STX0119 ameliorates arthritis in SKG mice via inhibiting T helper 17

Coenzyme Q10 suppresses Th17 cells and osteoclast differentiation and ameliorates experimental autoimmune arthritis mice

(2015) JooYeon Jhun et al.   IMMUNOLOGY LETTERS

Red Ginseng Extract Ameliorates Autoimmune Arthritis via Regulation of STAT3 Pathway, Th17/Treg Balance, and Osteoclastogenesis in Mice and Human

(2014) JooYeon Jhun et al.   MEDIATORS OF INFLAMMATION

EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control

(2014) Eun-Ji Yang et al.   PLoS One

STA-21, a Promising STAT-3 Inhibitor That Reciprocally Regulates Th17 and Treg Cells, Inhibits Osteoclastogenesis in Mice and Humans and Alleviates Autoimmune Inflammation in an Experimental Model of Rheumatoid Arthritis

(2013) Jin-Sil Park et al.   Arthritis & Rheumatology

IL-6, IL-17 and STAT3: a holy trinity in auto-immunity?

(2012) Annalisa Camporeale   Frontiers in Bioscience-Landmark

Disturbed Th17/Treg balance in patients with rheumatoid arthritis

(2011) Qian Niu et al.   RHEUMATOLOGY INTERNATIONAL

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

Th17 cells can provide B cell help in autoantibody induced arthritis

(2010) Cynthia L. Hickman-Brecks et al.   JOURNAL OF AUTOIMMUNITY

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Identification of a New Series of STAT3 Inhibitors by Virtual Screening

(2010) Kenji Matsuno et al.   ACS Medicinal Chemistry Letters

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

(2009) Lin Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE