Article
Endocrinology & Metabolism
Ivona Loncar, Sam P. J. van Dijk, Madelon J. H. Metman, Jia Feng Lin, Schelto Kruijff, Robin P. Peeters, Anton F. Engelsman, Tessa M. van Ginhoven
Summary: Based on data from the Netherlands between 2005 and 2015, the study found that restrictive diagnostic workup of thyroid nodules leads to limited candidates for active surveillance (AS) and a higher incidence of lymph node metastases.
Article
Endocrinology & Metabolism
Iwao Sugitani
Summary: The incidence of thyroid carcinoma has been increasing rapidly worldwide, mainly due to the incidental detection of small papillary thyroid carcinomas through high-resolution imaging techniques. However, the mortality rates of thyroid carcinoma have not changed, suggesting overdiagnosis and overtreatment. Active surveillance has been introduced as an alternative to immediate surgery, with strict eligibility criteria and close monitoring for cancer progression. Adequate shared decision-making is crucial, and surgery is recommended for clinically apparent metastasis or invasion.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Review
Oncology
Wen Liu, Xuejing Yan, Ruochuan Cheng
Summary: Low risk papillary thyroid microcarcinoma (PTMC) has become a clinical and social issue due to exponential increases in incidences, leading to the increasing popularity of an active surveillance (AS) approach worldwide. However, Chinese thyroid surgeons lag behind in knowledge of AS practices, and a management approach based on the Chinese population should be developed to reduce disease progression risk. It is important for surgeons to understand patient willingness, impact on the medical billing system, and doctor enthusiasm for AS implementation in China.
CANCER BIOLOGY & MEDICINE
(2022)
Article
Surgery
Mohanad R. Youssef, Abdallah S. Attia, Mahmoud Omar, Mohamed Aboueisha, Meredith N. Freeman, Mohamed Shama, Emad Kandil
Summary: In middle-aged patients with low-risk papillary thyroid cancer, lobectomy is a cost-effective strategy while active surveillance becomes cost-effective starting at the age of 69. Understanding these nuances can help personalize long-term management for patients.
Article
Endocrinology & Metabolism
Eun Kyung Lee, Jae Hoon Moon, Yul Hwangbo, Chang Hwan Ryu, Sun Wook Cho, June Young Choi, Eun-Jae Chung, Woo-Jin Jeong, Yuh-Seog Jung, Junsun Ryu, Su-jin Kim, Min Joo Kim, Yeo Koon Kim, Chang Yoon Lee, Ji Ye Lee, Hyeong Won Yu, Jeong Hun Hah, Kyu Eun Lee, You Jin Lee, Sue K. Park, Do Joon Park, Ji-hoon Kim, Young Joo Park
Summary: This multicenter prospective cohort study conducted in Korea suggests that the risk of progression during active surveillance (AS) for low-risk papillary thyroid microcarcinoma (PTMC) is low in the Korean population, but slightly higher than in other populations. Younger age, male sex, and larger tumor size were identified as independent significant factors for disease progression during AS.
Review
Endocrinology & Metabolism
Rosie Sutherland, Venessa Tsang, Roderick J. Clifton-Bligh, Matti L. Gild
Summary: The incidence of papillary thyroid carcinoma is increasing, with a focus on overdiagnosis and disease progression. While most cases follow a chronic disease course, some show more aggressive features. Current guidelines recommend against routine biopsy for nodules <= 10 mm, and active surveillance is recommended for low-risk PTMC.
CLINICAL ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Benjamin R. Roman, Juan P. Brito, Megan C. Saucke, Shivangi Lohia, Catherine B. Jensen, Nick Zaborek, Jamia Linn Jennings, Robert M. Tuttle, Louise Davies, Susan C. Pitt
Summary: Physicians treating low-risk papillary thyroid cancer generally support the active surveillance approach, but are reluctant to offer it to patients due to the lack of robust evidence, guidelines, and protocols.
