Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities

Consequences of New Approach of Chemical Stability Tests of Active Pharmaceutical Ingredients (APIs)

(2016) Marzena Jamrógiewicz   Frontiers in Pharmacology

Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4acid hydrolysis

(2015) Prinesh N. Patel et al.   JOURNAL OF MASS SPECTROMETRY

Application of vibrational spectroscopy, thermal analyses and X-ray diffraction in the rapid evaluation of the stability in solid-state of ranitidine, famotidine and cimetidine

(2015) Marzena Jamrógiewicz et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

SwissTargetPrediction: a web server for target prediction of bioactive small molecules

(2014) David Gfeller et al.   NUCLEIC ACIDS RESEARCH

The Assessment of Impurities for Genotoxic Potential and Subsequent Control in Drug Substance and Drug Product

(2013) Linda K. Dow et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Practical and regulatory considerations for stability-indicating methods for the assay of bulk drugs and drug formulations

(2013) Rubén M. Maggio et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products

(2012) Saranjit Singh et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Simultaneous determination of ivabradine and N-desmethylivabradine in human plasma and urine using a LC-MS/MS method: application to a pharmacokinetic study

(2012) Chengtao Lu et al.   Acta Pharmaceutica Sinica B

The value of in silico chemistry in the safety assessment of chemicals in the consumer goods and pharmaceutical industries

(2011) Sandeep Modi et al.   DRUG DISCOVERY TODAY

Exploring HCN channels as novel drug targets

(2011) Otilia Postea et al.   NATURE REVIEWS DRUG DISCOVERY

A stability-indicating HPLC assay with diode array detection for the determination of a benzylpenicillin prodrug in aqueous solutions

(2009) Rohit Jain et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS