miR-708/LSD1 axis regulates the proliferation and invasion of breast cancer cells

MicroRNA-708 is downregulated in hepatocellular carcinoma and suppresses tumor invasion and migration

(2015) Guangjun Li et al.   BIOMEDICINE & PHARMACOTHERAPY

The role of themiR-31/FIH1 pathway in TGF-β-induced liver fibrosis

(2015) Jiangfeng Hu et al.   CLINICAL SCIENCE

Metformin induces ER stress-dependent apoptosis through miR-708-5p/NNAT pathway in prostate cancer

(2015) J Yang et al.   Oncogenesis

LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition

(2015) Satoi Nagasawa et al.   PLoS One

High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients

(2014) Remco S Derr et al.   BMC CANCER

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

A miR-590/Acvr2a/Rad51b Axis Regulates DNA Damage Repair during mESC Proliferation

(2014) Qidong Liu et al.   Stem Cell Reports

Retinoic acid impairs estrogen signaling in breast cancer cells by interfering with activation of LSD1 via PKA

(2013) Maria Neve Ombra et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

miRNA Dysregulation in Breast Cancer

(2013) L. Mulrane et al.   CANCER RESEARCH

Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

(2013) Shauna N. Vasilatos et al.   CARCINOGENESIS

miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2

(2013) Tao Song et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The Deubiquitinase USP28 Stabilizes LSD1 and Confers Stem-Cell-like Traits to Breast Cancer Cells

(2013) Yadi Wu et al.   Cell Reports

The histone demethylase LSD1 is required for estrogen-dependent S100A7 gene expression in human breast cancer cells

(2012) Seung Eun Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miRNA-708 Control of CD44+ Prostate Cancer-Initiating Cells

(2012) S. Saini et al.   CANCER RESEARCH

Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers

(2012) J. S. Jang et al.   CLINICAL CANCER RESEARCH

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

(2011) Qingsong Zhu et al.   AMINO ACIDS

Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14

(2011) Q. Li et al.   CANCER RESEARCH

MicroRNA-708 Induces Apoptosis and Suppresses Tumorigenicity in Renal Cancer Cells

(2011) S. Saini et al.   CANCER RESEARCH

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer

(2009) Yan Wang et al.   CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer

(2008) Jian-Jun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin

(2008) O. Kovalchuk et al.   MOLECULAR CANCER THERAPEUTICS

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE

MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

(2008) L.-X. Yan et al.   RNA