Characteristics of an ideal nebulized antibiotic for the treatment of pneumonia in the intubated patient

Clinical applications of pulmonary delivery of antibiotics

(2015) Patrick A. Flume et al.   ADVANCED DRUG DELIVERY REVIEWS

Novel Approaches Are Needed to Develop Tomorrow’s Antibacterial Therapies

(2015) Brad Spellberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria

(2015) Matteo Bassetti et al.   INTENSIVE CARE MEDICINE

Five-year trends for ventilator-associated pneumonia: Correlation between microbiological findings and antimicrobial drug consumption

(2015) Vincent Fihman et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The effect of pathophysiology on pharmacokinetics in the critically ill patient — Concepts appraised by the example of antimicrobial agents

(2014) Stijn I. Blot et al.   ADVANCED DRUG DELIVERY REVIEWS

Reduction of Bacterial Resistance with Inhaled Antibiotics in the Intensive Care Unit

(2014) Lucy B. Palmer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Potentiation Effects of Amikacin and Fosfomycin against Selected Amikacin-Nonsusceptible Gram-Negative Respiratory Tract Pathogens

(2014) A. Bruce Montgomery et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Phase 3 Randomized Double-Blind Comparison of Ceftobiprole Medocaril Versus Ceftazidime Plus Linezolid for the Treatment of Hospital-Acquired Pneumonia

(2014) S. S. Awad et al.   CLINICAL INFECTIOUS DISEASES

A Randomized Double-Blind Placebo-Controlled Dose-Escalation Phase 1 Study of Aerosolized Amikacin and Fosfomycin Delivered via the PARI Investigational eFlow® Inline Nebulizer System in Mechanically Ventilated Patients

(2014) A. Bruce Montgomery et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Aerosolized antibiotics

(2013) Marin H. Kollef et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Aerosol therapy during mechanical ventilation: an international survey

(2013) Stephan Ehrmann et al.   INTENSIVE CARE MEDICINE

Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies

(2013) Wilhelmina G Melsen et al.   LANCET INFECTIOUS DISEASES

Aerosolized Antibiotics for Ventilator-associated Pneumonia

(2012) Jean-Jacques Rouby et al.   ANESTHESIOLOGY

Efficacy of High-dose Nebulized Colistin in Ventilator-associated Pneumonia Caused by Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii

(2012) Qin Lu et al.   ANESTHESIOLOGY

Introduction to Drug Pharmacokinetics in the Critically III Patient

(2012) Brian S. Smith et al.   CHEST

Humidification During Invasive and Noninvasive Mechanical Ventilation: 2012

(2012) R. D. Restrepo et al.   Respiratory Care

Inhaled antibiotic therapy for ventilator-associated tracheobronchitis and ventilator-associated pneumonia: an Update

(2011) Tareq Abu-Salah et al.   ADVANCES IN THERAPY

Nebulized Ceftazidime and Amikacin in Ventilator-associated Pneumonia Caused byPseudomonas aeruginosa

(2011) Qin Lu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Aerosolized Antibiotics in the Intensive Care Unit

(2011) Lucy B. Palmer   CLINICS IN CHEST MEDICINE

What the pulmonary specialist should know about the new inhalation therapies

(2011) B. L. Laube et al.   EUROPEAN RESPIRATORY JOURNAL

Aerosolized antibiotics for treating hospital-acquired and ventilator-associated pneumonia

(2011) G Christopher Wood   Expert Review of Anti-Infective Therapy

BAY41-6551 achieves bactericidal tracheal aspirate amikacin concentrations in mechanically ventilated patients with Gram-negative pneumonia

(2011) Michael S. Niederman et al.   INTENSIVE CARE MEDICINE

Current use of aminoglycosides: indications, pharmacokinetics and monitoring for toxicity

(2011) M. L. Avent et al.   INTERNAL MEDICINE JOURNAL

Steady-State Pharmacokinetics and BAL Concentration of Colistin in Critically Ill Patients After IV Colistin Methanesulfonate Administration

(2010) Roberto Imberti et al.   CHEST

Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa

(2010) Qin Lu et al.   INTENSIVE CARE MEDICINE

Consensus Summary of Aerosolized Antimicrobial Agents: Application of Guideline Criteria

(2010) Jennifer Le et al.   PHARMACOTHERAPY

Empiric Therapy for Gram-Negative Pathogens in Nosocomial and Health Care-Associated Pneumonia: Starting With the End in Mind

(2010) Amy Arnold et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study*

(2009) Jean Chastre et al.   CRITICAL CARE MEDICINE

Meta-analysis of doripenem vs comparators in patients withpseudomonasinfections enrolled in four phase III efficacy and safety clinical trials

(2009) Stephen G. Jenkins et al.   CURRENT MEDICAL RESEARCH AND OPINION

Aerosolized antibiotics to treat ventilator-associated pneumonia

(2009) Charles-Edouard Luyt et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Aerosol Antibiotics in Cystic Fibrosis

(2009) David E Geller   Respiratory Care

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Aerosol Delivery During Mechanical Ventilation: From Basic Techniques to New Devices

(2008) Rajiv Dhand   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy

(2008) R. G. Masterton et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY