Calcium/Calmodulin-Dependent Kinase IV Facilitates the Recruitment of Interleukin-17-Producing Cells to Target Organs Through the CCR6/CCL20 Axis in Th17 Cell-Driven Inflammatory Diseases

Association of Variants inCCR6With Susceptibility to Lupus Nephritis in Chinese

(2015) Xu-jie Zhou et al.   Arthritis & Rheumatology

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3+regulatory T cells in MRL/lprmice

(2014) Tomohiro Koga et al.   AUTOIMMUNITY

Genetics of systemic lupus erythematosus: immune responses and end organ resistance to damage

(2014) Chao Dai et al.   CURRENT OPINION IN IMMUNOLOGY

CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance

(2014) Tomohiro Koga et al.   JOURNAL OF CLINICAL INVESTIGATION

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

IL-2 Protects Lupus-Prone Mice from Multiple End-Organ Damage by Limiting CD4−CD8−IL-17–Producing T Cells

(2014) Masayuki Mizui et al.   JOURNAL OF IMMUNOLOGY

Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers

(2014) Hélène Jeltsch-David et al.   Nature Reviews Neurology

The Pathogenesis of Lupus Nephritis

(2013) M. Lech et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues

(2013) Wen Zhang et al.   PLoS One

Interleukin-17 Cytokines Are Critical in Development of Fatal Lupus Glomerulonephritis

(2012) Prapaporn Pisitkun et al.   IMMUNITY

CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver

(2012) Ye Htun Oo et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: Protein Phosphatase 2A Confers Susceptibility to Autoimmune Disease through an IL-17-Dependent Mechanism

(2012) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Calcium/Calmodulin-Dependent Protein Kinase IV Suppresses IL-2 Production and Regulatory T Cell Activity in Lupus

(2012) T. Koga et al.   JOURNAL OF IMMUNOLOGY

Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis

(2012) Hans-Joachim Paust et al.   KIDNEY INTERNATIONAL

Taming lupus—a new understanding of pathogenesis is leading to clinical advances

(2012) Zheng Liu et al.   NATURE MEDICINE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

The IL-17 pathway as a major therapeutic target in autoimmune diseases

(2010) Yan Hu et al.   Annals of the New York Academy of Sciences

Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV

(2010) Kunihiro Ichinose et al.   ARTHRITIS AND RHEUMATISM

CCR6 Recruits Regulatory T Cells and Th17 Cells to the Kidney in Glomerulonephritis

(2010) J. E. Turner et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cytokines in Systemic Lupus Erythematosus

(2009) Elaine Lourenco et al.   CURRENT MOLECULAR MEDICINE

Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

(2009) Erin G. Harper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autoantibody-mediated neuroinflammation: Pathogenesis of neuropsychiatric systemic lupus erythematosus in the NZM88 murine model

(2008) Tapan K. Mondal et al.   BRAIN BEHAVIOR AND IMMUNITY

Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller

(2008) Luigi Racioppi et al.   TRENDS IN IMMUNOLOGY

The chemokine network in systemic lupus erythematous nephritis

(2007) Brad et al.   Frontiers in Bioscience-Landmark