MicroRNA-21 activation of Akt via PTEN is involved in the epithelial–mesenchymal transition and malignant transformation of human keratinocytes induced by arsenite
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Title
MicroRNA-21 activation of Akt via PTEN is involved in the epithelial–mesenchymal transition and malignant transformation of human keratinocytes induced by arsenite
Authors
Keywords
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Journal
Toxicology Research
Volume 5, Issue 4, Pages 1140-1147
Publisher
Royal Society of Chemistry (RSC)
Online
2016-05-09
DOI
10.1039/c6tx00041j
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- Arsenic: an ancient toxicant of continuous public health impact, from Iceman Ötzi until now
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- Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN
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- Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition
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- Asymmetric PI(3,4,5)P3 and Akt Signaling Mediates Chemotaxis of Axonal Growth Cones
- (2011) S. J. Henle et al. JOURNAL OF NEUROSCIENCE
- Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells
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- The Repressive Effect of NF-κB on p53 by Mot-2 Is Involved in Human Keratinocyte Transformation Induced by Low Levels of Arsenite
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- Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure
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