The Role of Lymphatic Endothelial Cells in Liver Injury and Tumor Development

Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver

(2016) Christoph Eckert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Anatomy of hepatic lymphatics and its implications in hepatic malignancies

(2016) Tuck Leong Yong et al.   ANZ JOURNAL OF SURGERY

Hallmarks of Tissue-Resident Lymphocytes

(2016) Xiying Fan et al.   CELL

Lymphatic vessels regulate immune microenvironments in human and murine melanoma

(2016) Amanda W. Lund et al.   JOURNAL OF CLINICAL INVESTIGATION

Liver-Resident CD103+Dendritic Cells Prime Antiviral CD8+T Cells In Situ

(2015) Peter D. Krueger et al.   JOURNAL OF IMMUNOLOGY

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

(2015) Sherin J. Rouhani et al.   Nature Communications

CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

(2015) Emma C. Mackley et al.   Nature Communications

The Complex Myeloid Network of the Liver with Diverse Functional Capacity at Steady State and in Inflammation

(2015) Christoph Eckert et al.   Frontiers in Immunology

Intrahepatic Lymphatic Invasion but not Vascular Invasion is a Major Prognostic Factor after Resection of Colorectal Cancer Liver Metastases

(2014) Renato Micelli Lupinacci et al.   WORLD JOURNAL OF SURGERY

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

(2014) M. A. Swartz   Cancer Immunology Research

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL

(2013) Hwee Ying Lim et al.   Cell Metabolism

Characterization of the liver-draining lymph nodes in mice and their role in mounting regional immunity to HBV

(2013) Meijuan Zheng et al.   Cellular & Molecular Immunology

Atherosclerosis and Transit of HDL Through the Lymphatic Vasculature

(2013) Catherine Martel et al.   Current Atherosclerosis Reports

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

(2013) Catherine Martel et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic cells in liver injury and fibrosis: Shortcomings and promises

(2013) Veronika Lukacs-Kornek et al.   JOURNAL OF HEPATOLOGY

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

(2013) Li-Rung Huang et al.   NATURE IMMUNOLOGY

Two lymph nodes draining the mouse liver are the preferential site of DC migration and T cell activation

(2012) Louise Barbier et al.   JOURNAL OF HEPATOLOGY

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics

(2012) Amanda W. Lund et al.   Cell Reports

Association of T-Zone Reticular Networks and Conduits with Ectopic Lymphoid Tissues in Mice and Humans

(2011) Alexander Link et al.   AMERICAN JOURNAL OF PATHOLOGY

Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner

(2011) B. Vigl et al.   BLOOD

Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes

(2011) Veronika Lukacs-Kornek et al.   NATURE IMMUNOLOGY

Clinicopathological Prognostic Factors After Hepatectomy for Patients with Mass-Forming Type Intrahepatic Cholangiocarcinoma: Relevance of the Lymphatic Invasion Index

(2010) Ken Shirabe et al.   ANNALS OF SURGICAL ONCOLOGY

Lymphatic marker podoplanin/D2-40 in human advanced cirrhotic liver- Re-evaluations of microlymphatic abnormalities

(2010) Hiroaki Yokomori et al.   BMC GASTROENTEROLOGY

Self-antigen presentation by dendritic cells and lymphoid stroma and its implications for autoimmunity

(2010) Veronika Lukacs-Kornek et al.   CURRENT OPINION IN IMMUNOLOGY

A review of mast cells and liver disease: What have we learned?

(2010) Heather Francis et al.   DIGESTIVE AND LIVER DISEASE

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

(2010) Anne L. Fletcher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymphatic Patterns of Colorectal Liver Metastases

(2010) Andrew K. Hadj et al.   JOURNAL OF SURGICAL RESEARCH

Accelerated orthotopic hepatocellular carcinomas growth is linked to increased expression of pro-angiogenic and prometastatic factors in murine liver fibrosis

(2010) Miroslaw Kornek et al.   LIVER INTERNATIONAL

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

(2010) Santiago F Gonzalez et al.   NATURE IMMUNOLOGY

An Expanded Self-Antigen Peptidome Is Carried by the Human Lymph As Compared to the Plasma

(2010) Cristina C. Clement et al.   PLoS One

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

(2010) J. D. Shields et al.   SCIENCE

The lymph as a pool of self-antigens

(2010) Cristina C. Clement et al.   TRENDS IN IMMUNOLOGY

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF- B and Prox1

(2009) M. J. Flister et al.   BLOOD

Mast cell–derived particles deliver peripheral signals to remote lymph nodes

(2009) Christian A. Kunder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflamed Lymphatic Endothelium Suppresses Dendritic Cell Maturation and Function via Mac-1/ICAM-1-Dependent Mechanism

(2009) S. Podgrabinska et al.   JOURNAL OF IMMUNOLOGY

Lymph Circulation in the Liver

(2008) Osamu Ohtani et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

TGFβ-induced protein mediates lymphatic endothelial cell adhesion to the extracellular matrix under low oxygen conditions

(2008) M. Irigoyen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells

(2008) Frank A. Schildberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

VEGF-D promotes tumor growth and lymphatic spread in a mouse model of hepatocellular carcinoma

(2008) Armin Thelen et al.   INTERNATIONAL JOURNAL OF CANCER

Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice

(2008) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION