Review
Food Science & Technology
Qianyu Qu, Penggang He, Yuqi Zhang, Shujuan Yang, Peibin Zeng
Summary: Probiotics have shown beneficial effects in the treatment of type 2 diabetes, especially in animal models. However, the translation of these findings to humans is limited by the differences between experimental animal models and humans.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Review
Food Science & Technology
Tingting Liang, Lei Wu, Yu Xi, Ying Li, Xinqiang Xie, Congcong Fan, Lingshuang Yang, Shuanghong Yang, Xuefeng Chen, Jumei Zhang, Qingping Wu
Summary: This meta-analysis demonstrates that probiotics supplementation significantly improves glycemic, lipid, blood pressure, and inflammation control in type 2 diabetes patients, especially for those within certain age and BMI ranges, and with longer duration of probiotics supplementation.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Endocrinology & Metabolism
Teresa Buckner, Lauren A. Vanderlinden, Brian C. DeFelice, Patrick M. Carry, Katerina Kechris, Fran Dong, Oliver Fiehn, Brigitte I. Frohnert, Michael Clare-Salzler, Marian Rewers, Jill M. Norris
Summary: The study found that some oxylipins are associated with an increased risk of type 1 diabetes, while others are associated with a decreased risk. Higher levels of linoleic acid and alpha-linolenic acid-related oxylipins demonstrate a protective association in reducing the risk of type 1 diabetes.
Article
Biochemistry & Molecular Biology
Xianrong Zhou, Guan-sheng Shang, Qian Tan, Qin He, Xiaoyu Tan, Kun-Young Park, Xin Zhao
Summary: L. fermentum TKSN041 shows potential preventive and therapeutic effects on type 2 diabetes in rats, reducing water intake, controlling blood glucose levels, decreasing harmful substances, and protecting organ functions.
Review
Biochemistry & Molecular Biology
Jinjoo Lee, Seungjin Noh, Suhyun Lim, Bonglee Kim
Summary: Type 2 diabetes mellitus is a major global public health issue, with plant extracts being a potential therapeutic agent due to their antidiabetic effects and fewer side effects. These extracts regulate blood glucose, possess anti-inflammatory and antioxidant properties, and can alleviate complications caused by insulin resistance through various pathways.
Article
Chemistry, Medicinal
Chaiyavat Chaiyasut, Bhagavathi Sundaram Sivamaruthi, Narissara Lailerd, Sasithorn Sirilun, Subramanian Thangaleela, Suchanat Khongtan, Muruganantham Bharathi, Periyanaina Kesika, Manee Saelee, Thiwanya Choeisoongnern, Pranom Fukngoen, Sartjin Peerajan, Phakkharawat Sittiprapaporn
Summary: Type 2 diabetes is a prevalent metabolic disorder with various health threats. This study investigated the effects of Bifidobacterium breve supplementation on glycemic control, lipid profile, and microbiome in subjects with type 2 diabetes.
Article
Biotechnology & Applied Microbiology
Zhonghui Gai, Wenyan Liao, Yue Huang, Yao Dong, Huafeng Feng, Mei Han
Summary: Gut dysbiosis is linked to damage to the intestinal barrier and type 2 diabetes mellitus (T2DM). This study investigated the protective effects of probiotic strains BL21 and LRa05 on gut microbiota in T2DM mice and their potential modulation of the gut microbiota. The administration of BL21 and LRa05 strains significantly regulated blood glucose levels and reduced oxidative stress in the mice. Microbiota analysis revealed distinct spatial distributions of cecal and fecal microbiota, and the intervention with BL21 and LRa05 had significant effects on the cecal and fecal microbiota structure. The study highlights the potential of probiotics in preventing or ameliorating T2DM by modulating the intestinal flora and reducing inflammation and oxidative stress, emphasizing the importance of targeting multiple intestinal sites in T2DM intervention.
Article
Food Science & Technology
Parichart Toejing, Nanticha Khampithum, Sasithorn Sirilun, Chaiyavat Chaiyasut, Narissara Lailerd
Summary: The probiotic L. paracasei HII01 showed effectiveness in improving glycemia and reducing inflammatory markers in T2DM patients, likely by modifying gut microbiota to ameliorate leaky gut and endotoxemia.
Article
Endocrinology & Metabolism
Qiuxia Min, Yan Wang, TaiCheng Jin, Lei Zhu, XianYan Wu, YiKun Li, YanJiao Wang, Ning Xu
Summary: This study investigates the therapeutic effect of probiotics on type 2 diabetes mellitus and its regulatory effect on short-chain fatty acids, which are metabolites of intestinal microorganisms. The results demonstrate that both probiotics and GLP-1 treatment can improve blood glucose levels, urine glucose, and BMI in patients with type 2 diabetes. The study also reveals changes in intestinal short-chain fatty acids after probiotics or GLP-1 treatment, suggesting potential intervention targets for diabetes treatment.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yu-Hui Tang, Yeh-Han Wang, Chin-Chang Chen, Chia-Jung Chan, Fuu-Jen Tsai, Shih-Yin Chen
Summary: This study investigates the expression of adiponectin in T2DM mice and explores the genetic distribution of adiponectin gene polymorphisms in a Taiwanese population. It also measures serum adiponectin protein concentrations in T2DM patients. The findings suggest that adiponectin may be involved in T2DM susceptibility and progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Samukelisiwe C. Shabalala, Rabia Johnson, Albertus K. Basson, Khanyisani Ziqubu, Nokulunga Hlengwa, Sinenhlanhla X. H. Mthembu, Sihle E. Mabhida, Sithandiwe E. Mazibuko-Mbeje, Sidney Hanser, Ilenia Cirilli, Luca Tiano, Phiwayinkosi Dludla
Summary: This review investigates the pathological relevance of elevated lipid peroxidation products in type 2 diabetes (T2D), highlighting their potential role as biomarkers and therapeutic targets. It also briefly explains the significance of antioxidant enzymes/factors involved in blocking lipid peroxidation.
Article
Chemistry, Medicinal
Samaneh Azizi, Reza Mahdavi, Majid Mobasseri, Soghra Aliasgharzadeh, Fatemeh Abbaszadeh, Mehrangiz Ebrahimi-Mameghani
Summary: The study suggests that L-citrulline supplementation may improve glucose homeostasis, certain lipid factors, and inflammatory markers in overweight and obese patients with type 2 diabetes (T2D).
PHYTOTHERAPY RESEARCH
(2021)
Article
Nutrition & Dietetics
Lulu Wang, Xue Liu, Jian Hou, Dandan Wei, Pengling Liu, Keliang Fan, Li Zhang, Luting Nie, Xing Li, Wenqian Huo, Tao Jing, Wenjie Li, Chongjian Wang, Zhenxing Mao
Summary: This study found a negative correlation between serum vitamin D and impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM), as well as a negative correlation between serum 25(OH)D-2 and total 25(OH)D levels. The lipid profile, specifically total cholesterol (TC) and triglyceride (TG), partially mediated the relationship between vitamin D and IFG or T2DM. Additionally, there were interactive effects of serum 25(OH)D-2, total 25(OH)D, and testosterone on T2DM in females.
Article
Plant Sciences
Kaixia Xu, Guang Lu, Qianjin Feng, Shuangchao Chen, Yonghui Wang
Summary: This study found that protocatechuic acid has a therapeutic effect on liver injury induced by type 2 diabetes, and the potential mechanism may be through the modulation of NF-kappa B and Wnt1/beta-catenin pathways to alleviate insulin resistance, lipid accumulation, oxidative stress, and inflammation in liver tissues.
PHARMACEUTICAL BIOLOGY
(2023)
Article
Medicine, Research & Experimental
Katarzyna Nabrdalik, Karolina Drozdz, Hanna Kwiendacz, Karolina Skonieczna-Zydecka, Igor Loniewski, Mariusz Kaczmarczyk, Agata M. Wijata, Jakub Nalepa, Frits Holleman, Max Nieuwdorp, Janusz Gumprecht
Summary: This study found that a multi-strain probiotic can alleviate gastrointestinal adverse effects in patients with type 2 diabetes and metformin intolerance, including symptoms like nausea, abdominal bloating, and abdominal pain.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Engineering, Electrical & Electronic
Mohsen Hayati, Abbas Rezaei
Summary: This paper presents the design of a novel and efficient QCA-based universal logic gate, which has a compact and efficient implementation layout and is capable of implementing multiple standard functions. Additionally, an accurate artificial neural network model is provided for quick and precise simulation of QCA circuits.
IETE JOURNAL OF RESEARCH
(2022)
Article
Computer Science, Information Systems
Salah I. Yahya, Abbas Rezaei, Leila Nouri
Summary: In this paper, a high-performance microstrip diplexer was designed and fabricated using an artificial neural network method. The diplexer has a small area, low insertion losses, and group delay, making it suitable for broadband wireless applications and energy harvesting applications.
Article
Computer Science, Hardware & Architecture
Salah I. Yahya, Abbas Rezaei, Rafaa I. Yahya
Summary: In this work, a novel adaptive neuro-fuzzy inference system (ANFIS) method is used to design and fabricate a high-performance microstrip diplexer. The designed diplexer exhibits low insertion losses, small size, and wide operating frequency range. The proposed ANFIS method shows reliability and accuracy through mathematical analysis and experimental verification.
JOURNAL OF CIRCUITS SYSTEMS AND COMPUTERS
(2022)
Article
Computer Science, Artificial Intelligence
Abbas Rezaei, Salah Yahya, Leila Noori, Mohd Haizal Jamaluddin
Summary: A novel method based on artificial neural network is proposed for designing and simulating multichannel microstrip bandpass filters. This method utilizes a multilayer perceptron neural network trained with back-propagation technique to design a high-performance microstrip quad-band bandpass filter.
NEURAL COMPUTING & APPLICATIONS
(2022)
Article
Multidisciplinary Sciences
Abbas Rezaei, Salah I. Yahya
Summary: This paper presents an efficient theoretical design approach for a very compact microstrip diplexer for modern wireless communication system applications. The proposed design utilizes coupled lines, simple transmission line, and a shunt stub to achieve a small size. The diplexer has good properties and can suppress harmonics acceptably up to 3 GHz.
ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY
(2022)
Review
Multidisciplinary Sciences
Abbas Rezaei, Salah I. Yahya, Leila Nouri
Summary: In this paper, various types of microstrip couplers are studied, focusing on their structure, performance, and design methods. These planar 4-ports passive devices transmit signals through different channels, and their miniaturization and performance improvement have always been the competition among designers. Some previously reported couplers have the advantage of proposing a novel structure. A high-performance coupler should possess high isolation and low losses in both channels, as well as a low common port return loss in the pass band. Couplers with balanced amplitude and phase are more popular, and mathematical analysis methods include even/odd mode analysis, information extraction from the ABCD matrix, and analysis of the equivalent LC circuit of a simple resonator. Couplers are classified based on the phase shift value, with some having filtering and harmonic elimination features that surpass others. Setting the operating frequency according to the application type makes the coupler particularly valuable.
ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY
(2023)
Article
Engineering, Electrical & Electronic
Abbas Rezaei, Salah I. Yahya, Leila Nouri
Summary: In this work, novel spiral-coupled transmission lines are utilized to achieve a high-performance microstrip coupler. The proposed coupler features a novel structure, filtering frequency response, suppression of harmonics up to second harmonics, transmission poles, low losses, compact size, and good phase balance. The size of the coupler is only 82.6 mm(2) (0.004 lambda g(2)), demonstrating its excellent performance.
MICROWAVE AND OPTICAL TECHNOLOGY LETTERS
(2023)
Article
Chemistry, Analytical
Mohammad (Behdad) Jamshidi, Salah I. Yahya, Leila Nouri, Hamed Hashemi-Dezaki, Abbas Rezaei, Muhammad Akmal Chaudhary
Summary: Global concerns about environmental preservation and energy sustainability have led to the development of smart grid, edge computing, and Metaverse-based technologies. The 5G network, with its unique capabilities, is ideal for smart grid services and will rely on IoT for further advancement. This paper presents the design and evaluation of a super-efficient GSM triplexer for 5G-enabled IoT in sustainable smart grid edge computing and the Metaverse.
Article
Multidisciplinary Sciences
Mohammad (Behdad) Jamshidi, Salah I. Yahya, Leila Nouri, Hamed Hashemi-Dezaki, Abbas Rezaei, Muhammad Akmal Chaudhary
Summary: Symmetry plays a crucial role in the design of complex systems like the Metaverse Transportation System (MTS) to ensure effective collaboration among components. In the development of a microstrip diplexer for 5G-enabled IoT and MTS, maintaining symmetry is essential for achieving flat responses with low group delays. Integrating transportation technology and the Metaverse, MTS significantly enhances the efficiency and intelligence of real-world transportation systems. The inclusion of 5G-enabled IoT and sensor networks with an energy-efficient design is vital in establishing a reliable network.
Article
Engineering, Electrical & Electronic
Ahmad Ghiasi, Salah I. Yahya, Abbas Rezaei
Summary: This paper presents two new structures of silicon on insulator metal-semiconductor field effect transistors (SOI-MESFETs). By adding parallel layers of oxide and aluminium at the gate edge, a silicon well and two aluminium layers in the buried oxide part, and a silicon well and a silicon layer in the box oxide section, the proposed structures show improved breakdown voltage, maximum output power, cutoff frequency, and maximum oscillation frequency compared to the conventional MESFET structure. The results demonstrate that these structures have good performance and capability to operate at high power and high frequency.
INTERNATIONAL JOURNAL OF ELECTRONICS
(2023)
Article
Multidisciplinary Sciences
Salah I. Yahya, Farid Zubir, Leila Nouri, Fawwaz Hazzazi, Zubaida Yusoff, Muhammad Akmal Chaudhary, Maher Assaad, Abbas Rezaei, Binh Nguyen Le
Summary: This paper presents a design and fabrication method for a microstrip-based filtering branch-line coupler with a symmetrical structure, which ensures balanced power division and minimizes unwanted coupling. Based on mathematical design and optimization, the coupler operates at 5.2 GHz for WLAN and 5G applications. Experimental results validate the design and simulation, showing good agreement and demonstrating the potential of this design for high-performance microstrip-based communication systems.
Article
Multidisciplinary Sciences
Leila Nouri, Salah I. Yahya, Abbas Rezaei, Fawwaz Hazzazi, B. N. Nhu
Summary: This paper presents a novel compact microstrip diplexer based on spiral cells. The proposed resonator consists of two spiral thin lines connected to a pair of coupled lines. By mathematically analyzing the resonator, the dimensions of the final layout can be easily tuned. Two bandpass filters are designed using the analyzed resonator, and a high-performance microstrip diplexer is obtained by integrating these filters.
ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY
(2023)
Article
Computer Science, Artificial Intelligence
Saeed Haghiri, Salah I. Yahya, Abbas Rezaei, Arash Ahmadi
Summary: This study presents a hardware solution for emulating neural behavior in the human brain using neuronal cell mechanisms. The proposed model shows high accuracy and low error in reproducing the features of the original neuron model.
IEEE TRANSACTIONS ON EMERGING TOPICS IN COMPUTATIONAL INTELLIGENCE
(2023)
Article
Computer Science, Information Systems
Salah I. Yahya, Farid Zubir, Leila Nouri, Abbas Rezaei, Fawwaz Hazzazi, Muhammad Akmal Chaudhary, Maher Assaad, Zubaida Yusoff, Binh Nguyen Le
Summary: A new microstrip triplexer with a compact size of 0.007 A,g2 is proposed in this work, offering high performance in terms of wide channels, low insertion losses, and flat channels with low group delays. Mathematical analysis is carried out to eliminate harmonics and tune the resonance frequency, resulting in the suppression of harmonics above the first channel. The fabricated triplexer is suitable for 5G mid-band applications and can be used in designing high-performance RF communication systems.
Article
Computer Science, Information Systems
Salah I. Yahya, Farid Zubir, Leila Nouri, Zubaida Yusoff, Fawwaz Hazzazi, Muhammad Akmal Chaudhary, Maher Assaad, Abbas Rezaei, Binh Nguyen Le
Summary: This paper presents a compact filtering coupler using a new microstrip configuration. The coupler is optimized to improve frequency response, achieve good phase balance, and reduce losses. It operates at 1.9 GHz and has a working frequency range of 1.84 GHz to 2.11 GHz. The coupler offers low phase and magnitude imbalances, low losses, and low group delay, making it suitable for microwave components, communication, and radar systems.
