Wedelolactone Enhances Osteoblastogenesis but Inhibits Osteoclastogenesis through Sema3A/NRP1/PlexinA1 Pathway

Wedelolactone inhibits breast cancer-induced osteoclastogenesis by decreasing Akt/mTOR signaling

(2014) CHIA-JUNG HSIEH et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Inhibitory effect of Ecliptae herba extract and its component wedelolactone on pre-osteoclastic proliferation and differentiation

(2014) Yan-Qiu Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Semaphorins and plexins as therapeutic targets

(2014) Thomas Worzfeld et al.   NATURE REVIEWS DRUG DISCOVERY

Sema3A regulates bone-mass accrual through sensory innervations

(2013) Toru Fukuda et al.   NATURE

Class 3 semaphorins as a therapeutic target

(2012) Yoshio Goshima et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

(2012) SIVALOKANATHAN SARVESWARAN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Therapeutic effect of aqueous extract from Ecliptae herba on bone metabolism of ovariectomized rats

(2012) Zhi-Guo Zhang et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Osteoprotection by semaphorin 3A

(2012) Mikihito Hayashi et al.   NATURE

PLCγ2: where bone and immune cells find their common ground

(2010) Roberta Faccio et al.   Annals of the New York Academy of Sciences

Total flavonoids of Herba Epimedii improves osteogenesis and inhibits osteoclastogenesis of human mesenchymal stem cells

(2009) Jin-Fang Zhang et al.   PHYTOMEDICINE

Phospholipase C 2 Modulates Integrin Signaling in the Osteoclast by Affecting the Localization and Activation of Src Kinase

(2008) H. Epple et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

(2008) L. Pederson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA