Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation

Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis

(2017) Yvette Simon et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity

(2015) Kavya Anjani et al.   JOURNAL OF HEPATOLOGY

Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells

(2015) Ksenia Astanina et al.   Scientific Reports

TheIGF2mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis

(2014) Stephan Laggai et al.   JOURNAL OF LIPID RESEARCH

Insulin-Like Growth Factor-I and -II Levels Are Associated with the Progression of Nonalcoholic Fatty Liver Disease in Obese Children

(2014) Stefano Cianfarani et al.   JOURNAL OF PEDIATRICS

Determining differentially expressed miRNAs and validating miRNA—target relationships using the SPRET/Ei mouse strain

(2014) S. Timmermans et al.   MAMMALIAN GENOME

HCC Development Is Associated to Peripheral Insulin Resistance in a Mouse Model of NASH

(2014) Samuele De Minicis et al.   PLoS One

Pathological changes in the biochemical profile of the liver in atherosclerosis and diabetes assessed by Raman spectroscopy

(2013) Kamila Kochan et al.   ANALYST

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by theTsc22d3gene on the X chromosome

(2013) Iris Pinheiro et al.   EMBO Molecular Medicine

The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?

(2013) Yvette Simon et al.   GUT

Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

(2013) Kengo Tomita et al.   HEPATOLOGY

IGF2Methylation Is Associated with Lipid Profile in Obese Children

(2013) Annalisa Deodati et al.   Hormone Research in Paediatrics

Metabolic Profiles of Brain Metastases

(2013) Torill Sjøbakk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Perilipin discerns chronic from acute hepatocellular steatosis

(2013) Lena Maria Pawella et al.   JOURNAL OF HEPATOLOGY

Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis

(2013) George N. Ioannou et al.   JOURNAL OF LIPID RESEARCH

Systemic TNFα Gene Therapy Synergizes With Liposomal Doxorubicine in the Treatment of Metastatic Cancer

(2013) Baowei Su et al.   MOLECULAR THERAPY

Review article: is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions?

(2012) Y. Yilmaz   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling

(2012) Sonja M. Kessler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model

(2012) Hitoshi Nishizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

(2012) Hae-Ki Min et al.   Cell Metabolism

Potential for statins in the chemoprevention and management of hepatocellular carcinoma

(2012) Amedeo Lonardo et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis

(2011) Derrick M. Van Rooyen et al.   GASTROENTEROLOGY

Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations

(2011) Terese Magnusson et al.   JOURNAL OF GENE MEDICINE

Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis

(2011) Julia Monsénégo et al.   JOURNAL OF HEPATOLOGY

Variation in the IGF2 gene promoter region is associated with intramuscular fat content in porcine skeletal muscle

(2011) Ozlem Aslan et al.   MOLECULAR BIOLOGY REPORTS

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Intracellular Gene Transfer in Rats by Tail Vein Injection of Plasmid DNA

(2010) Tian Zhou et al.   AAPS Journal

Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype

(2010) Elisabeth Tybl et al.   JOURNAL OF HEPATOLOGY

Rapid Quantitative Analysis of Lipids Using a Colorimetric Method in a Microplate Format

(2010) Yu-Shen Cheng et al.   LIPIDS

IGF2 Gene Variants and Risk of Hypertension in Obese Children and Adolescents

(2010) Maria F Faienza et al.   PEDIATRIC RESEARCH

Association between hepatic steatosis and serum IGF1 and IGFBP-3 levels in a population-based sample

(2009) Henry Völzke et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent

(2009) Walee Chamulitrat et al.   HEPATOLOGY

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

(2009) Francisco Caballero et al.   JOURNAL OF HEPATOLOGY

Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal

(2009) Naim Alkhouri et al.   Expert Review of Gastroenterology & Hepatology

Cholesterol homeostasis in T cells. Methyl-β-cyclodextrin treatment results in equal loss of cholesterol from Triton X-100 soluble and insoluble fractions

(2008) Saleemulla Mahammad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

IGF2-driven PI3 kinase and TGFβ signaling pathways in chondrogenesis

(2008) K HAMAMURA et al.   CELL BIOLOGY INTERNATIONAL

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuated Activation of Macrophage TLR9 by DNA from Virulent Mycobacteria

(2008) Alexandra K. Kiemer et al.   Journal of Innate Immunity

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

(2008) G MUSSO et al.   PROGRESS IN LIPID RESEARCH

Liver insulin-like growth factor 2 methylation in hepatitis C virus cirrhosis and further occurrence of hepatocellular carcinoma

(2008) Philippe Couvert et al.   WORLD JOURNAL OF GASTROENTEROLOGY

COPI Complex Is a Regulator of Lipid Homeostasis

(2008) Mathias Beller et al.   PLOS BIOLOGY

PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism

(2007) Manlio Vinciguerra et al.   GASTROENTEROLOGY

IGF-1 Induces SREBP-1 Expression and Lipogenesis in SEB-1 Sebocytes via Activation of the Phosphoinositide 3-Kinase/Akt Pathway

(2007) Terry M. Smith et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY