Peritumoral stromal neutrophils are essential for c-Met-elicited metastasis in human hepatocellular carcinoma

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

(2016) A. Spiegel et al.   Cancer Discovery

PD-1hi Identifies a Novel Regulatory B-cell Population in Human Hepatoma That Promotes Disease Progression

(2016) X. Xiao et al.   Cancer Discovery

Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma

(2015) Rui-Xian Liu et al.   HEPATOLOGY

Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma

(2015) Xue-Feng Li et al.   JOURNAL OF HEPATOLOGY

MET is required for the recruitment of anti-tumoural neutrophils

(2015) Veronica Finisguerra et al.   NATURE

miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

(2015) Shicheng Su et al.   Nature Communications

A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis

(2014) Shicheng Su et al.   CANCER CELL

MicroRNAs control hepatocarcinogenesis by regulating hepatocyte nuclear factor 4α-inflammatory signal feedback loops

(2014) Hua Wang et al.   HEPATOLOGY

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

(2014) Ilona Kryczek et al.   IMMUNITY

B7-H1–expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets

(2014) Dong-Ming Kuang et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the HGF/MET pathway in gastric cancer

(2014) Florian Lordick   LANCET ONCOLOGY

The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNF 

(2014) M. P. Smith et al.   Cancer Discovery

Mutant KRAS–Induced Expression of ICAM-1 in Pancreatic Acinar Cells Causes Attraction of Macrophages to Expedite the Formation of Precancerous Lesions

(2014) Geou-Yarh Liou et al.   Cancer Discovery

HGF-MET signals via the MLL-ETS2 complex in hepatocellular carcinoma

(2013) Shugaku Takeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil-mediated tumour angiogenesis: Subversion of immune responses to promote tumour growth

(2013) Simon Tazzyman et al.   SEMINARS IN CANCER BIOLOGY

Cell-Autonomous and Non-Cell-Autonomous Mechanisms of HGF/MET-Driven Resistance to Targeted Therapies: From Basic Research to a Clinical Perspective

(2013) S. Corso et al.   Cancer Discovery

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Impairment of CD4+cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma

(2012) Junliang Fu et al.   HEPATOLOGY

Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions

(2012) Yan Wu et al.   HEPATOLOGY

Targeting the Hepatocyte Growth Factor–cMET Axis in Cancer Therapy

(2012) George R. Blumenschein et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-Recruited Neutrophils and Neutrophil TIMP-Free MMP-9 Regulate Coordinately the Levels of Tumor Angiogenesis and Efficiency of Malignant Cell Intravasation

(2011) Erin M. Bekes et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-17-educated monocytes suppress cytotoxic T-cell function through B7-H1 in hepatocellular carcinoma patients

(2011) Qiyi Zhao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma

(2011) Hanning You et al.   HEPATOLOGY

SOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes

(2011) Yirui Gui et al.   JOURNAL OF HEPATOLOGY

Activated CD69+ T Cells Foster Immune Privilege by Regulating IDO Expression in Tumor-Associated Macrophages

(2011) Q. Zhao et al.   JOURNAL OF IMMUNOLOGY

Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop

(2011) Yan Wu et al.   JOURNAL OF PATHOLOGY

MicroRNA-155 Regulates Inflammatory Cytokine Production in Tumor-associated Macrophages via Targeting C/EBPβ

(2010) Min He et al.   Cellular & Molecular Immunology

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma

(2010) Dong-Ming Kuang et al.   JOURNAL OF HEPATOLOGY

Lysophosphatidylcholine Increases Neutrophil Bactericidal Activity by Enhancement of Azurophil Granule-Phagosome Fusion via Glycine{middle dot}GlyR 2/TRPM2/p38 MAPK Signaling

(2010) C. W. Hong et al.   JOURNAL OF IMMUNOLOGY

Tumor-Activated Monocytes Promote Expansion of IL-17-Producing CD8+ T Cells in Hepatocellular Carcinoma Patients

(2010) D.-M. Kuang et al.   JOURNAL OF IMMUNOLOGY

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Yin-Yang of Tumor-Associated Neutrophils

(2009) Alberto Mantovani   CANCER CELL

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells

(2009) Dong-Ming Kuang et al.   HEPATOLOGY

Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1

(2009) Dong-Ming Kuang et al.   JOURNAL OF EXPERIMENTAL MEDICINE