MicroRNA-21 activation of Akt via PTEN is involved in the epithelial–mesenchymal transition and malignant transformation of human keratinocytes induced by arsenite

MiR-21: an environmental driver of malignant melanoma?

(2015) Bodo C Melnik   Journal of Translational Medicine

The IL-6/STAT3 pathway via miR-21 is involved in the neoplastic and metastatic properties of arsenite-transformed human keratinocytes

(2015) Xiaolin Lu et al.   TOXICOLOGY LETTERS

Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

(2015) Frederick J. Sheedy   Frontiers in Immunology

The Regulatory Role of MicroRNAs in EMT and Cancer

(2015) Apostolos Zaravinos   Journal of Oncology

PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

(2013) Longlong Bao et al.   CANCER LETTERS

Involvement of HIF-2α-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells

(2013) Yuan Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

EMT and CSC-like properties mediated by the IKKβ/IκBα/RelA signal pathway via the transcriptional regulator, Snail, are involved in the arsenite-induced neoplastic transformation of human keratinocytes

(2012) Rongrong Jiang et al.   ARCHIVES OF TOXICOLOGY

Arsenic: an ancient toxicant of continuous public health impact, from Iceman Ötzi until now

(2012) Hermann M. Bolt   ARCHIVES OF TOXICOLOGY

PTEN and melanomagenesis

(2012) Alejandro Conde-Perez et al.   Future Oncology

Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN

(2012) Mingli Han et al.   PLoS One

Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition

(2011) Chun-Yu Lin et al.   CANCER SCIENCE

Asymmetric PI(3,4,5)P3 and Akt Signaling Mediates Chemotaxis of Axonal Growth Cones

(2011) S. J. Henle et al.   JOURNAL OF NEUROSCIENCE

Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells

(2011) Mingli Han et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Epithelial–mesenchymal transition in the skin

(2010) Motonobu Nakamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The Repressive Effect of NF-κB on p53 by Mot-2 Is Involved in Human Keratinocyte Transformation Induced by Low Levels of Arsenite

(2010) Yuan Li et al.   TOXICOLOGICAL SCIENCES

Arsenite induced poly(ADP-ribosyl)ation of tumor suppressor P53 in human skin keratinocytes as a possible mechanism for carcinogenesis associated with arsenic exposure

(2009) Elena V. Komissarova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY