Visual and Ocular Manifestations of Alzheimer’s Disease and Their Use as Biomarkers for Diagnosis and Progression

Recognition of Personally Familiar Scenes in Patients with Very Mild Alzheimer's Disease: Effects of Spatial Frequency and Luminance

(2018) Yen-Ti Lee et al.   JOURNAL OF ALZHEIMERS DISEASE

Repetitive Pupil Light Reflex: Potential Marker in Alzheimer's Disease?

(2018) Daniel M. Bittner et al.   JOURNAL OF ALZHEIMERS DISEASE

Choroidal Thinning as a New Finding in Alzheimer's Disease: Evidence from Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography

(2018) Magda Gharbiya et al.   JOURNAL OF ALZHEIMERS DISEASE

Melanopsin retinal ganglion cell loss in Alzheimer disease

(2015) Chiara La Morgia et al.   ANNALS OF NEUROLOGY

Donepezil increases contrast sensitivity for the detection of objects in scenes

(2015) Muriel Boucart et al.   BEHAVIOURAL BRAIN RESEARCH

Thinner changes of the retinal nerve fiber layer in patients with mild cognitive impairment and Alzheimer’s disease

(2015) Dachuan Liu et al.   BMC Neurology

Is amyloid-β harmful to the brain? Insights from human imaging studies

(2015) William Jagust   BRAIN

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease

(2015) K. G. Goozee et al.   BRITISH JOURNAL OF NUTRITION

Analysis of optic disk color changes in Alzheimer's disease: A potential new biomarker

(2015) Maria P. Bambo et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

A test of lens opacity as an indicator of preclinical Alzheimer Disease

(2015) Ling Bei et al.   EXPERIMENTAL EYE RESEARCH

The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis

(2015) Nienke M E Scheltens et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Alzheimer's disease and other dementias: advances in 2014

(2015) Randall Bateman   LANCET NEUROLOGY

Retinal neurodegeneration on optical coherence tomography and cerebral atrophy

(2015) Yi-Ting Ong et al.   NEUROSCIENCE LETTERS

A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration–Like Lesions at the Peripheral Retina

(2015) Imre Lengyel et al.   OPHTHALMOLOGY

Cognitive Functions and Stereopsis in Patients with Parkinson’s Disease and Alzheimer’s Disease Using 3-Dimensional Television: A Case Controlled Trial

(2015) Chan-Nyoung Lee et al.   PLoS One

Visual signs and symptoms in patients with the visual variant of Alzheimer disease

(2015) Pierre-François Kaeser et al.   BMC Ophthalmology

RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium

(2015) Sung Wook Park et al.   Oncotarget

The disengagement of visual attention in Alzheimer's disease: a longitudinal eye-tracking study

(2015) Trevor J. Crawford et al.   Frontiers in Aging Neuroscience

Optical Coherence Tomography in Alzheimer’s Disease: A Meta-Analysis

(2015) Gianluca Coppola et al.   PLoS One

Detection of retinal nerve fiber layer degeneration in patients with Alzheimer's disease using optical coherence tomography: searching new biomarkers

(2014) Maria P Bambo et al.   ACTA OPHTHALMOLOGICA

Retinal fluorescence lifetime imaging ophthalmoscopy measures depend on the severity of Alzheimer's disease

(2014) Susanne Jentsch et al.   ACTA OPHTHALMOLOGICA

RETINAL AMYLOID FLUORESCENCE IMAGING PREDICTS CEREBRAL AMYLOID BURDEN AND ALZHEIMER'S DISEASE

(2014) Shaun Frost et al.   Alzheimers & Dementia

Microvascular network alterations in the retina of patients with Alzheimer's disease

(2014) Carol Yim-lui Cheung et al.   Alzheimers & Dementia

Detection of Amyloid β Signature in the Lens and Its Correlation in the Brain to Aid in the Diagnosis of Alzheimer’s Disease

(2014) Charles Kerbage et al.   American Journal of Alzheimers Disease and Other Dementias

Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease

(2014) Malia M. Edwards et al.   EXPERIMENTAL EYE RESEARCH

Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer’s Disease (AD) and Age-Related Macular Degeneration (AMD)

(2014) Yuhai Zhao et al.   MOLECULAR NEUROBIOLOGY

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice

(2014) Sung Wook Park et al.   NEUROBIOLOGY OF AGING

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Monochromatic Pupillometry in Unilateral Glaucoma Discloses no Adaptive Changes Subserved by the ipRGCs

(2014) Claus Nissen et al.   Frontiers in Neurology

Clinical Application of 3D Arterial Spin-Labeled Brain Perfusion Imaging for Alzheimer Disease: Comparison with Brain Perfusion SPECT

(2013) H. Takahashi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Beta-Amyloid, Phospho-Tau and Alpha-Synuclein Deposits Similar to Those in the Brain Are Not Identified in the Eyes of Alzheimer's and Parkinson's Disease Patients

(2013) Cheng-Ying Ho et al.   BRAIN PATHOLOGY

Retinal amino acid neurochemistry in health and disease

(2013) Michael Kalloniatis et al.   Clinical and Experimental Optometry

Pupil Response Biomarkers Distinguish Amyloid Precursor Protein Mutation Carriers from Non-Carriers

(2013) Shaun Frost et al.   Current Alzheimer Research

Absence of amyloid-beta in lenses of Alzheimer patients: A confocal Raman microspectroscopic study

(2013) Ralph Michael et al.   EXPERIMENTAL EYE RESEARCH

Hyperphosphorylation of tau protein by calpain regulation in retina of Alzheimer's disease transgenic mouse

(2013) Haikang Zhao et al.   NEUROSCIENCE LETTERS

Changes in Amyloid-  and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein

(2013) L. F. Maia et al.   Science Translational Medicine

Unilateral Anterior Ischemic Optic Neuropathy: Chromatic Pupillometry in Affected, Fellow Non-Affected and Healthy Control Eyes

(2013) Kristina Herbst et al.   Frontiers in Neurology

Alzheimer’s Disease Diagnosis by Detecting Exogenous Fluorescent Signal of Ligand Bound to Beta Amyloid in the Lens of Human Eye: An Exploratory Study

(2013) Charles Kerbage et al.   Frontiers in Neurology

Distinct effects of inflammation on gliosis, osmohomeostasis, and vascular integrity during amyloid beta-induced retinal degeneration

(2012) Virginie Dinet et al.   AGING CELL

Antisaccades in Alzheimer's disease using fMRI

(2012) Sarah Wright et al.   Alzheimers & Dementia

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Absence of beta-amyloid in cortical cataracts of donors with and without Alzheimer's disease

(2012) Ralph Michael et al.   EXPERIMENTAL EYE RESEARCH

Retinal Nerve Fiber Layer Thickness in Patients With Alzheimer Disease

(2012) Serkan Kirbas et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

The retina as a window to the brain—from eye research to CNS disorders

(2012) Anat London et al.   Nature Reviews Neurology

Visual contrast sensitivity in Alzheimer’s disease, mild cognitive impairment, and older adults with cognitive complaints

(2012) Shannon L. Risacher et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease in the Retina: Imaging Retinal Aß Plaques for Early Diagnosis and Therapy Assessment

(2012) Yosef Koronyo et al.   Neurodegenerative Diseases

The Neuronal Organization of the Retina

(2012) Richard H. Masland   NEURON

Lateral interactions in the outer retina

(2012) Wallace B. Thoreson et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Neurodegeneration of the retina in mouse models of Alzheimer’s disease: what can we learn from the retina?

(2011) Kin Chiu et al.   AGE

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Transgenic mouse model for the formation of Hirano bodies

(2011) Sangdeuk Ha et al.   BMC NEUROSCIENCE

Retinal thickness in patients with mild cognitive impairment and Alzheimer's disease

(2011) Anat Kesler et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Imaging apoptosis in the eye

(2011) M F Cordeiro et al.   EYE

Age-related macular degeneration and the complement system

(2011) S. Khandhadia et al.   IMMUNOBIOLOGY

Complement activation as a biomarker for Alzheimer's disease

(2011) Mohammed Aiyaz et al.   IMMUNOBIOLOGY

The Architecture of Functional Interaction Networks in the Retina

(2011) E. Ganmor et al.   JOURNAL OF NEUROSCIENCE

Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma

(2011) Purushottam Jha et al.   MOLECULAR IMMUNOLOGY

CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis

(2011) Julien Bruban et al.   NEUROBIOLOGY OF DISEASE

Cataract and cognitive impairment: a review of the literature

(2010) J. M. Jefferis et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

(2010) Maya Koronyo-Hamaoui et al.   NEUROIMAGE

Retinal nerve fiber layer structure abnormalities in early Alzheimer's disease: Evidence in optical coherence tomography

(2010) Yan Lu et al.   NEUROSCIENCE LETTERS

Alzheimer's Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome

(2010) Juliet A. Moncaster et al.   PLoS One

Distinct visual motion processing impairments in aging and Alzheimer’s disease

(2010) Voyko Kavcic et al.   VISION RESEARCH

Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo

(2010) M F Cordeiro et al.   Cell Death & Disease

Amyloid-β(1-42) alters structure and function of retinal pigmented epithelial cells

(2009) Julien Bruban et al.   AGING CELL

Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice

(2009) Bingqian Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Color Discrimination Performance in Patients with Alzheimer’s Disease

(2009) Giovanna Salamone et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease

(2009) R. Michael Dutescu et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Amyloid-β up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration

(2009) Jiying Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Selective Cortical Layering Abnormalities and Behavioral Deficits in Cortex-Specific Pax6 Knock-Out Mice

(2009) T. C. Tuoc et al.   JOURNAL OF NEUROSCIENCE

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: Effects on axonal viability

(2009) Laura Gasparini et al.   NEUROBIOLOGY OF AGING

Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease

(2008) Siobhan Garbutt et al.   BRAIN

Reduced retinal function in amyloid precursor protein-over-expressing transgenic mice via attenuating glutamate-N-methyl-d-aspartate receptor signaling

(2008) Masamitsu Shimazawa et al.   JOURNAL OF NEUROCHEMISTRY

Targeting age-related macular degeneration with Alzheimer’s disease based immunotherapies: Anti-amyloid-β antibody attenuates pathologies in an age-related macular degeneration mouse model

(2007) Jin-Dong Ding et al.   VISION RESEARCH