Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis

Protective effect of curcumin on TNBS-induced intestinal inflammation is mediated through the JAK/STAT pathway

(2016) Xingxing Zhang et al.   BMC Complementary and Alternative Medicine

Interferon-γ stimulates human follicular dendritic cell-like cells to produce prostaglandins via the JAK-STAT pathway

(2015) Jini Kim et al.   MOLECULAR IMMUNOLOGY

The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

(2015) Muthu Shanmugam et al.   MOLECULES

Inhibition of JAK1, 2/STAT3 Signaling Induces Apoptosis, Cell Cycle Arrest, and Reduces Tumor Cell Invasion in Colorectal Cancer Cells

(2015) Hua Xiong et al.   NEOPLASIA

Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study

(2014) Martha L. Slattery et al.   BREAST CANCER RESEARCH AND TREATMENT

Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH)

(2014) M. Sałaga et al.   Journal of Crohns & Colitis

Curcumin and Inflammatory Bowel Disease: Potential and Limits of Innovative Treatments

(2014) Liza Vecchi Brumatti et al.   MOLECULES

The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

(2013) A. Heine et al.   BLOOD

Curcumin: A Boon to Colonic Diseases

(2013) Rashmi Sareen et al.   CURRENT DRUG TARGETS

BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice

(2013) Akihito Harusato et al.   INFLAMMATORY BOWEL DISEASES

Altered human gut dendritic cell properties in ulcerative colitis are reversed byLactobacillus plantarumextracellular encrypted peptide STp

(2013) Hafid O. Al-Hassi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

(2012) Subash C. Gupta et al.   AAPS Journal

Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors

(2012) Anna Yarilina et al.   ARTHRITIS AND RHEUMATISM

IL-17/IFN-γ Interactions Regulate Intestinal Inflammation in TNBS-Induced Acute Colitis

(2012) Yu Jin et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Krüppel-Like Factor 5 Protects against Murine Colitis and Activates JAK-STAT Signaling In Vivo

(2012) Marie-Pier Tetreault et al.   PLoS One

Aberrant plasmacytoid dendritic cell distribution and function in patients with Crohn's disease and ulcerative colitis

(2011) D. C. Baumgart et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Intercellular adhesion molecule-1 (ICAM-1) in ulcerative colitis: presence, visualization, and significance

(2010) Ben VAINER   APMIS

IFN-γ activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production

(2010) Michael Conzelmann et al.   BIOCHEMICAL PHARMACOLOGY

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

(2010) Aiping Bai et al.   BIOCHEMICAL PHARMACOLOGY

Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis

(2010) N. Schmidt et al.   GUT

OX40 is required for regulatory T cell–mediated control of colitis

(2010) Thibault Griseri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IFN-  Is a Negative Regulator of IL-23 in Murine Macrophages and Experimental Colitis

(2010) S. Z. Sheikh et al.   JOURNAL OF IMMUNOLOGY

Loss of Jak2 Selectively Suppresses DC-Mediated Innate Immune Response and Protects Mice from Lethal Dose of LPS-Induced Septic Shock

(2010) Jixin Zhong et al.   PLoS One

Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1β and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease

(2009) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

(2009) Zhipeng Wang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Directing dendritic cell immunotherapy towards successful cancer treatment

(2009) Rachel Lubong Sabado et al.   Immunotherapy

The role of dendritic cell subsets in 2,4,6-trinitrobenzene sulfonic acid-induced ileitis

(2009) Shoichi Hoshino et al.   JOURNAL OF AUTOIMMUNITY

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning

(2009) I D Iliev et al.   Mucosal Immunology

Jak3 Is Involved in Dendritic Cell Maturation and CCR7-Dependent Migration

(2009) Ana Rivas-Caicedo et al.   PLoS One

Granulocyte and Monocyte Adsorption Apheresis Therapy Modulates Monocyte-Derived Dendritic Cell Function in Patients With Ulcerative Colitis

(2009) Yuko Iwakami et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Curcumin prevents human dendritic cell response to immune stimulants

(2008) Shawna A. Shirley et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

JAK/STAT and PI3K/AKT Pathways Form a Mutual Transactivation Loop and Afford Resistance to Oxidative Stress-Induced Apoptosis in Cardiomyocytes

(2008) Yanjie Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21

(2008) Daniele Fina et al.   GASTROENTEROLOGY

Alterations in myeloid dendritic cell innate immune responses in the Gαi2-deficient mouse model of colitis

(2008) J. A. Peña et al.   INFLAMMATORY BOWEL DISEASES