A Pharmacogenetic ‘Restriction-of-Function’ Approach Reveals Evidence for Anxiolytic-Like Actions Mediated by α5-Containing GABAA Receptors in Mice

Modulation of anxiety and fear via distinct intrahippocampal circuits

(2016) Elif Engin et al.   eLife

GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric modulator NS16085

(2015) A. Garcia de Lucas et al.   BIOCHEMICAL PHARMACOLOGY

EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABAAα2/3-positive allosteric modulators at nonsedating anxiolytic doses

(2015) Edward P. Christian et al.   JOURNAL OF NEUROPHYSIOLOGY

Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABA A Receptors Reduces Memory Interference

(2015) Elif Engin et al.   JOURNAL OF NEUROSCIENCE

Regulating anxiety with extrasynaptic inhibition

(2015) Paolo Botta et al.   NATURE NEUROSCIENCE

Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype

(2015) William T. Ralvenius et al.   Nature Communications

Neural Basis of Benzodiazepine Reward: Requirement for α2 Containing GABAA Receptors in the Nucleus Accumbens

(2014) Elif Engin et al.   NEUROPSYCHOPHARMACOLOGY

Structure, Function, and Modulation of GABAAReceptors

(2012) Erwin Sigel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice

(2012) Kiersten S. Smith et al.   NEUROPHARMACOLOGY

Differential Roles of GABAA Receptor Subtypes in Benzodiazepine-Induced Enhancement of Brain-Stimulation Reward

(2012) Lauren M Reynolds et al.   NEUROPSYCHOPHARMACOLOGY

Dissecting the role of diazepam-sensitive γ-aminobutyric acid type A receptors in defensive behavioral reactivity to mild threat

(2012) Christina Koester et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

(2011) Uwe Rudolph et al.   NATURE REVIEWS DRUG DISCOVERY

Antidepressant-like properties of α2-containing GABAA receptors

(2010) Isabel Vollenweider et al.   BEHAVIOURAL BRAIN RESEARCH

Neural bases for addictive properties of benzodiazepines

(2010) Kelly R. Tan et al.   NATURE

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON