Oral Administration of Sitagliptin Activates CREB and Is Neuroprotective in Murine Model of Brain Trauma

Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats

(2016) Yu-Wen Yu et al.   JOURNAL OF NEUROTRAUMA

Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria

(2016) Brian DellaValle et al.   MALARIA JOURNAL

Long-acting glucagon-like peptide-1 receptor agonists have direct access to and effects on pro-opiomelanocortin/cocaine- and amphetamine-stimulated transcript neurons in the mouse hypothalamus

(2016) Lotte Bjerre Knudsen et al.   Journal of Diabetes Investigation

In Alzheimer’s Disease, 6-Month Treatment with GLP-1 Analog Prevents Decline of Brain Glucose Metabolism: Randomized, Placebo-Controlled, Double-Blind Clinical Trial

(2016) Michael Gejl et al.   Frontiers in Aging Neuroscience

An interaction between glucagon-like peptide-1 and adenosine contributes to cardioprotection of a dipeptidyl peptidase 4 inhibitor from myocardial ischemia-reperfusion injury

(2015) Madoka Ihara et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

(2015) MingJie Ma et al.   Cardiovascular Diabetology

The Neuroprotective Effect of Liraglutide is Mediated by Glucagon-Like Peptide 1 Receptor-Mediated Activation of cAMP/PKA/CREB Pathway

(2015) Yi Bao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline

(2015) V. A. Gault et al.   DIABETES OBESITY & METABOLISM

Sitagliptin attenuated brain damage and cognitive impairment in mice with chronic cerebral hypo-perfusion through suppressing oxidative stress and inflammatory reaction

(2015) Tzu-Hsien Tsai et al.   JOURNAL OF HYPERTENSION

Sitagliptin attenuates transient cerebral ischemia/reperfusion injury in diabetic rats: Implication of the oxidative–inflammatory–apoptotic pathway

(2015) Ayman E. El-Sahar et al.   LIFE SCIENCES

Preservation of the Blood Brain Barrier and Cortical Neuronal Tissue by Liraglutide, a Long Acting Glucagon-Like-1 Analogue, after Experimental Traumatic Brain Injury

(2015) Jakob Hakon et al.   PLoS One

GLP-1 improves neuropathology after murine cold lesion brain trauma

(2015) Brian DellaValle et al.   Annals of Clinical and Translational Neurology

At the Centennial of Michaelis and Menten, Competing Michaelis-Menten Steps Explain Effect of GLP-1 on Blood-Brain Transfer and Metabolism of Glucose

(2014) Michael Gejl et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Alogliptin, a dipeptidylpeptidase-4 inhibitor, for patients with diabetes mellitus type 2, induces tolerance to focal cerebral ischemia in non-diabetic, normal mice

(2013) Dong Yang et al.   BRAIN RESEARCH

DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

(2013) Hiranya Pintana et al.   JOURNAL OF ENDOCRINOLOGY

Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress

(2013) Mohit K. Sharma et al.   JOURNAL OF NEUROCHEMISTRY

Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers

(2013) Steven T. DeKosky et al.   Nature Reviews Neurology

Dipeptidyl Peptidase IV Inhibition Activates CREB and Improves Islet Vascularization through VEGF-A/VEGFR-2 Signaling Pathway

(2013) Balaji Samikannu et al.   PLoS One

Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice

(2012) Lital Rachmany et al.   AGE

DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

(2012) Noppamas Pipatpiboon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glucagon-Like Peptide-1 Decreases Intracerebral Glucose Content by Activating Hexokinase and Changing Glucose Clearance during Hyperglycemia

(2012) Michael Gejl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

17β-Oestradiol Anti-Inflammatory Effects in Primary Astrocytes Require Oestrogen Receptor β-Mediated Neuroglobin Up-Regulation

(2012) E. De Marinis et al.   JOURNAL OF NEUROENDOCRINOLOGY

Early management of severe traumatic brain injury

(2012) Jeffrey V Rosenfeld et al.   LANCET

The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA

(2010) Yumei Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In vivo expression of neuroglobin in reactive astrocytes during neuropathology in murine models of traumatic brain injury, cerebral malaria, and autoimmune encephalitis

(2010) Brian DellaValle et al.   GLIA

The natural history of brain contusion: an analysis of radiological and clinical progression

(2009) Hussein Alahmadi et al.   JOURNAL OF NEUROSURGERY

Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway

(2009) R. Kimura et al.   NEUROSCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Glucagon-like peptide-1, glucose homeostasis and diabetes

(2008) Jens J. Holst et al.   TRENDS IN MOLECULAR MEDICINE