Icariin ameliorates IgA nephropathy by inhibition of nuclear factor kappa b/Nlrp3 pathway

Icariin protects rats against 5/6 nephrectomy-induced chronic kidney failure by increasing the number of renal stem cells

(2015) Zhongdi Huang et al.   BMC Complementary and Alternative Medicine

The Akt/mTOR/p70S6K pathway is activated in IgA nephropathy and rapamycin may represent a viable treatment option

(2015) Jihua Tian et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Anti-inflammatory effects of triptolide on IgA nephropathy in rats

(2015) Liyu He et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii

(2015) Chenrui Li et al.   LIFE SCIENCES

Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation

(2015) B. Liu et al.   NEUROSCIENCE

Protective effect of icariin on kidney in 5/6 nephrectomized rats and its mechanism

(2014) S.R. Liang et al.   GENETICS AND MOLECULAR RESEARCH

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome

(2013) Shun-Min Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Canonical and non-canonical effects of the NLRP3 inflammasome in kidney inflammation and fibrosis

(2013) Georg Lorenz et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effect of atorvastatin on IgA nephropathy in the rat

(2012) Ze’ev Katzir et al.   CLINICAL NEPHROLOGY

Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy

(2012) Beili Shi et al.   MEDIATORS OF INFLAMMATION

Pathogenesis of IgA nephropathy

(2012) Kar Neng Lai   Nature Reviews Nephrology

Protective effect of Icariin on the early stage of experimental diabetic nephropathy induced by streptozotocin via modulating transforming growth factor β1 and type IV collagen expression in rats

(2011) Min-You Qi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Regulation of adaptive immunity by the NLRP3 inflammasome

(2010) Mingkuan Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Additive effect of PPAR-γ agonist and ARB in treatment of experimental IgA nephropathy

(2010) Kar Neng Lai et al.   PEDIATRIC NEPHROLOGY

Interleukin-1 cluster gene polymorphisms in childhood IgA nephropathy

(2009) Won Ho Hahn et al.   PEDIATRIC NEPHROLOGY