The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

(2015) Martin Peifer et al.   NATURE

Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients

(2015) Michaela Semeraro et al.   Science Translational Medicine

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

(2015) Wenqian Zhang et al.   GENOME BIOLOGY

c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis

(2014) A. Nanbakhsh et al.   BLOOD

Metalloprotease-Mediated Tumor Cell Shedding of B7-H6, the Ligand of the Natural Killer Cell-Activating Receptor NKp30

(2014) E. Schlecker et al.   CANCER RESEARCH

p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas

(2014) Daniel Dreidax et al.   HUMAN MOLECULAR GENETICS

T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy

(2014) I. Melero et al.   Cancer Discovery

Molecular Bases for the Regulation of NKG2D Ligands in Cancer

(2014) Leticia Huergo-Zapico et al.   Frontiers in Immunology

NK cells and T cells cooperate during the clinical course of colorectal cancer

(2014) Giuseppe Sconocchia et al.   OncoImmunology

Induction of B7-H6, a ligand for the natural killer cell-activating receptor NKp30, in inflammatory conditions

(2013) J. Matta et al.   BLOOD

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

(2013) N. Fiegler et al.   BLOOD

GSK3 Inhibitors Regulate MYCN mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling

(2013) D. J. Duffy et al.   MOLECULAR CANCER THERAPEUTICS

HER2/HER3 Signaling Regulates NK Cell-Mediated Cytotoxicity via MHC Class I Chain-Related Molecule A and B Expression in Human Breast Cancer Cell Lines

(2012) R. Okita et al.   JOURNAL OF IMMUNOLOGY

Ras Activation Induces Expression of Raet1 Family NK Receptor Ligands

(2012) X. V. Liu et al.   JOURNAL OF IMMUNOLOGY

Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2

(2011) S. Textor et al.   CANCER RESEARCH

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors

(2011) Tomonori Kaifu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MAD1 and its life as a MYC antagonist: An update

(2011) Bernhard Lüscher   EUROPEAN JOURNAL OF CELL BIOLOGY

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

(2011) Nicolas F Delahaye et al.   NATURE MEDICINE

Targeting MYC dependence in cancer by inhibiting BET bromodomains

(2011) J. A. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Repression of SKP2 Is Impaired in MYCN-Amplified Neuroblastoma

(2010) Daniel Muth et al.   CANCER RESEARCH

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc–Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

(2008) Jianxia Guo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance

(2008) A. M. Unni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA