RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner
Authors
Keywords
-
Journal
Biology Open
Volume 5, Issue 9, Pages 1283-1289
Publisher
The Company of Biologists
Online
2016-08-05
DOI
10.1242/bio.020461
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ARL3 regulates trafficking of prenylated phototransduction proteins to the rod outer segment
- (2016) Zachary C. Wright et al. HUMAN MOLECULAR GENETICS
- Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors
- (2016) Christin Hanke-Gogokhia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused byTTLL5mutations
- (2016) Xun Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PDE6δ-mediated sorting of INPP5E into the cilium is determined by cargo-carrier affinity
- (2016) Eyad Kalawy Fansa et al. Nature Communications
- The carboxyl terminal mutational hotspot of the ciliary disease protein RPGRORF15(retinitis pigmentosa GTPase regulator) is glutamylatedin vivo
- (2016) Kollu N. Rao et al. Biology Open
- PDE6D binds to the C-terminus of RPGR in a prenylation-dependent manner
- (2015) J.-J. Lee et al. EMBO REPORTS
- The N- and C-terminal ends of RPGR can bind to PDE6
- (2015) E. K. Fansa et al. EMBO REPORTS
- Mistrafficking of prenylated proteins causes retinitis pigmentosa 2
- (2015) Houbin Zhang et al. FASEB JOURNAL
- KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport
- (2014) Malte Schmick et al. CELL
- Membrane Protein Transport in Photoreceptors: The Function of PDE
- (2014) W. Baehr INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
- The interplay between RPGR, PDEδ and Arl2/3 regulate the ciliary targeting of farnesylated cargo
- (2013) Denise Wätzlich et al. EMBO REPORTS
- A HomozygousPDE6DMutation in Joubert Syndrome Impairs Targeting of Farnesylated INPP5E Protein to the Primary Cilium
- (2013) Sophie Thomas et al. HUMAN MUTATION
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting
- (2012) M. C. Humbert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons
- (2012) H Patil et al. Cell Death & Disease
- The role of RPGR in cilia formation and actin stability
- (2011) Milica Gakovic et al. HUMAN MOLECULAR GENETICS
- The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins
- (2011) Anchal Chandra et al. NATURE CELL BIOLOGY
- Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo
- (2011) Shehab A Ismail et al. Nature Chemical Biology
- RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments
- (2011) J. R. Christiansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies
- (2009) Hemant Khanna et al. NATURE GENETICS
- INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse
- (2009) Monique Jacoby et al. NATURE GENETICS
- Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies
- (2009) Stephanie L Bielas et al. NATURE GENETICS
- Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome
- (2008) Vincent Cantagrel et al. AMERICAN JOURNAL OF HUMAN GENETICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now