Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis

Polyclonal Adaptive Regulatory CD4 Cells That Can Reverse Type I Diabetes Become Oligoclonal Long-Term Protective Memory Cells

(2014) E. Godebu et al.   JOURNAL OF IMMUNOLOGY

Hypomethylation at the Regulatory T Cell–Specific Demethylated Region in CD25hiT Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis

(2014) David Bending et al.   JOURNAL OF IMMUNOLOGY

Brief Report: Anti-Tumor Necrosis Factor α Targets Protein Kinase B/c-Akt-Induced Resistance of Effector Cells to Suppression in Juvenile Idiopathic Arthritis

(2013) Ellen J. Wehrens et al.   ARTHRITIS AND RHEUMATISM

Dysregulation of CD4+CD25highT Cells in the Synovial Fluid of Patients With Antibiotic-Refractory Lyme Arthritis

(2013) Nalini K. Vudattu et al.   ARTHRITIS AND RHEUMATISM

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

(2013) Samantha L. Bailey-Bucktrout et al.   IMMUNITY

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

(2013) Anne Hinks et al.   NATURE GENETICS

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

Using synthetic templates to design an unbiased multiplex PCR assay

(2013) Christopher S. Carlson et al.   Nature Communications

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

(2012) T. Duhen et al.   BLOOD

Requirement for Diverse TCR Specificities Determines Regulatory T Cell Activity in a Mouse Model of Autoimmune Arthritis

(2012) S. Oh et al.   JOURNAL OF IMMUNOLOGY

CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire

(2012) J. Verhagen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoglobulin Analysis Tool: A Novel Tool for the Analysis of Human and Mouse Heavy and Light Chain Transcripts

(2012) Tobias Rogosch et al.   Frontiers in Immunology

Impaired suppression of synovial fluid CD4+CD25− T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells

(2011) Susanne Haufe et al.   ARTHRITIS AND RHEUMATISM

Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope

(2011) Sampath Prahalad et al.   ARTHRITIS AND RHEUMATISM

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

(2011) E. J. Wehrens et al.   BLOOD

T-Cell Compartment in Synovial Fluid of Pediatric Patients with JIA Correlates with Disease Phenotype

(2011) Ninette Amariglio et al.   JOURNAL OF CLINICAL IMMUNOLOGY

TCR Bias of In Vivo Expanded T Cells in Pancreatic Islets and Spleen at the Onset in Human Type 1 Diabetes

(2011) E. Codina-Busqueta et al.   JOURNAL OF IMMUNOLOGY

Juvenile idiopathic arthritis

(2011) Berent Prakken et al.   LANCET

Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis

(2010) Nicolino Ruperto et al.   ARTHRITIS AND RHEUMATISM

Juvenile idiopathic arthritis and HLA Class I and Class II interactions and age-at-onset effects

(2010) Jill A. Hollenbach et al.   ARTHRITIS AND RHEUMATISM

Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function

(2010) S. Tanaka et al.   JOURNAL OF IMMUNOLOGY

High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets

(2010) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

(2009) A. Le Campion et al.   BLOOD

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Oligoarticular and polyarticular JIA: epidemiology and pathogenesis

(2009) Claudia Macaubas et al.   Nature Reviews Rheumatology

Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells

(2009) C. Ferreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

(2008) Kiran Nistala et al.   ARTHRITIS AND RHEUMATISM