Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria

Progress in the Fight Against Multidrug-Resistant Bacteria? A Review of U.S. Food and Drug Administration–Approved Antibiotics, 2010–2015

(2016) Dalia Deak et al.   ANNALS OF INTERNAL MEDICINE

Horizontal Transfer of Carbapenemase-Encoding Plasmids and Comparison with Hospital Epidemiology Data

(2016) C. A. Hardiman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Drug combination therapy increases successful drug repositioning

(2016) Wei Sun et al.   DRUG DISCOVERY TODAY

Rifabutin: where do we stand in 2016?

(2016) Yoann Crabol et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing

(2016) Kenneth P. Smith et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol

(2016) Yaakov Dickstein et al.   BMJ Open

The impact of hospital-acquired infections with multidrug-resistant bacteria in an oncology intensive care unit

(2015) P. Cornejo-Juárez et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Auranofin efficacy against MDRStreptococcus pneumoniaeandStaphylococcus aureusinfections

(2015) Leire Aguinagalde et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?

(2015) David Brown   NATURE REVIEWS DRUG DISCOVERY

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

(2015) Michael B. Harbut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection

(2015) Shanshan He et al.   Science Translational Medicine

Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library

(2015) Shiuan Chen et al.   TOXICOLOGICAL SCIENCES

Auranofin: Repurposing an Old Drug for a Golden New Age

(2015) Christine Roder et al.   Drugs in research & development

Supergenomic Network Compression and the Discovery of EXP1 as a Glutathione Transferase Inhibited by Artesunate

(2014) Andreas Martin Lisewski et al.   CELL

Combination antibiotic treatment versus monotherapy for multidrug-resistant, extensively drug-resistant, and pandrug-resistant Acinetobacter infections: a systematic review

(2014) P. Poulikakos et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

When Does 2 Plus 2 Equal 5? A Review of Antimicrobial Synergy Testing

(2014) C. D. Doern   JOURNAL OF CLINICAL MICROBIOLOGY

Chemical signatures and new drug targets for gametocytocidal drug development

(2014) Wei Sun et al.   Scientific Reports

Identification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug library

(2014) Jie Feng et al.   Emerging Microbes & Infections

Colistin and Rifampicin Compared With Colistin Alone for the Treatment of Serious Infections Due to Extensively Drug-Resistant Acinetobacter baumannii: A Multicenter, Randomized Clinical Trial

(2013) Emanuele Durante-Mangoni et al.   CLINICAL INFECTIOUS DISEASES

Rifampicin-resistant and rifabutin-susceptible Mycobacterium tuberculosis strains: a breakpoint artefact?

(2013) T. Schon et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Combination approaches to combat multidrug-resistant bacteria

(2013) Roberta J. Worthington et al.   TRENDS IN BIOTECHNOLOGY

Treatment Outcome of Bacteremia Due to KPC-Producing Klebsiella pneumoniae: Superiority of Combination Antimicrobial Regimens

(2012) Zubair A. Qureshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Repurposing screens identify rifamycins as potential broad-spectrum therapy for multidrug-resistantAcinetobacter baumanniiand select agent microorganisms

(2012) Brett A Chromy et al.   Future Microbiology

The antifungal mechanism of action of zinc pyrithione

(2011) N.L. Reeder et al.   BRITISH JOURNAL OF DERMATOLOGY

Methodological and practical challenges for personalized cancer therapies

(2011) Ignacio I. Wistuba et al.   Nature Reviews Clinical Oncology

The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics

(2011) R. Huang et al.   Science Translational Medicine

Lateral patch-clamping in a standard 1536-well microplate format

(2010) Kum Cheong Tang et al.   LAB ON A CHIP

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

(2009) Steven A. Titus et al.   ANALYTICAL BIOCHEMISTRY

Microfractionation Revisited: A 1536 Well High Resolution Screening Assay

(2009) Martin Giera et al.   ANALYTICAL CHEMISTRY

Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices

(2009) James H. Jorgensen et al.   CLINICAL INFECTIOUS DISEASES