Expressing Constitutively Active Rheb in Adult Dorsal Root Ganglion Neurons Enhances the Integration of Sensory Axons that Regenerate Across a Chondroitinase-Treated Dorsal Root Entry Zone Following Dorsal Root Crush

Macrophage activation and its role in repair and pathology after spinal cord injury

(2015) John C. Gensel et al.   BRAIN RESEARCH

The proinflammatory cytokine, interleukin-17A, augments mitochondrial function and neurite outgrowth of cultured adult sensory neurons derived from normal and diabetic rats

(2015) Tarek Habash et al.   EXPERIMENTAL NEUROLOGY

Macrophage-T Cell Interactions Mediate Neuropathic Pain through the Glucocorticoid-induced Tumor Necrosis Factor Ligand System

(2015) Yuka Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar

(2015) D. Wu et al.   JOURNAL OF NEUROSCIENCE

Pten Deletion Promotes Regrowth of Corticospinal Tract Axons 1 Year after Spinal Cord Injury

(2015) K. Du et al.   JOURNAL OF NEUROSCIENCE

mRNAs and Protein Synthetic Machinery Localize into Regenerating Spinal Cord Axons When They Are Provided a Substrate That Supports Growth

(2015) A. L. Kalinski et al.   JOURNAL OF NEUROSCIENCE

Inhibitory Injury Signaling Represses Axon Regeneration After Dorsal Root Injury

(2015) Fernando M. Mar et al.   MOLECULAR NEUROBIOLOGY

Local Delivery of High-Dose Chondroitinase ABC in the Sub-Acute Stage Promotes Axonal Outgrowth and Functional Recovery after Complete Spinal Cord Transection

(2015) Chu-Hsun Cheng et al.   PLoS One

Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS

(2015) Jason B. Carmel et al.   Frontiers in Molecular Neuroscience

Cell intrinsic control of axon regeneration

(2014) F. M. Mar et al.   EMBO REPORTS

Cytokine pathways regulating glial and leukocyte function after spinal cord and peripheral nerve injury

(2014) Dominic Bastien et al.   EXPERIMENTAL NEUROLOGY

Blockade of excitatory synaptogenesis with proximal dendrites of dentate granule cells following rapamycin treatment in a mouse model of temporal lobe epilepsy

(2014) Ruth Yamawaki et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mammalian Target of Rapamycin's Distinct Roles and Effectiveness in Promoting Compensatory Axonal Sprouting in the Injured CNS

(2014) D.-H. Lee et al.   JOURNAL OF NEUROSCIENCE

Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL

(2014) Catarina Osório et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Functional significance of macrophage-derived exosomes in inflammation and pain

(2014) Marguerite K. McDonald et al.   PAIN

mTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injury

(2013) Lingli Liang et al.   BRAIN RESEARCH

PTEN Inhibition to Facilitate Intrinsic Regenerative Outgrowth of Adult Peripheral Axons

(2013) K. J. Christie et al.   JOURNAL OF NEUROSCIENCE

Contribution of Macrophages to Enhanced Regenerative Capacity of Dorsal Root Ganglia Sensory Neurons by Conditioning Injury

(2013) M. J. Kwon et al.   JOURNAL OF NEUROSCIENCE

The mTOR Signaling Pathway Regulates Pain-Related Synaptic Plasticity in Rat Entorhinal-Hippocampal Pathways

(2013) Dan Lyu et al.   Molecular Pain

Interleukin-6 contributes to CNS axon regeneration upon inflammatory stimulation

(2013) M Leibinger et al.   Cell Death & Disease

Interleukin-17 sensitizes joint nociceptors to mechanical stimuli and contributes to arthritic pain through neuronal interleukin-17 receptors in rodents

(2012) Frank Richter et al.   ARTHRITIS AND RHEUMATISM

Regulation of TOR by small GTPases

(2012) Raúl V Durán et al.   EMBO REPORTS

Exogenous BDNF enhances the integration of chronically injured axons that regenerate through a peripheral nerve grafted into a chondroitinase-treated spinal cord injury site

(2012) Veronica J. Tom et al.   EXPERIMENTAL NEUROLOGY

Multiple Roles for Mammalian Target of Rapamycin Signaling in Both Glutamatergic and GABAergic Synaptic Transmission

(2012) M. C. Weston et al.   JOURNAL OF NEUROSCIENCE

Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia

(2012) Gisela Segond von Banchet et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Role of mTOR in neuroprotection and axon regeneration after inflammatory stimulation

(2012) Marco Leibinger et al.   NEUROBIOLOGY OF DISEASE

microRNA-222 Targeting PTEN Promotes Neurite Outgrowth from Adult Dorsal Root Ganglion Neurons following Sciatic Nerve Transection

(2012) Songlin Zhou et al.   PLoS One

Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration

(2011) Sang Ryong Kim et al.   ANNALS OF NEUROLOGY

In Vivo Imaging of Dorsal Root Regeneration: Rapid Immobilization and Presynaptic Differentiation at the CNS/PNS Border

(2011) A. Di Maio et al.   JOURNAL OF NEUROSCIENCE

Keratan Sulfate Restricts Neural Plasticity after Spinal Cord Injury

(2011) S. Imagama et al.   JOURNAL OF NEUROSCIENCE

Pten Knockdown In Vivo Increases Excitatory Drive onto Dentate Granule Cells

(2011) B. W. Luikart et al.   JOURNAL OF NEUROSCIENCE

Targeting Adenosine Monophosphate-Activated Protein Kinase (AMPK) in Preclinical Models Reveals a Potential Mechanism for the Treatment of Neuropathic Pain

(2011) Ohannes K Melemedjian et al.   Molecular Pain

AAV Transduction of Dopamine Neurons With Constitutively Active Rheb Protects From Neurodegeneration and Mediates Axon Regrowth

(2011) Sang Ryong Kim et al.   MOLECULAR THERAPY

Expression and distribution of mTOR, p70S6K, 4E-BP1, and their phosphorylated counterparts in rat dorsal root ganglion and spinal cord dorsal horn

(2010) Ji-Tain Xu et al.   BRAIN RESEARCH

Schwann cell migration is integrin-dependent and inhibited by astrocyte-produced aggrecan

(2010) Fardad T. Afshari et al.   GLIA

Mammalian Target of Rapamycin (mTOR) Activation Increases Axonal Growth Capacity of Injured Peripheral Nerves

(2010) Namiko Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocyte-Produced Ephrins Inhibit Schwann Cell Migration via VAV2 Signaling

(2010) F. T. Afshari et al.   JOURNAL OF NEUROSCIENCE

Below Level Central Pain Induced by Discrete Dorsal Spinal Cord Injury

(2010) Julie Wieseler et al.   JOURNAL OF NEUROTRAUMA

Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons

(2010) Matthew RJ Mason et al.   MOLECULAR THERAPY

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Tsc2-Rheb signaling regulates EphA-mediated axon guidance

(2010) Duyu Nie et al.   NATURE NEUROSCIENCE

Topographically specific regeneration of sensory axons in the spinal cord

(2010) P. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble Nogo Receptor Down-regulates Expression of Neuronal Nogo-A to Enhance Axonal Regeneration

(2009) Xiangmin Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blockade of Nogo Receptor Ligands Promotes Functional Regeneration of Sensory Axons after Dorsal Root Crush

(2009) P. A. Harvey et al.   JOURNAL OF NEUROSCIENCE

Combining Peripheral Nerve Grafts and Chondroitinase Promotes Functional Axonal Regeneration in the Chronically Injured Spinal Cord

(2009) V. J. Tom et al.   JOURNAL OF NEUROSCIENCE

Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

(2008) Megan Ryan Detloff et al.   EXPERIMENTAL NEUROLOGY

Chondroitinase ABC-Mediated Plasticity of Spinal Sensory Function

(2008) W. B. J. Cafferty et al.   JOURNAL OF NEUROSCIENCE

Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury

(2008) Ruizhong Wang et al.   NATURE NEUROSCIENCE

Local Translation in Primary Afferent Fibers Regulates Nociception

(2008) Lydia Jiménez-Díaz et al.   PLoS One

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE