A porcine model of osteosarcoma

Functional analysis and transcriptional output of the Göttingen minipig genome

(2015) Tobias Heckel et al.   BMC GENOMICS

A Genetic Porcine Model of Cancer

(2015) Lawrence B. Schook et al.   PLoS One

Viable pigs with a conditionally-activated oncogenic KRAS mutation

(2015) Shun Li et al.   TRANSGENIC RESEARCH

Non-CpG hypermethylation in placenta of mutation-induced intrauterine growth restricted bovine foetuses

(2014) Heli Venhoranta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cdc20 and securin overexpression predict short-term breast cancer survival

(2014) H Karra et al.   BRITISH JOURNAL OF CANCER

Development and translational imaging of a TP53 porcine tumorigenesis model

(2014) Jessica C. Sieren et al.   JOURNAL OF CLINICAL INVESTIGATION

Animal Models in Osteosarcoma

(2014) Maria V. Guijarro et al.   Frontiers in Oncology

Genetically modified pigs to model human diseases

(2013) Tatiana Flisikowska et al.   JOURNAL OF APPLIED GENETICS

A Porcine Model of Familial Adenomatous Polyposis

(2012) Tatiana Flisikowska et al.   GASTROENTEROLOGY

Inactivation and Inducible Oncogenic Mutation of p53 in Gene Targeted Pigs

(2012) Simon Leuchs et al.   PLoS One

Homozygous and Heterozygous p53 Knockout Rats Develop Metastasizing Sarcomas with High Frequency

(2011) Ruben van Boxtel et al.   AMERICAN JOURNAL OF PATHOLOGY

Sarcomas in TP53 germline mutation carriers

(2011) Simona Ognjanovic et al.   CANCER

The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell–matrix adhesion

(2011) Melanie Martini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Concise Review: Mesenchymal Tumors: When Stem Cells Go Mad

(2011) Alexander B. Mohseny et al.   STEM CELLS

Deficiency in p53 but not Retinoblastoma Induces the Transformation of Mesenchymal Stem Cells In vitro and Initiates Leiomyosarcoma In vivo

(2010) R. Rubio et al.   CANCER RESEARCH

Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells

(2010) I Kogan-Sakin et al.   CELL DEATH AND DIFFERENTIATION

Glucose Intolerance and Reduced Proliferation of Pancreatic  -Cells in Transgenic Pigs With Impaired Glucose-Dependent Insulinotropic Polypeptide Function

(2010) S. Renner et al.   DIABETES

RNA Interference in Pigs: Comparison of RNAi Test Systems and Expression Vectors

(2010) Claudia Merkl et al.   MOLECULAR BIOTECHNOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer

(2010) Yonglun Luo et al.   TRANSGENIC RESEARCH

Osteosarcoma incidence and survival rates from 1973 to 2004

(2009) Lisa Mirabello et al.   CANCER

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

(2009) C. V. Rao et al.   CARCINOGENESIS

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT

(2009) K Lafferty-Whyte et al.   ONCOGENE

p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway

(2008) N.V. Khromova et al.   CANCER LETTERS

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE