Functional analysis and transcriptional output of the Göttingen minipig genome

Evolution of Tibetan wild boars

(2015) Laurent A F Frantz et al.   NATURE GENETICS

IGF-1 Gene Expression Is Differentially Regulated by Estrogen Receptors α and β in Mouse Endometrial Stromal Cells and Ovarian Granulosa Cells

(2014) Yuki OGO et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

(2014) Linyan Meng et al.   NATURE

Balancing the welfare: the use of non-human primates in research

(2014) Qi Zhou   TRENDS IN GENETICS

Critical evaluation of the use of dogs in biomedical research and testing in Europe

(2014) Nina Hasiwa   ALTEX-Alternatives to Animal Experimentation

Ontogeny of CYP3A and P-Glycoprotein in the Liver and the Small Intestine of the Göttingen Minipig: An Immunohistochemical Evaluation

(2013) Els Van Peer et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Genome Sequencing Reveals Loci under Artificial Selection that Underlie Disease Phenotypes in the Laboratory Rat

(2013) Santosh S. Atanur et al.   CELL

Silencing of HEPN1 is Responsible for the Aggressive Biological Behavior of Pituitary Somatotroph Adenomas

(2013) Hu Peng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Genetically modified pigs to model human diseases

(2013) Tatiana Flisikowska et al.   JOURNAL OF APPLIED GENETICS

Affinity maturation and fine functional mapping of an antibody fragment against a novel neutralizing epitope on human vascular endothelial growth factor

(2013) Humberto Lamdan et al.   Molecular BioSystems

Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars

(2013) Mingzhou Li et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development

(2013) Jessica J. Vamathevan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

(2013) Nicole A Rapicavoli et al.   eLife

Animal models of toxicology testing: the role of pigs

(2012) Kristi L Helke et al.   Expert Opinion on Drug Metabolism & Toxicology

So many doggone traits: mapping genetics of multiple phenotypes in the domestic dog

(2012) M. Rimbault et al.   HUMAN MOLECULAR GENETICS

Site-specific targeting of antibody activity in vivo mediated by disease-associated proteases

(2012) Oran Erster et al.   JOURNAL OF CONTROLLED RELEASE

Analyses of pig genomes provide insight into porcine demography and evolution

(2012) Martien A. M. Groenen et al.   NATURE

Juvenile Toxicity: Are We Asking the Right Questions?

(2012) Noel Downes   TOXICOLOGIC PATHOLOGY

Mutant GlialCAM Causes Megalencephalic Leukoencephalopathy with Subcortical Cysts, Benign Familial Macrocephaly, and Macrocephaly with Retardation and Autism

(2011) Tania López-Hernández et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectrometry

(2011) B. Achour et al.   DRUG METABOLISM AND DISPOSITION

Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment

(2011) M. Ebeling et al.   GENOME RESEARCH

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

Lessons Learned from Alternative Methods and their Validation for a New Toxicology in the 21st Century

(2010) Thomas Hartung   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

A global map of human gene expression

(2010) Margus Lukk et al.   NATURE BIOTECHNOLOGY

New Genes in Drosophila Quickly Become Essential

(2010) S. Chen et al.   SCIENCE

The roles of cell adhesion molecules in tumor suppression and cell migration

(2010) Mei Chung Moh et al.   Cell Adhesion & Migration

The RETHINK project

(2010) Roy Forster et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Ethical implications of using the minipig in regulatory toxicology studies

(2010) John Webster et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Genetic management of the Göttingen Minipig population

(2010) Henner Simianer et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

The utility of the minipig as an animal model in regulatory toxicology

(2010) Gerd Bode et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes

(2009) Agnes Bénardeau et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Role of selection and inbreeding on the incidence of cutaneous malignant melanoma in Sinclair swine

(2009) L. Gomez-Raya et al.   JOURNAL OF ANIMAL BREEDING AND GENETICS

Global discovery of primate-specific genes in the human genome

(2009) S.-K. Tay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Rank-invariant Set Normalization (GRSN) to reduce systematic distortions in microarray data

(2008) Carl R Pelz et al.   BMC BIOINFORMATICS

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

(2008) Giorgia Egidy et al.   Molecular Cancer

Aromatase expression in the ovary: Hormonal and molecular regulation

(2008) Carlos Stocco   STEROIDS