants

(2011) M. L. Gorno-Tempini et al.   NEUROLOGY

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

(2011) Alan E. Renton et al.   NEURON

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

(2010) Hazel Urwin et al.   ACTA NEUROPATHOLOGICA

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Frontotemporal Lobar Degeneration

(2010) Gil D. Rabinovici et al.   CNS DRUGS

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

Nuclear Tau, a Key Player in Neuronal DNA Protection

(2010) Audrey Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progranulin expression in the developing and adult murine brain

(2010) Terri L. Petkau et al.   JOURNAL OF COMPARATIVE NEUROLOGY

TAR DNA-binding protein 43 in neurodegenerative disease

(2010) Alice S. Chen-Plotkin et al.   Nature Reviews Neurology

Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene

(2009) Ida Elisabeth Holm et al.   ACTA NEUROPATHOLOGICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

A new subtype of frontotemporal lobar degeneration with FUS pathology

(2009) M. Neumann et al.   BRAIN

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations

(2008) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Distinct genetic forms of frontotemporal dementia

(2008) H. Seelaar et al.   NEUROLOGY

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE