Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis
Authors
Keywords
-
Journal
Nature Microbiology
Volume 1, Issue 3, Pages 15034
Publisher
Springer Nature
Online
2016-02-23
DOI
10.1038/nmicrobiol.2015.34
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis
- (2015) Gregor Ebert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy
- (2015) Joel D. Leverson et al. Science Translational Medicine
- Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity
- (2014) Zhi-Fu Tao et al. ACS Medicinal Chemistry Letters
- The Dot/Icm Effector SdhA Is Necessary for Virulence of Legionella pneumophila in Galleria mellonella and A/J Mice
- (2013) Clare R. Harding et al. INFECTION AND IMMUNITY
- Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR
- (2013) Stanimir S Ivanov et al. NATURE IMMUNOLOGY
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis
- (2013) T. Okamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Host Translation at the Nexus of Infection and Immunity
- (2012) Ian Mohr et al. Cell Host & Microbe
- Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans
- (2012) Deborah L. McEwan et al. Cell Host & Microbe
- Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen
- (2012) T. J. O'Connor et al. SCIENCE
- Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
- (2011) Andreas Strasser et al. EMBO JOURNAL
- Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1
- (2011) Ben A. Croker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila
- (2011) Mary F. Fontana et al. PLoS Pathogens
- Comparative and Functional Genomics of Legionella Identified Eukaryotic Like Proteins as Key Players in Host?Pathogen Interactions
- (2011) Laura Gomez-Valero et al. Frontiers in Microbiology
- Molecular Pathogenesis of Infections Caused by Legionella pneumophila
- (2010) H. J. Newton et al. CLINICAL MICROBIOLOGY REVIEWS
- Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease
- (2010) Christel Cazalet et al. PLoS Genetics
- Targeting eEF1A by aLegionella pneumophilaeffector leads to inhibition of protein synthesis and induction of host stress response
- (2009) Xihui Shen et al. CELLULAR MICROBIOLOGY
- Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
- (2009) F. G. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Experimental Legionella longbeachae infection in intratracheally inoculated mice
- (2009) I. Gobin et al. JOURNAL OF MEDICAL MICROBIOLOGY
- Rapid Pathogen-Induced Apoptosis: A Mechanism Used by Dendritic Cells to Limit Intracellular Replication of Legionella pneumophila
- (2009) Catarina V. Nogueira et al. PLoS Pathogens
- ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
- (2008) C. Tse et al. CANCER RESEARCH
- BCL-2 family antagonists for cancer therapy
- (2008) Guillaume Lessene et al. NATURE REVIEWS DRUG DISCOVERY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now