Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

(2015) David Castel et al.   ACTA NEUROPATHOLOGICA

Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas

(2015) Stephanie Puget et al.   CHILDS NERVOUS SYSTEM

Mutational landscape and clonal architecture in grade II and III gliomas

(2015) Hiromichi Suzuki et al.   NATURE GENETICS

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

(2015) Catherine S Grasso et al.   NATURE MEDICINE

From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity

(2015) Marc Aubry et al.   Oncotarget

A standardized autopsy procurement allows for the comprehensive study of DIPG biology

(2015) Madhuri Kambhampati et al.   Oncotarget

Subventricular spread of diffuse intrinsic pontine glioma

(2014) Viola Caretti et al.   ACTA NEUROPATHOLOGICA

Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications

(2014) Pawel Buczkowicz et al.   ACTA NEUROPATHOLOGICA

Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas

(2014) Kathleen Dorris et al.   JOURNAL OF NEURO-ONCOLOGY

Diffuse intrinsic pontine glioma: a reassessment

(2014) Nathan J. Robison et al.   JOURNAL OF NEURO-ONCOLOGY

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

(2014) Pawel Buczkowicz et al.   NATURE GENETICS

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

(2014) Kathryn R Taylor et al.   NATURE GENETICS

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

(2014) Adam M Fontebasso et al.   NATURE GENETICS

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

(2014) Rintaro Hashizume et al.   NATURE MEDICINE

Diffuse intrinsic pontine glioma biopsy: A single institution experience

(2014) Zhihong J. Wang et al.   PEDIATRIC BLOOD & CANCER

Time to rethink the unthinkable: Upfront biopsy of children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)

(2014) Mark W. Kieran   PEDIATRIC BLOOD & CANCER

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas

(2013) B. S. Paugh et al.   CANCER RESEARCH

Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma

(2013) A. Broniscer et al.   CLINICAL CANCER RESEARCH

H3F3A K27M mutations in thalamic gliomas from young adult patients

(2013) Koki Aihara et al.   NEURO-ONCOLOGY

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

(2013) A. Sottoriva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

(2012) Dong-Anh Khuong-Quang et al.   ACTA NEUROPATHOLOGICA

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Mesenchymal Transition and PDGFRA Amplification/Mutation Are Key Distinct Oncogenic Events in Pediatric Diffuse Intrinsic Pontine Gliomas

(2012) Stephanie Puget et al.   PLoS One

Diffuse intrinsic pontine gliomas: A systematic update on clinical trials and biology

(2011) M.H.A. Jansen et al.   CANCER TREATMENT REVIEWS

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Prospective collection of tissue samples at autopsy in children with diffuse intrinsic pontine glioma

(2010) Alberto Broniscer et al.   CANCER

Prospective neuraxis MRI surveillance reveals a high risk of leptomeningeal dissemination in diffuse intrinsic pontine glioma

(2010) Rajni Sethi et al.   JOURNAL OF NEURO-ONCOLOGY