ENDOCRINE PRACTICE
(2021)
Review
Oncology
Sae Rom Chung, Jung Hwan Baek, Young Jun Choi, Jeong Hyun Lee
Summary: Thermal ablation can be a good alternative treatment option for patients with low-risk papillary thyroid microcarcinomas (PTMC). It has comparable oncologic outcomes to immediate surgery with fewer complications. Active surveillance may lead to a substantial proportion of patients opting for surgery.
CURRENT ONCOLOGY REPORTS
(2022)
Article
Endocrinology & Metabolism
Samuel M. M. Cohen, Julia E. E. Noel, Michael Baroody, Lisa A. A. Orloff
Summary: According to a retrospective chart review, preoperative ultrasound can predict regional metastases in papillary thyroid microcarcinoma to some extent. The size of the tumor, distance to the thyroid capsule or trachea, tumor contour, and presence of autoimmune thyroiditis are not correlated with regional metastasis. Nodules in the superior or midpole are associated with central or lateral neck metastases, while nodules in the isthmus or inferior pole are only associated with central neck metastases. Therefore, active surveillance can be considered for patients with papillary thyroid microcarcinoma adjacent to the thyroid capsule.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Yul Hwangbo, June Young Choi, Eun Kyung Lee, Chang Hwan Ryu, Sun Wook Cho, Eun-Jae Chung, Jeong Hun Hah, Woo-Jin Jeong, Sue K. Park, Yuh-Seog Jung, Ji-Hoon Kim, Min Joo Kim, Su-Jin Kim, Yeo Koon Kim, Chang Yoon Lee, Ji Ye Lee, You Jin Lee, Hyeong Won Yu, Do Joon Park, Junsun Ryu, Young Joo Park, Kyu Eun Lee, Jae Hoon Moon
Summary: The study identified factors associated with the choice of active surveillance (AS) for patients with low-risk papillary thyroid microcarcinoma (PTMC) including patient age, tumor size, consultation with an endocrinologist, and use of a decision aid. Patients in the AS group were more influenced by information from the media, while those in the immediate surgery (iOP) group were more influenced by family members.
Article
Endocrinology & Metabolism
Akira Miyauchi, Yasuhiro Ito, Makoto Fujishima, Akihiro Miya, Naoyoshi Onoda, Minoru Kihara, Takuya Higashiyama, Hiroo Masuoka, Shiori Kawano, Takahiro Sasaki, Mitsushige Nishikawa, Shuji Fukata, Takashi Akamizu, Mitsuru Ito, Eijun Nishihara, Mako Hisakado, Kazuyoshi Kosaka, Mitsuyoshi Hirokawa, Toshitetsu Hayashi
Summary: This study compared long-term oncological outcomes of adult patients with low-risk PTMC who underwent AS or IS and found no significant clinical difference between the two groups. Therefore, AS is a viable initial management option for patients with low-risk PTMC.
Review
Oncology
Giuseppina Orlando, Gregorio Scerrino, Alessandro Corigliano, Irene Vitale, Roberta Tutino, Stefano Radellini, Francesco Cupido, Giuseppa Graceffa, Gianfranco Cocorullo, Giuseppe Salamone, Giuseppina Melfa
Summary: This review examines the most recent findings on active surveillance (AS) for papillary thyroid microcarcinoma published from 2017 to 2020. The study includes nine articles and finds that tumor volume increased by 2.7% to 23.2%, lymph node metastases occurred in 1.3% to 29% of cases, and quality of life was improved in the articles that addressed this topic. However, the evidence is considered low due to the retrospective and uncontrolled nature of most of the studies.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
Susan C. Pitt, Nan Yang, Megan C. Saucke, Nicholas Marka, Bret Hanlon, Kristin L. Long, Alexandria D. McDow, J. P. Brito, Benjamin R. Roman
Summary: The study aimed to understand factors associated with the adoption of active surveillance (AS) for thyroid cancer. Results showed that nonadopters were less likely to work in academic settings, see a high number of thyroid cancer patients, be aware of AS, use applicable guidelines, have resources or motivation for AS, while adopters were more likely to have awareness, resources, and motivation for AS.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Li Zhang, Peisong Wang, Kaixuan Li, Shuai Xue
Summary: In this study, we developed and validated a prognostic model for predicting high-risk PTMC, which could be useful for patient counseling and decision-making.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Takahiro Sasaki, Akira Miyauchi, Makoto Fujishima, Yasuhiro Ito, Takumi Kudo, Takuya Noda, Tsutomu Sano, Taketoshi Kishi, Tomohiko Nakamura
Summary: This study compared the occurrence of unfavorable events after immediate surgery (IS) and conversion surgery (CS) for low-risk papillary thyroid microcarcinoma (PTMC). The results showed that active surveillance (AS) had a significantly lower incidence of unfavorable events compared to IS. The prognoses of patients in both the AS and IS groups were excellent.
Article
Chemistry, Physical
Yan Guo, Jianjun Yang, Kuanbiao Li
Letter
Surgery
Zeming Liu, Tao Huang
WORLD JOURNAL OF SURGERY
(2016)
Article
Cell Biology
Pan Yu, Yawen Guo, Maimaiti Yusufu, Zeming Liu, Shan Wang, Xingjie Yin, Gongling Peng, Longqiang Wang, Xiangwang Zhao, Hui Guo, Tao Huang, Chunping Liu
CELL BIOLOGY INTERNATIONAL
(2016)
Article
Multidisciplinary Sciences
Yawen Guo, Pan Yu, Zeming Liu, Yusufu Maimaiti, Shan Wang, Xingjie Yin, Chunping Liu, Tao Huang
Article
Oncology
Chunping Liu, Tianwen Chen, Zeming Liu
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
Yusufu Maimaiti, Zeming Liu, Jie Tan, Kelimu Abudureyimu, Bangxing Huang, Chunping Liu, Yawen Guo, Changwen Wang, Xiu Nie, Jing Zhou, Tao Huang
ONCOTARGETS AND THERAPY
(2016)
Article
Oncology
Zeming Liu, Wen Zeng, Tianwen Chen, Yawen Guo, Chao Zhang, Chunping Liu, Tao Huang
Article
Multidisciplinary Sciences
Chunping Liu, Zeming Liu, Tianwen Chen, Wen Zeng, Yawen Guo, Tao Huang
SCIENTIFIC REPORTS
(2016)
Review
Multidisciplinary Sciences
Yawen Guo, Pan Yu, Zeming Liu, Yusufu Maimaiti, Chen Chen, Yunke Zhang, Xingjie Yin, Shan Wang, Chunping Liu, Tao Huang
Article
Oncology
Zeming Liu, Wen Zeng, Chunping Liu, Shuntao Wang, Yiquan Xiong, Yawen Guo, Xiaoyu Li, Shiran Sun, Tianwen Chen, Yusufu Maimaiti, Pan Yu, Tao Huang
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2017)
Article
Medicine, Research & Experimental
Zeming Li, Shuntao Wang, Tianwen Chen, Wen Zeng, Chunping Liu, Tao Huang
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2017)
Article
Medicine, Research & Experimental
Yawen Guo, Yusufu Maimaiti, Pan Yu, Zeming Liu, Chen Chen, Yunke Zhang, Xingjie Yin, Shan Wang, Nie Xiu, Huang Bangxing, Chunping Liu, Tao Huang
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2017)
Article
Medicine, Research & Experimental
Kelimu Abudureyimu, Yawen Guo, Yusufu Maimaiti, Zeming Liu, Jie Tan, Chunping Liu, Xiu Nie, Bangxing Huang, Jing Zhou, Tao Huang
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2017)
Article
Medicine, Research & Experimental
Tianwen Chen, Zeming Liu, Wen Zeng, Shengrong Sun
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2016)
