TLR4 signaling in VTA dopaminergic neurons regulates impulsivity through tyrosine hydroxylase modulation

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Peripheral HMGB1-induced hyperalgesia in mice: Redox state-dependent distinct roles of RAGE and TLR4

(2016) Daichi Yamasoba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

(2016) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impulsivity as a Multifaceted Construct Related to Excessive Drinking Among UK Students

(2015) A.J. Caswell et al.   ALCOHOL AND ALCOHOLISM

Delay discounting, self-control, and substance use among adult drug court participants

(2015) Craig G.A. Jones et al.   BEHAVIOURAL PHARMACOLOGY

Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles

(2015) Valentina Calabrese et al.   MOLECULAR IMMUNOLOGY

The dopamine theory of addiction: 40 years of highs and lows

(2015) David J. Nutt et al.   NATURE REVIEWS NEUROSCIENCE

CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration

(2015) Harry L June et al.   NEUROPSYCHOPHARMACOLOGY

Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive

(2015) Yolanda Peña-Oliver et al.   PLoS One

Impulsivity: Mechanisms, moderators and implications for addictive behaviors

(2014) Matthew J. Gullo et al.   ADDICTIVE BEHAVIORS

Increased Delay Discounting Tracks with a High Ethanol-Seeking Phenotype and Subsequent Ethanol Seeking But Not Consumption

(2014) S. Wesley Beckwith et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

CC-Chemokine Ligand 2 Facilitates Conditioned Place Preference to Methamphetamine Through the Activation of Dopamine Systems

(2014) Naoki Wakida et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats

(2013) William J. McBride et al.   ALCOHOL

Effect of Chronic Delivery of the Toll-like Receptor 4 Antagonist (+)-Naltrexone on Incubation of Heroin Craving

(2013) Florence R. Theberge et al.   BIOLOGICAL PSYCHIATRY

Frontal Lobe γ-Aminobutyric Acid Levels During Adolescence: Associations with Impulsivity and Response Inhibition

(2013) Marisa M. Silveri et al.   BIOLOGICAL PSYCHIATRY

Impulsiveness mediates the association betweenGABRA2SNPs and lifetime alcohol problems

(2013) S. Villafuerte et al.   GENES BRAIN AND BEHAVIOR

Neuron-derived IgG protects dopaminergic neurons from insult by 6-OHDA and activates microglia through the FcγR I and TLR4 pathways

(2013) Jie Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway

(2013) Kurt Lucas et al.   MOLECULAR NEUROBIOLOGY

Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity

(2013) Pierre Trifilieff et al.   NEUROPHARMACOLOGY

Hyperphosphorylation of CREB in human dopaminergic neurons

(2013) Bushra Y. Ahmed et al.   NEUROREPORT

From the ventral to the dorsal striatum: Devolving views of their roles in drug addiction

(2013) Barry J. Everitt et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

How Phenotype and Developmental Stage Affect the Genes We Find: GABRA2 and Impulsivity

(2013) Danielle M. Dick et al.   Twin Research and Human Genetics

Behavioral and Neurotransmitter Specific Roles for the Ventral Tegmental Area in Reinforcer-Seeking and Intake

(2012) Cristine L. Czachowski et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Polymorphism in the Tyrosine Hydroxylase (TH) Gene Is Associated with Activity-Impulsivity in German Shepherd Dogs

(2012) Enikő Kubinyi et al.   PLoS One

Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators

(2012) Suzanne J. Reeves et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

The relationship between impulsivity and craving in alcohol dependent patients

(2012) L. Joos et al.   PSYCHOPHARMACOLOGY

Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies

(2011) Yuri A. Blednov et al.   ADDICTION BIOLOGY

Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage

(2011) María Pascual et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like receptor 4-mediated cAMP production up-regulates B-cell activating factor expression in Raw264.7 macrophages

(2011) Eun-Yi Moon et al.   EXPERIMENTAL CELL RESEARCH

Opiate versus psychostimulant addiction: the differences do matter

(2011) Aldo Badiani et al.   NATURE REVIEWS NEUROSCIENCE

Binge alcohol drinking is associated with GABAA  2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdala

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delayed reward discounting and addictive behavior: a meta-analysis

(2011) James MacKillop et al.   PSYCHOPHARMACOLOGY

Toll-like receptor signaling in neural plasticity and disease

(2011) Eitan Okun et al.   TRENDS IN NEUROSCIENCES

Understanding the construct of impulsivity and its relationship to alcohol use disorders

(2010) Danielle M. Dick et al.   ADDICTION BIOLOGY

High-Alcohol Preferring Mice Are More Impulsive Than Low-Alcohol Preferring Mice as Measured in the Delay Discounting Task

(2009) B. G. Oberlin et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Impulsivity and response inhibition in alcohol dependence and problem gambling

(2009) Andrew J. Lawrence et al.   PSYCHOPHARMACOLOGY

The Role of Behavioral Impulsivity in the Development of Alcohol Dependence: A 4-Year Follow-Up Study

(2008) Gabriel Rubio et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Rats bred for high alcohol drinking are more sensitive to delayed and probabilistic outcomes

(2008) C. J. Wilhelm et al.   GENES BRAIN AND BEHAVIOR

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

(2008) Nora D. Volkow et al.   NEUROIMAGE

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

(2008) R.G. Nair-Roberts et al.   NEUROSCIENCE

Regulating gene transcription in response to cyclic AMP elevation

(2007) William A. Sands et al.   CELLULAR SIGNALLING