Pseudomonas aeruginosainfection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches

Does mass spectrometric breath analysis detectPseudomonas aeruginosain cystic fibrosis?

(2016) Rishi Pabary et al.   EUROPEAN RESPIRATORY JOURNAL

Defective Innate Immunity and Hyperinflammation in Newborn Cystic Fibrosis Transmembrane Conductance Regulator–Knockout Ferret Lungs

(2015) Nicholas W. Keiser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Antipseudomonal Bacteriophage Reduces Infective Burden and Inflammatory Response in Murine Lung

(2015) Rishi Pabary et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Association of meteorological and geographical factors and risk of initial Pseudomonas aeruginosa acquisition in young children with cystic fibrosis

(2015) K. J. PSOTER et al.   EPIDEMIOLOGY AND INFECTION

Pseudomonas aeruginosa and Periodontal Pathogens in the Oral Cavity and Lungs of Cystic Fibrosis Patients: a Case-Control Study

(2015) Rocio Rivas Caldas et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Proximity to blue spaces and risk of infection with Pseudomonas aeruginosa in cystic fibrosis: A case–control analysis

(2015) Pieter C. Goeminne et al.   Journal of Cystic Fibrosis

Upper aero-digestive contamination by Pseudomonas aeruginosa and implications in Cystic Fibrosis

(2015) R. Rivas Caldas et al.   Journal of Cystic Fibrosis

Pseudomonas aeruginosa genotypes acquired by children with cystic fibrosis by age 5-years

(2015) Timothy J. Kidd et al.   Journal of Cystic Fibrosis

Aspergillus fumigatusenhances elastase production inPseudomonas aeruginosaco-cultures

(2015) Karen Smith et al.   MEDICAL MYCOLOGY

Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis

(2015) Eduardo Lopez-Medina et al.   PLoS Pathogens

Pseudomonas aeruginosa inhibits the growth of Scedosporium aurantiacum, an opportunistic fungal pathogen isolated from the lungs of cystic fibrosis patients

(2015) Jashanpreet Kaur et al.   Frontiers in Microbiology

Comparison of Microbiomes from Different Niches of Upper and Lower Airways in Children and Adolescents with Cystic Fibrosis

(2015) Sébastien Boutin et al.   PLoS One

Characterization and Identification of Clinically Relevant Microorganisms Using Rapid Evaporative Ionization Mass Spectrometry

(2014) Nicole Strittmatter et al.   ANALYTICAL CHEMISTRY

Lung inflammation in cystic fibrosis: Pathogenesis and novel therapies

(2014) Barbara Dhooghe et al.   CLINICAL BIOCHEMISTRY

Pseudomonas aeruginosa in Cystic Fibrosis Patients With G551D-CFTR Treated With Ivacaftor

(2014) Sonya L. Heltshe et al.   CLINICAL INFECTIOUS DISEASES

Cyanide levels found in infected cystic fibrosis sputum inhibit airway ciliary function

(2014) C. Nair et al.   EUROPEAN RESPIRATORY JOURNAL

Predictive values of antibodies against Pseudomonas aeruginosa in patients with cystic fibrosis one year after early eradication treatment

(2014) Matthias Kappler et al.   Journal of Cystic Fibrosis

Neonates with cystic fibrosis have a reduced nasal liquid pH; A small pilot study

(2014) Mahmoud H. Abou Alaiwa et al.   Journal of Cystic Fibrosis

The Mucoid Switch in Pseudomonas aeruginosa Represses Quorum Sensing Systems and Leads to Complex Changes to Stationary Phase Virulence Factor Regulation

(2014) Ben Ryall et al.   PLoS One

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

(2014) Mahmoud H. Abou Alaiwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viability ofPseudomonas aeruginosain cough aerosols generated by persons with cystic fibrosis

(2014) Luke D Knibbs et al.   THORAX

Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity

(2014) Erwan Pernet et al.   Nature Communications

The problems of antibiotic resistance in cystic fibrosis and solutions

(2014) Carla López-Causapé et al.   Expert Review of Respiratory Medicine

Bacterial sinusitis can be a focus for initial lung colonisation and chronic lung infection in patients with cystic fibrosis

(2013) Kasper Aanæs   Journal of Cystic Fibrosis

The Anti-Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropenic Mice and Has Additive Effects with Meropenem

(2013) Thomas Secher et al.   PLoS One

Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications

(2013) Malena Cohen-Cymberknoh et al.   THORAX

Hydrogen cyanide concentrations in the breath of adult cystic fibrosis patients with and withoutPseudomonas aeruginosainfection

(2013) Francis J Gilchrist et al.   Journal of Breath Research

Cephalosporin-3′-diazeniumdiolates: Targeted NO-Donor Prodrugs for Dispersing Bacterial Biofilms

(2012) Nicolas Barraud et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

Molecular Epidemiology of Chronic Pseudomonas aeruginosa Airway Infections in Cystic Fibrosis

(2012) Nina Cramer et al.   PLoS One

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections

(2012) Balázs Rada et al.   TRENDS IN MICROBIOLOGY

The Pseudomonas aeruginosa sensor RetS switches Type III and Type VI secretion via c-di-GMP signalling

(2011) Joana A. Moscoso et al.   ENVIRONMENTAL MICROBIOLOGY

Effect of pulmonary exacerbations on long-term lung function decline in cystic fibrosis

(2011) Valerie Waters et al.   EUROPEAN RESPIRATORY JOURNAL

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

(2011) Susse Kirkelund Hansen et al.   ISME Journal

Effect of Bronchoalveolar Lavage–Directed Therapy on Pseudomonas aeruginosa Infection and Structural Lung Injury in Children With Cystic Fibrosis

(2011) Claire E. Wainwright et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chronic Stenotrophomonas maltophilia infection and exacerbation outcomes in cystic fibrosis

(2011) Valerie Waters et al.   Journal of Cystic Fibrosis

Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation

(2011) J.G. Mainz et al.   Journal of Cystic Fibrosis

Neutrophil Extracellular Trap (NET)-Mediated Killing of Pseudomonas aeruginosa: Evidence of Acquired Resistance within the CF Airway, Independent of CFTR

(2011) Robert L. Young et al.   PLoS One

Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells

(2011) S. S. Chattoraj et al.   THORAX

Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis

(2011) K. de Boer et al.   THORAX

Pseudomonas Aeruginosa: Resistance to the Max

(2011) Keith Poole   Frontiers in Microbiology

Protein Secretion Systems in Pseudomonas aeruginosa: An Essay on Diversity, Evolution, and Function

(2011) Alain Filloux   Frontiers in Microbiology

Failure to Recover to Baseline Pulmonary Function after Cystic Fibrosis Pulmonary Exacerbation

(2010) Don B. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

β-Lactamases identified in clinical isolates ofPseudomonas aeruginosa

(2010) Wei-Hua Zhao et al.   CRITICAL REVIEWS IN MICROBIOLOGY

How Pseudomonas aeruginosa adapts to various environments: a metabolomic approach

(2010) Eliane Frimmersdorf et al.   ENVIRONMENTAL MICROBIOLOGY

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons

(2010) Sophie Bleves et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Infection With Transmissible Strains of Pseudomonas aeruginosa and Clinical Outcomes in Adults With Cystic Fibrosis

(2010) Shawn D. Aaron et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bacteriophages Can Treat and PreventPseudomonas aeruginosaLung Infections

(2010) Laurent Debarbieux et al.   JOURNAL OF INFECTIOUS DISEASES

Quorum Sensing and Virulence of Pseudomonas aeruginosa during Lung Infection of Cystic Fibrosis Patients

(2010) Thomas Bjarnsholt et al.   PLoS One

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

(2010) D. A. Stoltz et al.   Science Translational Medicine

Value of serology in predicting Pseudomonas aeruginosa infection in young children with cystic fibrosis

(2010) T. A. Douglas et al.   THORAX

Controlled trial of cycled antibiotic prophylaxis to prevent initial Pseudomonas aeruginosa infection in children with cystic fibrosis

(2010) G. A. Tramper-Stranders et al.   THORAX

Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Pseudomonas aeruginosa

(2009) J.-M. Rodriguez-Martinez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

(2009) Paul Williams et al.   CURRENT OPINION IN MICROBIOLOGY

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: the ELITE trial

(2009) F. Ratjen et al.   THORAX

Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis

(2009) J G Mainz et al.   THORAX

Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression

(2008) Lucas R. Hoffman et al.   Journal of Cystic Fibrosis